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Autor:
Adam Yasgar, Ganesha Rai, Daniel Korn, Joshua Hochuli, Anton Simeonov, Rodolpho C. Braga, Alexander Tropsha, Alexey V. Zakharov, Stephen J. Capuzzi, Eugene N. Muratov, Vinicius M. Alves, Kyle H. Bowler
Publikováno v:
Journal of chemical information and modeling. 60(8)
Small, colloidally aggregating molecules (SCAMs) are the most common source of false positives in high-throughput screening (HTS) campaigns. Although SCAMs can be experimentally detected and suppressed by the addition of detergent in the assay buffer