Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Kyle L Morris"'
Autor:
Benjamin G Horst, Adam L Yokom, Daniel J Rosenberg, Kyle L Morris, Michal Hammel, James H Hurley, Michael A Marletta
Publikováno v:
eLife, Vol 8 (2019)
Soluble guanylate cyclase (sGC) is the primary receptor for nitric oxide (NO) in mammalian nitric oxide signaling. We determined structures of full-length Manduca sexta sGC in both inactive and active states using cryo-electron microscopy. NO and the
Externí odkaz:
https://doaj.org/article/182c15c0deb94199bbde24ac6600a2c3
Autor:
Robert E. Turnbull, Louise Fairall, Almutasem Saleh, Emma Kelsall, Kyle L. Morris, T. J. Ragan, Christos G. Savva, Aditya Chandru, Christopher J. Millard, Olga V. Makarova, Corinne J. Smith, Alan M. Roseman, Andrew M. Fry, Shaun M. Cowley, John W. R. Schwabe
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The MiDAC complex recruits class I histone deacetylases to chromatin but little is known about its precise structure and function. Here, the authors explore the role of MiDAC in the cell cycle and during mouse embryogenesis, and present cryoEM struct
Externí odkaz:
https://doaj.org/article/6a71d260306a424c936ce21edc133482
Autor:
Sarah M. Smith, Gabrielle Laroque, Katherine M. Wood, Kyle L. Morris, Alan M. Roseman, Richard B. Sessions, Stephen J. Royle, Corinne J. Smith, Frances M. Brodsky
Publikováno v:
Biophysical Journal. 122:514a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::422aa4a849de3499244d3daea522d7ac
https://doi.org/10.1016/j.bpj.2022.11.2736
https://doi.org/10.1016/j.bpj.2022.11.2736
Autor:
Katherine M. Wood, Alan M. Roseman, Richard B. Sessions, Gabrielle Larocque, Kyle L. Morris, Sarah Marie Smith, Stephen J. Royle, Corinne J. Smith
Publikováno v:
Sarah, S, Roseman, A & Smith, C J 2021, ' Multi-modal adaptor-clathrin contacts drive coated vesicle assembly ', EMBO Journal, vol. 40, no. 19, e108795 . https://doi.org/10.15252/embj.2021108795
The EMBO Journal
Smith, S M, Larocque, G, Wood, K M, Morris, K L, Roseman, A M, Sessions, R B, Royle, S J & Smith, C J 2021, ' Multi-modal adaptor-clathrin contacts drive coated vesicle assembly ', EMBO Journal, vol. 40, no. 19, e108795, pp. 1-16 . https://doi.org/10.15252/embj.2021108795
The EMBO Journal
Smith, S M, Larocque, G, Wood, K M, Morris, K L, Roseman, A M, Sessions, R B, Royle, S J & Smith, C J 2021, ' Multi-modal adaptor-clathrin contacts drive coated vesicle assembly ', EMBO Journal, vol. 40, no. 19, e108795, pp. 1-16 . https://doi.org/10.15252/embj.2021108795
Clathrin‐coated pits are formed by the recognition of membrane and cargo by the AP2 complex and the subsequent recruitment of clathrin triskelia. A role for AP2 in coated‐pit assembly beyond initial clathrin recruitment has not been explored. Cla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e102381816f54d797395af92e6a07d
https://www.research.manchester.ac.uk/portal/en/publications/multimodal-adaptorclathrin-contacts-drive-coated-vesicle-assembly(adc49815-2b9c-4ca1-8234-d3f692865210).html
https://www.research.manchester.ac.uk/portal/en/publications/multimodal-adaptorclathrin-contacts-drive-coated-vesicle-assembly(adc49815-2b9c-4ca1-8234-d3f692865210).html
Autor:
Almutasem Saleh, Christos G. Savva, Christopher J. Millard, Olga V. Makarova, Louise Fairall, John W.R. Schwabe, Emma J. Kelsall, Robert E. Turnbull, Alan M. Roseman, Aditya Chandru, Corinne J. Smith, Kyle L. Morris, Andrew M. Fry, Timothy J. Ragan, Shaun M. Cowley
Publikováno v:
Turnbull, R, Smith, C J, Roseman, A & Schwabe, J W R 2020, ' The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure ', Nature Communications, vol. 11, no. 3252, 3252, pp. 1-15 . https://doi.org/10.1038/s41467-020-17078-8
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
MiDAC is one of seven distinct, large multi-protein complexes that recruit class I histone deacetylases to the genome to regulate gene expression. Despite implications of involvement in cell cycle regulation and in several cancers, surprisingly littl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fafeeb774ac3fd44e47ba717247f4ac
https://doi.org/10.1038/s41467-020-17078-8
https://doi.org/10.1038/s41467-020-17078-8
Autor:
Corinne J. Smith, Mary Halebian, Joseph R. Jones, Yifan Cheng, Alexander D. Cameron, Michael Baker, Jean Paul Armache, Richard B. Sessions, Shenping Wu, Amaurys Avila Ibarra, Kyle L. Morris
Publikováno v:
Morris, K L, Jones, J R, Halebian, M, Wu, S, Baker, M, Armache, J-P, Avila Ibarra, A, Sessions, R B, Cameron, A D, Cheng, Y & Smith, C J I 2019, ' Cryo-EM of multiple cage architectures reveals a universal mode of clathrin self-assembly ', Nature Structural and Molecular Biology, vol. 26, pp. 890-898 . https://doi.org/10.1038/s41594-019-0292-0
Nature structural & molecular biology
Nature structural & molecular biology, vol 26, iss 10
Nature structural & molecular biology
Nature structural & molecular biology, vol 26, iss 10
Clathrin forms diverse lattice and cage structures that change size and shape rapidly in response to the needs of eukaryotic cells during clathrin-mediated endocytosis and intracellular trafficking. We present the cryo-EM structure and molecular mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5bb9204f57772f468072b10f3312c8
http://wrap.warwick.ac.uk/126169/1/WRAP-Cryo-EM-multiple-cage-architectures-universal-clathrin-Morris-2019.pdf
http://wrap.warwick.ac.uk/126169/1/WRAP-Cryo-EM-multiple-cage-architectures-universal-clathrin-Morris-2019.pdf
Autor:
Adam L. Yokom, Daniel J. Rosenberg, Michael A. Marletta, Michal Hammel, Benjamin G. Horst, Kyle L. Morris, James H. Hurley
Publikováno v:
eLife, Vol 8 (2019)
Soluble guanylate cyclase (sGC) is the primary receptor for nitric oxide (NO) in mammalian nitric oxide signaling. We determined structures of full-lengthManduca sextasGC in both inactive and active states using cryo-electron microscopy. NO and the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2858596225776650e0f66b115e1f3adc
https://doi.org/10.1101/729418
https://doi.org/10.1101/729418
Autor:
Clara Aicart-Ramos, Fernando Moreno-Herrero, Pilar Gutiérrez-Escribano, Holger B. Kramer, Juri Rappsilber, Alex Montoya, Roger Solé-Soler, Kyle L. Morris, Silvia Hormeño, Jordi Torres-Rosell, Francis J. O’Reilly, Luis Aragón, Julene Madariaga-Marcos, Ricardo Aramayo
Publikováno v:
Molecular Cell
Recercat. Dipósit de la Recerca de Catalunya
instname
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Gutierrez-Escribano, P, Hormeño, S, Madariaga-Marcos, J, Solé-Soler, R, O’Reilly, F J, Morris, K, Aicart-Ramos, C, Aramayo, R, Montoya, A, Kramer, H, Rappsilber, J, Torres-Rosell, J, Moreno-Herrero, F & Aragon, L 2020, ' Purified Smc5/6 complex exhibits DNA substrate recognition and compaction ', Molecular Cell, vol. 80, no. 6, pp. 1039-1054.e6 . https://doi.org/10.1016/j.molcel.2020.11.012
Digital.CSIC. Repositorio Institucional del CSIC
Repositorio Abierto de la UdL
Universitad de Lleida
Recercat. Dipósit de la Recerca de Catalunya
instname
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Gutierrez-Escribano, P, Hormeño, S, Madariaga-Marcos, J, Solé-Soler, R, O’Reilly, F J, Morris, K, Aicart-Ramos, C, Aramayo, R, Montoya, A, Kramer, H, Rappsilber, J, Torres-Rosell, J, Moreno-Herrero, F & Aragon, L 2020, ' Purified Smc5/6 complex exhibits DNA substrate recognition and compaction ', Molecular Cell, vol. 80, no. 6, pp. 1039-1054.e6 . https://doi.org/10.1016/j.molcel.2020.11.012
Digital.CSIC. Repositorio Institucional del CSIC
Repositorio Abierto de la UdL
Universitad de Lleida
Summary Eukaryotic SMC complexes, cohesin, condensin, and Smc5/6, use ATP hydrolysis to power a plethora of functions requiring organization and restructuring of eukaryotic chromosomes in interphase and during mitosis. The Smc5/6 mechanism of action
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a646f4a6f60fc03ec5e179a128ebfc9
https://doi.org/10.1016/j.molcel.2020.11.012
https://doi.org/10.1016/j.molcel.2020.11.012
Autor:
Kyle L. Morris, Christina M. Stürzel, Xuefeng Ren, Frank Kirchhoff, James H. Hurley, Cosmo Z. Buffalo, Elena Heusinger
SummaryThe HIV accessory protein Nef counteracts immune defenses by subverting coated vesicle pathways. The 3.7 Å cryo-EM structure of a closed trimer of the clathrin adaptor AP-1, the small GTPase Arf1, HIV-1 Nef, and the cytosolic tail of the rest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0ffe06add2ddba852312cc98ef455f