Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kyle E. Murphy"'
Autor:
Kyle E. Murphy, Jessica L. Bocanegra, Xiaoxi Liu, H.-Y. Katharine Chau, Patrick C. Lee, Jianing Li, Severin T. Schneebeli
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Regioselectivity during electrophilic aromatic substitution is typically controlled by substituents on the aryl group. Here the authors report an electrophilic aromatic substitution reaction, wherein remote chiral ester groups direct the electrophile
Externí odkaz:
https://doaj.org/article/cb1c33951f5949f3945f2056f03c8208
Autor:
Kyle E. Murphy, Kyle T. McKay, Mica Schenkelberg, Mona Sharafi, Olav Vestrheim, Monika Ivancic, Jianing Li, Severin T. Schneebeli
Publikováno v:
Angewandte Chemie International Edition. 61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b2521265610837035a850a07d7dcf39
https://doi.org/10.1002/anie.202216584
https://doi.org/10.1002/anie.202216584
Autor:
Kyle E. Murphy, Kyle T. McKay, Mica Schenkelberg, Mona Sharafi, Olav Vestrheim, Monika Ivancic, Jianing Li, Severin T. Schneebeli
Publikováno v:
Angewandte Chemie. 134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b167f9a7b19230d0432d189ebe3e7bc1
https://doi.org/10.1002/ange.202216584
https://doi.org/10.1002/ange.202216584
Autor:
Bryce A. Pugh, Aliyah B. Rao, Michelle Angeles-Solano, Melinda R. Grosser, John W. Brock, Kyle E. Murphy, Amanda L. Wolfe
Publikováno v:
RSC Med Chem
Antibiotic resistance has been a growing public health crisis since the 1980s. Therefore, it is essential not only to continue to develop novel antibiotics but also to develop new methods for overcoming resistance mechanisms in pathogenic bacteria so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::933b1a73c88047c7ef84409a75a91f2a
https://europepmc.org/articles/PMC9491355/
https://europepmc.org/articles/PMC9491355/
Autor:
Kyle E. Murphy, Kyle T. McKay, Mica Schenkelberg, Mona Sharafi, Olav Vestrheim, Monika Ivancic, Jianing Li, Severin T. Schneebeli
Publikováno v:
Angewandte Chemie (International ed. in English). 61(50)
We report a general synthetic route toward helical ladder polymers with varying spring constants, built with chirality-assisted synthesis (CAS). Under tension and compression, these shape-persistent structures do not unfold, but rather stretch and co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::453e38b536382910eccc7cda9f5ea487
https://pubmed.ncbi.nlm.nih.gov/36161747
https://pubmed.ncbi.nlm.nih.gov/36161747
Autor:
Mona Sharafi, Joseph P. Campbell, Kyle E. Murphy, Reilly Osadchey Brown, Severin T. Schneebeli
Publikováno v:
Synlett. 32:229-234
Electrophilic aromatic substitution reactions are of profound importance for the synthesis of biologically active compounds and other advanced materials. They represent an important means to activate specific aromatic C–H bonds without requiring tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d80d86017ac260e2ca6f99326f06e1e
https://doi.org/10.1055/s-0040-1707296
https://doi.org/10.1055/s-0040-1707296
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 75:128955
Empetroxepins A and B, which are 10,11-dihydrodibenz[b,f]oxepins produced by the Black Crowberry (Empetrum nigrum), displayed weak anti-tubercular activity upon isolation, but have not been explored for antibiotic activity despite their molecular sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91accee432f13099eb746f2a4dd36ef
https://doi.org/10.1016/j.bmcl.2022.128955
https://doi.org/10.1016/j.bmcl.2022.128955
Autor:
Severin T. Schneebeli, Kyle E. Murphy, Jessica L. Bocanegra, Joseph P. Campbell, Mona Sharafi
Publikováno v:
Supramolecular Chemistry. 31:565-574
This account describes the latest developments in the field of chirality-assisted synthesis (CAS). CAS has emerged as a versatile method to control the shapes of π-conjugated macromolecules...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2c7d7519ea86e86ce3d3ed72d08f17d
https://doi.org/10.1080/10610278.2019.1638922
https://doi.org/10.1080/10610278.2019.1638922
Autor:
Grace E Volk, Jacob T. Shumate, Amanda L. Wolfe, Grace V Lawhern, Kyle E Murphy, Grace F Sloan
Publikováno v:
Future medicinal chemistry. 12(22)
Antibiotic drug discovery has been an essential field of research since the early 1900s, but the threat from infectious bacteria has only increased over the decades because of the emergence of widespread multidrug resistance. In this review, we discu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676c5f7dbaae487c54fcf2dccca6e7b4
https://pubmed.ncbi.nlm.nih.gov/33124460
https://pubmed.ncbi.nlm.nih.gov/33124460
Autor:
Severin T. Schneebeli, Kyle E. Murphy, Jianing Li, Patrick C. Lee, Xiaoxi Liu, H-Y Katharine Chau, Jessica L. Bocanegra
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Nature Communications
Nature Communications
Nature has evolved selective enzymes for the efficient biosynthesis of complex products. This exceptional ability stems from adapted enzymatic pockets, which geometrically constrain reactants and stabilize specific reactive intermediates by placing e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b8928e6d18d1025d77891bfe528b84
https://doaj.org/article/cb1c33951f5949f3945f2056f03c8208
https://doaj.org/article/cb1c33951f5949f3945f2056f03c8208