Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kyle J. Sommers"'
Autor:
Kyle J. Sommers, Marina E. Michaud, Cody E. Hogue, Amber M. Scharnow, Lauren E. Amoo, Ashley A. Petersen, Robert G. Carden, Kevin P. C. Minbiole, William M. Wuest
Publikováno v:
ACS Infect Dis
Quaternary ammonium compounds (QACs) serve as mainstays in the formulation of disinfectants and antiseptics. However, an over-reliance and misuse of our limited QAC arsenal has driven the development and spread of resistance to these compounds, as we
Autor:
Kyle J. Sommers, William M. Wuest, Ryan A. Allen, Robert G. Carden, Jacob W. Black, Renee C Kontos, Kevin P. C. Minbiole, Brian S. Bentley, Savannah J Post
Publikováno v:
ChemMedChem
Inspired by the incorporation of metallocene functionalities into a variety of bioactive structures, particularly antimicrobial peptides, we endeavored to broaden the structural variety of quaternary ammonium compounds (QACs) by the incorporation of
Autor:
Javier A. Feliciano, Austin J. Leitgeb, Cassandra L. Schrank, Kyle J. Sommers, William M. Wuest, Kevin P. C. Minbiole, Robert G. Carden
Publikováno v:
ChemMedChem
The prevalence of quaternary ammonium compounds (QACs) as common disinfecting agents for the past century has led bacteria to develop resistance to such compounds. Given the alarming increase in resistant strains, new strategies are required to comba
Autor:
Austin J. Leitgeb, Javier A. Feliciano, Hugo A. Sanchez, Ryan A. Allen, Kelly R. Morrison, Kyle J. Sommers, Robert G. Carden, William M. Wuest, Kevin P. C. Minbiole
Publikováno v:
ChemMedChem
Thirty-six biscationic quaternary ammonium compounds were efficiently synthesized in one step to examine the effect of molecular geometry of two-carbon linkers on antimicrobial activity. The synthesized compounds showed strong antimicrobial activity
Autor:
Javier A. Feliciano, Kelly R. Morrison, Austin J. Leitgeb, William M. Wuest, Kevin P. C. Minbiole, Robert G. Carden, Ryan A. Allen, Kyle J. Sommers, Hugo A. Sanchez
Publikováno v:
ChemMedChem. 15:660-660