Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kyle Howerton"'
Autor:
Francisco J. Silva, Thomas Ramos, Rafael Gonzalez, Tracy Wang, Kyle Howerton, Chauncey B. Sayre, Francis Pau, Natalia Slepko, Joel Marh, Fariborz Izadyar
Publikováno v:
REPRODUCTION. 135:771-784
Spermatogonial stem cells (SSCs) maintain spermatogenesis by self-renewal and generation of spermatogonia committed to differentiation. Under certainin vitroconditions, SSCs from both neonatal and adult mouse testis can reportedly generate multipoten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e663f0c2262003b67788a27d60bcd1
https://doi.org/10.1530/rep-07-0479
https://doi.org/10.1530/rep-07-0479
Autor:
Kyle Howerton, Ssang-Taek Lim, Dan A. Hanson, Yangmi Lim, Susan J. Fisher, Nicholas Larocque, Xiao Lei Chen, David D. Schlaepfer, Dusko Ilic, Thanh-Trang Vo
Publikováno v:
Molecular Cell. 29:9-22
Summary FAK is known as an integrin- and growth factor-associated tyrosine kinase promoting cell motility. Here we show that, during mouse development, FAK inactivation results in p53- and p21-dependent mesodermal cell growth arrest. Reconstitution o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b899b2c5cb797248b25e3cd599eeb9c
https://doi.org/10.1016/j.molcel.2007.11.031
https://doi.org/10.1016/j.molcel.2007.11.031
Publikováno v:
Cell Communication & Adhesion. 15:379-383
It is often difficult to determine molecular mechanisms leading to early embryonic lethality of genetically modified mice due to lack of cells for further analyses. The authors describe here establishment of mouse embryonic fibroblast (MEF) cell line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e376d6cb5b261211d549557ba9aa02d
https://doi.org/10.1080/15419060802440054
https://doi.org/10.1080/15419060802440054
Autor:
José L. Jorcano, Susan J. Fisher, S Essayem, Gregory Dolganov, Nicholas Larocque, Susan McDonagh, Angel Ramirez, Daniel M. Ramos, Dusko Ilic, Kyle Howerton, Theodora M. Mauro, Louis F. Reichardt, Hilary E. Beggs, Branka Kovacic-Milivojevic, Clark Baumbusch
Publikováno v:
Oncogene. 25:1081-1089
Focal adhesion kinase (FAK) is a critical component in transducing signals downstream of both integrins and growth factor receptors. To determine how the loss of FAK affects the epidermis in vivo, we have generated a mouse model with a keratinocyte-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593d688d592d14084c1ed310dafd9e30
https://doi.org/10.1038/sj.onc.1209130
https://doi.org/10.1038/sj.onc.1209130
Autor:
Jianyu Rao, Kyle Howerton, Alan B. Copperman, Chad Maki, Natan Bar-Chama, Scott Greilach, Jason Barritt, Yung-Chiong Chow, Hongyu H. Zhao, Fariborz Izadyar, Jason Pacchiarotti, Michelle Chow, Constance Yuen, Jadelind Wong, Thomas Ramos
Publikováno v:
Human reproduction (Oxford, England). 26(6)
BACKGROUND: This study was conducted to identify and characterize repopulating spermatogonial stem cells (SSCs) in the adult human testes. METHODS: Testes biopsies from obstructive azoospermic patients and normal segments of human testicular tissue w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad33bb021267e5ea9b99527caddf794
https://pubmed.ncbi.nlm.nih.gov/21349855
https://pubmed.ncbi.nlm.nih.gov/21349855
Autor:
Fariborz Izadyar, Jane Pham, Chad Maki, Joel Marh, Jadelind Wong, Thomas Ramos, Jason Pacchiarotti, Kyle Howerton, Yung-Chiong Chow, Sandra Anorve
Publikováno v:
Differentiation; research in biological diversity. 79(3)
General belief in reproductive biology is that in most mammals female germ line stem cells are differentiated to primary oocytes during fetal development and oogenesis starts from a pool of primordial follicles after birth. This idea has been challen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5120c554d094bbf1c148d2d91ed7306
https://pubmed.ncbi.nlm.nih.gov/20138422
https://pubmed.ncbi.nlm.nih.gov/20138422
Autor:
Clark Baumbusch, Yuji Shino, Dusko Ilic, Branka Kovačič, Daniel N. Streblow, Qin Han, Kyle Howerton, Katsunori Sasaki, Naoko Ogiwara, Nenad Tomašević, Jae Beom Kim, Paul Dazin, Jay A. Nelson, David D. Schlaepfer, Caroline H. Damsky, Kohei Johkura
Publikováno v:
Journal of cell science. 117(Pt 2)
Targeted disruption of the focal adhesion kinase (FAK) gene in mice is lethal at embryonic day 8.5 (E8.5). Vascular defects in FAK-/- mice result from the inability of FAK-deficient endothelial cells to organize themselves into vascular network. We f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf9cf64fa6d50d4d154dcca0e4bcf57
https://pubmed.ncbi.nlm.nih.gov/14657279
https://pubmed.ncbi.nlm.nih.gov/14657279