Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Kyle J Gerber"'
Regulation of actions and habits by ventral hippocampal trkB and adolescent corticosteroid exposure.
Autor:
Elizabeth T Barfield, Kyle J Gerber, Kelsey S Zimmermann, Kerry J Ressler, Ryan G Parsons, Shannon L Gourley
Publikováno v:
PLoS Biology, Vol 15, Iss 11, p e2003000 (2017)
In humans and rodents, stress promotes habit-based behaviors that can interfere with action-outcome decision-making. Further, developmental stressor exposure confers long-term habit biases across rodent-primate species. Despite these homologies, mech
Externí odkaz:
https://doaj.org/article/6bc5262554c4421ea0560af14880d045
Autor:
Elena Faccenda, Adam J Pawson, Kirk M. Druey, David L. Roman, Mackenzie M. Spicer, Michael Spedding, Rory A. Fisher, Mohammed Alqinyah, Hoa Phan, Benita Sjögren, Christopher G. Sobey, Yalda Zolghadri, Arthur Christopoulos, Shelley B. Hooks, Simon D. Harding, Thiruma V. Arumugam, Laurie P. Sutton, Behirda Karaj, Stephen P.H. Alexander, Jae-Kyung Lee, Christopher R. Bodle, Peter Buneman, Eamonn Kelly, Zili Luo, Jörg Striessnig, Jane F. Armstrong, Jamie A. Davies, Vincent Shaw, Keqiang Xie, Shreoshi Pal Choudhuri, Katherine E. Squires, Luke D. Mascarenhas, Katelin E. Ahlers-Dannen, Harrison J. McNabb, Kyle J. Gerber, Menbere Wendimu, John A. Peters, Anthony P. Davenport, Doriano Fabbro, Somayeh Layeghi-Ghalehsoukhteh, Havish S. Kantheti, Emma L. Veale, Bandana Chakravarti, Thomas M. Wilkie, Carolina Montañez-Miranda, John R. Hepler, Kirill A. Martemyanov, Christopher Southan, John A. Cidlowski, Qian Zhang, Alistair Mathie, Josephine Buo Dagner, Osita W. Ogujiofor
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d71b6cad2f29e8755e256dd641b2af
Autor:
Serena M. Dudek, Duc M. Duong, John R. Hepler, Nicholas T. Seyfried, Eric B. Dammer, Qiudong Deng, Kyle J. Gerber
Publikováno v:
J Proteome Res
The hippocampus is well established as an essential brain center for learning and memory. Within the hippocampus, recent studies show that area CA2 is important for social memory, and is an anomaly compared to its better understood neighboring region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e280087d2a24c0e6cce4e02ec13c23fe
https://doi.org/10.1021/acs.jproteome.9b00103
https://doi.org/10.1021/acs.jproteome.9b00103
Autor:
Carolina Montañez-Miranda, Mohammed Alqinyah, Thomas M. Wilkie, Benita Sjögren, David L. Roman, Somayeh Layeghi-Ghalehsoukhteh, Yalda Zolghadri, Osita W. Ogujiofor, John R. Hepler, Behirda Karaj, Shelley B. Hooks, Havish S. Kantheti, Menbere Wendimu, Rory A. Fisher, Jae-Kyung Lee, Katherine E. Squires, Qian Zhang, Bandana Chakravarti, Katelin E. Ahlers-Dannen, Keqiang Xie, Josephine Bou Dagher, Vincent Shaw, Christopher Bodle, Shreoshi Pal Choudhuri, Harrison J. McNabb, Kyle J. Gerber, Kirill A. Martemyanov, Mackenzie M. Spicer, Kirk M. Druey, Luke D. Mascarenhas, Hoa Phan Thi Nhu, Zili Luo, Laurie P. Sutton
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2021
Regulator of G protein Signaling, or RGS, proteins serve an important regulatory role in signaling mediated by G protein-coupled receptors (GPCRs). They all share a common RGS domain that directly interacts with active, GTP-bound Gα subunits of hete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc303e614e9a87223ee5a4f03a6459ea
https://doi.org/10.2218/gtopdb/f891/2021.2
https://doi.org/10.2218/gtopdb/f891/2021.2
Autor:
Carolina Montañez-Miranda, Kirill A. Martemyanov, John R. Hepler, Yalda Zolghadri, Katelin E. Ahlers-Dannen, Luke D. Mascarenhas, Rory A. Fisher, Kirk M. Druey, Josephine Bou Dagher, Thomas M. Wilkie, Zili Luo, Behirda Karaj, Havish S. Kantheti, David L. Roman, Christopher Bodle, Shreoshi Pal Choudhuri, Kyle J. Gerber, Hoa Phan Thi Nhu, Jae-Kyung Lee, Menbere Wendimu, Katherine E. Squires, Laurie P. Sutton, Bandana Chakravarti, Shelley B. Hooks, Vincent Shaw, Mohammed Alqinyah, Keqiang Xie, Benita Sjögren, Mackenzie M. Spicer
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2020
Regulator of G protein Signaling, or RGS, proteins serve an important regulatory role in signaling mediated by G protein-coupled receptors (GPCRs). They all share a common RGS domain that directly interacts with active, GTP-bound Gα subunits of hete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35af8687b1e5ef6090b9ef70c0979d44
https://doi.org/10.2218/gtopdb/f891/2020.5
https://doi.org/10.2218/gtopdb/f891/2020.5
Autor:
David Weinshenker, Suneela Ramineni, Feng-jue Shu, Christopher D. Scharer, Matthew C. Tillman, John R. Hepler, Jason P. Schroeder, Kyle J. Gerber, Katherine E. Squires, Meilan Zhao, Ramendra N. Saha, Eric A. Ortlund, Serena M. Dudek, Carolina Montañez-Miranda, Daniel Lustberg
Publikováno v:
The Journal of Biological Chemistry
The human genome contains vast genetic diversity as naturally occurring coding variants, yet the impact of these variants on protein function and physiology is poorly understood. RGS14 is a multifunctional signaling protein that suppresses synaptic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba6b9a078a564b3d20bb998c3c1d322
https://escholarship.org/uc/item/7xb4h01s
https://escholarship.org/uc/item/7xb4h01s
Autor:
Havish S. Kantheti, Christopher R. Bodle, Zili Luo, Vincent Shaw, Laurie P. Sutton, John R. Hepler, Mohammed Alqinyah, Shreoshi Pal Choudhuri, Katelin E. Ahlers-Dannen, Kyle J. Gerber, Hoa Phan Thi Nhu, Thomas M. Wilkie, Yalda Zolghadri, Keqiang Xie, Benita Sjögren, Kirill A. Martemyanov, Katherine E. Squires, Mackenzie M. Spicer, Rory A. Fisher, Behirda Karaj, Luke D. Mascarenhas, Bandana Chakravarti, Shelley B. Hooks, Josephine Bou Dagher, Kirk M. Druey, David L. Roman, Jae-Kyung Lee
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2020
Regulator of G protein Signaling, or RGS, proteins serve an important regulatory role in signaling mediated by G protein-coupled receptors (GPCRs). They all share a common RGS domain that directly interacts with active, GTP-bound Gα subunits of hete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::830713a3002304dd319054015f19d814
https://doi.org/10.2218/gtopdb/f891/2020.4
https://doi.org/10.2218/gtopdb/f891/2020.4
Publikováno v:
Oncoimmunology
article-version (VoR) Version of Record
OncoImmunology, Vol 9, Iss 1 (2020)
article-version (VoR) Version of Record
OncoImmunology, Vol 9, Iss 1 (2020)
The cyclin-dependent kinase inhibitor p27Kip1 is a tumor suppressor whose intrinsic activity in cancer cells correlates with tumor aggressiveness, invasiveness, and impaired tumor cell differentiation. Here we explore whether p27Kip1 indirectly influ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fefec024ff9d379512785dae8eb83dd2
https://doi.org/10.1080/2162402x.2020.1847832
https://doi.org/10.1080/2162402x.2020.1847832
Publikováno v:
Journal of Biological Chemistry. 293:14616-14631
Regulator of G protein signaling 14 (RGS14) is a multifunctional brain scaffolding protein that integrates G protein and Ras/ERK signaling pathways. It is also a nucleocytoplasmic shuttling protein. RGS14 binds active Gαi/o via its RGS domain, Raf a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69271c260e2df82a0859af4b062a4ccd
https://doi.org/10.1074/jbc.ra118.002816
https://doi.org/10.1074/jbc.ra118.002816
Autor:
Nicholas T. Seyfried, Serena M. Dudek, John R. Hepler, Eric B. Dammer, Devrishi Goswami, Duc M. Duong, Jenny J. Yang, Kyle J. Gerber, Paul R. Evans, Daniel Lustberg, Juan Zou, Patrick R. Griffin
Publikováno v:
Journal of Proteome Research. 17:1700-1711
Regulator of G Protein Signaling 14 (RGS14) is a complex scaffolding protein that integrates G protein and MAPK signaling pathways. In the adult mouse brain, RGS14 is predominantly expressed in hippocampal CA2 neurons where it naturally inhibits syna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::461c694334f519624abf1c2c3bd7c56f
https://doi.org/10.1021/acs.jproteome.8b00027
https://doi.org/10.1021/acs.jproteome.8b00027