Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kyle G. Kroeck"'
Autor:
Eric M. Lewandowski, Kyle G. Kroeck, Lian M.C. Jacobs, Tyler G. Fenske, Robin N. Witt, Alyssa M. Hintz, Elizabeth R. Ramsden, Xiujun Zhang, Francis Peterson, Brian F. Volkman, Christopher T. Veldkamp, Yu Chen
Publikováno v:
Biochemistry
The human chemokines CCL19 and CCL21 bind to the G-protein coupled receptor (GPCR) CCR7 and play an important role in the trafficking of immune cells, as well as cancer metastasis. Conserved binding sites for sulfotyrosine residues on the receptor co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f708794d43a7b1b708cbed603e4d6421
https://europepmc.org/articles/PMC9254573/
https://europepmc.org/articles/PMC9254573/
Autor:
Afroza Akhtar, Xueji Zhang, Sacco, Sophie E. Darch, Yu Chen, Kyle G. Kroeck, Logan D. Andrews, John E. Knox, D. Shoun, Frederick Cohen, Emmanuel W. Smith
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
The lipid A biosynthesis pathway is essential in Pseudomonas aeruginosa. LpxA and LpxD are the first and third enzymes in this pathway respectively, and are regarded as promising antibiotic targets. The unique structural similarities between these tw
Publikováno v:
J Vis Exp
Protein-protein interactions in cell membrane systems play crucial roles in a wide range of biological processes- from cell-to-cell interactions to signal transduction; from sensing environmental signals to biological response; from metabolic regulat
Publikováno v:
Antimicrob Agents Chemother
The prevalence of multidrug-resistant Pseudomonas aeruginosa has led to the reexamination of older “forgotten” drugs, such as temocillin, for their ability to combat resistant microbes. Temocillin is the 6-α-methoxy analogue of ticarcillin, a ca
Autor:
Natasha A. Moussouras, Yu Chen, Emmanuel W. Smith, Christopher T. Veldkamp, Brian F. Volkman, Kyle G. Kroeck, Eric M. Lewandowski
Publikováno v:
Biochemistry. 55:5746-5753
CCL21 chemokine binds the G protein-coupled receptor CCR7, aiding not only in immune response but also in cancer metastasis. Compared with other chemokines, CCL21 has a unique extended unstructured C-terminus that is truncated in some naturally occur
Autor:
Vladimir N. Uversky, Boris Y. Zaslavsky, Sergei E. Permyakov, Leonid Breydo, Marina P. Shevelyova, Amanda Emmanuelle Sales, Luisa A. Ferreira, Kyle G. Kroeck, Olga Fedotoff, Eugene A. Permyakov
Publikováno v:
Archives of Biochemistry and Biophysics. 570:66-74
We analyzed the effect of a natural osmolyte, trimethylamine N-oxide (TMAO), on structural properties and conformational stabilities of several proteins under macromolecular crowding conditions by a set of biophysical techniques. We also used the sol
Autor:
Lyonna F. Alcantara, Carlos A. Bolaños-Guzmán, Kyle G. Kroeck, Brandon L. Warren, Roey Hadad, Sergio D. Iñiguez, Omar K. Sial, Katherine N. Wright, Eric M. Parise
Publikováno v:
Biological Psychiatry. 74:750-759
Background Major depressive disorder afflicts up to 10% of adolescents. However, nearly 50% of those afflicted are considered nonresponsive to available treatments. Ketamine, a noncompetitive N -methyl-D-aspartate receptor antagonist has shown potent