Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kyle Hernandez"'
Autor:
Amanda M. Saravia-Butler, Jonathan C. Schisler, Deanne Taylor, Afshin Beheshti, Dan Butler, Cem Meydan, Jonathon Foox, Kyle Hernandez, Chris Mozsary, Christopher E. Mason, Robert Meller
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105310- (2022)
Summary: We analyzed RNA sequencing data from nasal swabs used for SARS-CoV-2 testing. 13% of 317 PCR-negative samples contained over 100 reads aligned to multiple regions of the SARS-CoV-2 genome. Differential gene expression analysis compares the h
Externí odkaz:
https://doaj.org/article/45fb75cf3bd54701930dd145e147532a
Autor:
Zhenyu Zhang, Kyle Hernandez, Jeremiah Savage, Shenglai Li, Dan Miller, Stuti Agrawal, Francisco Ortuno, Louis M. Staudt, Allison Heath, Robert L. Grossman
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The Genomic Data Commons repository contains genomic, epigenomic, proteomic and clinical data from the TCGA and TARGET datasets. Here, the authors describe the analysis methods for how these divergent datasets were integrated together.
Externí odkaz:
https://doaj.org/article/6b96ad04560f436984a85fdec0836132
Autor:
Ami V Desai, Stefani Spranger, Thomas F Gajewski, Yuanyuan Zha, Jason J Luke, Peter Pytel, Kyle Hernandez, Samuel L Volchenboum, Susan L Cohn
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Background Tumor-infiltrating CD8+ T cells and neoantigens are predictors of a favorable prognosis and response to immunotherapy with checkpoint inhibitors in many types of adult cancer, but little is known about their role in pediatric malignancies.
Externí odkaz:
https://doaj.org/article/b260b4d6e43c4d658b87dc58bb5c263c
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Pandemic COVID-19 by severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2) infection is facilitated by the ACE2 receptor and protease TMPRSS2. Modestly sized case series have described clinical factors associated with COVID-1
Externí odkaz:
https://doaj.org/article/9836b604345f42ce993febf9233e2ba4
Autor:
Riyue Bao, Kyle Hernandez, Lei Huang, Wenjun Kang, Elizabeth Bartom, Kenan Onel, Samuel Volchenboum, Jorge Andrade
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135800 (2015)
Whole exome sequencing has facilitated the discovery of causal genetic variants associated with human diseases at deep coverage and low cost. In particular, the detection of somatic mutations from tumor/normal pairs has provided insights into the can
Externí odkaz:
https://doaj.org/article/d7f0061cf18f44488b65f03386c5bf23
Autor:
Mark A. Aplebaum, Aashish R. Jha, Alexandre Chlenski, Kyle Hernandez, Christopher J. Mariani, Barbara E. Stranger, Susan L. Cohn
Publikováno v:
Cancer Research. 75:B1-15
Background: In cancer, hypoxia leads to a clinically aggressive phenotype by inducing angiogenesis, altering metabolism, and promoting cell infiltration, invasion and metastasis. Hypoxia also results in specific adaptive genetic changes in Drosophila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ce35159289a09e97c51ec99395d6661
https://doi.org/10.1158/1538-7445.compsysbio-b1-15
https://doi.org/10.1158/1538-7445.compsysbio-b1-15
Autor:
Yuankun Zhu, Miguel Brown, Batsal Devkota, Bailey Farrow, Bogdan Gavrilovic, Allison Heath, Kyle Hernandez, Avi Kelman, Parimala Killada, Meen Chul Kim, Daniel Kolbman, Mateusz Koptyra, Milan Kovacevic, Maarten Leerkes, Alex Lubneuski, Michele Mattioni, Pichai Raman, Adam Resnick, Nikola Skundric, Deanne Taylor, Junjun Zhang, Bo Zhang, Phillip B. Storm
Publikováno v:
Cancer Research. 79:2465-2465
Gabriella Miller Kids First Pediatric Research Program (GMKF) is a nation-wide, multi-year initiative focused on the integration of large-scale clinically annotated genomic data for childhood cancers and structural birth defects supported by the NIH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a48edbf28494578bee9ba732a39d7040
https://doi.org/10.1158/1538-7445.am2019-2465
https://doi.org/10.1158/1538-7445.am2019-2465
Autor:
Puneet, Singh, Clifton O, Brock, Paul A, Volden, Kyle, Hernandez, Maxwell, Skor, Masha, Kocherginsky, Julie E, Park, Matthew J, Brady, Suzanne D, Conzen
Publikováno v:
Obesity (Silver Spring, Md.). 23(11)
To identify glucocorticoid receptor (GR)-associated chromatin sequences and target genes in primary human abdominal subcutaneous fat.GR chromatin immunoprecipitation (ChIP)-sequencing (seq) methodology in subcutaneous human adipocytes treated ex vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0546a450c3480fd176f716881f6c863d
https://pubmed.ncbi.nlm.nih.gov/26408078
https://pubmed.ncbi.nlm.nih.gov/26408078