Zobrazeno 1 - 10 of 139 pro vyhledávání: '"Kyle E. Brown"'
1
Akademický článek
A thorny matter: Spur cell anemia
Autor: Ruchi Sharma, Carol J. Holman, Kyle E. Brown
Publikováno v: Annals of Hepatology, Vol 28, Iss 1, Pp 100771- (2023)
Spur cell anemia (SCA) is an acquired form of non-autoimmune hemolytic anemia that occurs in advanced liver disease. It is characterized by the presence of acanthocytes or spur cells, spiculated erythrocytes whose shortened life span causes anemia th
Externí odkaz: https://doaj.org/article/60b224bf94864e8fb091730d36b7dd46
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2
Akademický článek
Iron-Induced Liver Injury: A Critical Reappraisal
Autor: Steven A. Bloomer, Kyle E. Brown
Publikováno v: International Journal of Molecular Sciences, Vol 20, Iss 9, p 2132 (2019)
Iron is implicated in the pathogenesis of a number of human liver diseases. Hereditary hemochromatosis is the classical example of a liver disease caused by iron, but iron is commonly believed to contribute to the progression of other forms of chroni
Externí odkaz: https://doaj.org/article/7e71352637c2451ea9b0c3e326f9e36b
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3
Spleen size change after hepatitis C treatment: a simple parameter to predict clinical outcomes
Autor: Shahana Prakash, Kyle Kinder, Kyle E Brown
Publikováno v: Journal of Investigative Medicine. :108155892311714
Portal hypertension contributes to splenomegaly in cirrhotic patients. Reduction in spleen size may represent improvement in portal hypertension. The goal was to determine whether reduction in spleen size following sustained virologic response (SVR)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f68ec7ffeb2088fad9c38b15ab02487f
https://doi.org/10.1177/10815589231171403
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6
Akademický článek
Maintenance of mitochondrial genomic integrity in the absence of manganese superoxide dismutase in mouse liver hepatocytes
Autor: Anthony R. Cyr, Kyle E. Brown, Michael L. McCormick, Mitchell C. Coleman, Adam J. Case, George S. Watts, Bernard W. Futscher, Douglas R. Spitz, Frederick E. Domann
Publikováno v: Redox Biology, Vol 1, Iss 1, Pp 172-177 (2013)
Manganese superoxide dismutase, encoded by the Sod2 gene, is a ubiquitously expressed mitochondrial antioxidant enzyme that is essential for mammalian life. Mice born with constitutive genetic knockout of Sod2 do not survive the neonatal stage, which
Externí odkaz: https://doaj.org/article/c9037b6c09df4d27bba4200983eefe20
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7
Viral eradication restores normal iron status in chronic hepatitis C patients with abnormal iron studies
Autor: Kyle E. Brown, Yazan Hasan
Publikováno v: Annals of Hepatology, Vol 19, Iss 4, Pp 422-426 (2020)
Introduction and objectives: Abnormal serum iron studies are seen in a third or more of patients with chronic hepatitis C infection (HCV), where they have been linked to accelerated fibrosis progression and increased risk of hepatocellular carcinoma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f88d72c2951688f6a44b9729af04fd61
http://www.sciencedirect.com/science/article/pii/S1665268120300247
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10
Aging results in accumulation of M1 and M2 hepatic macrophages and a differential response to gadolinium chloride
Autor: Steven A. Bloomer, Eric D. Moyer, Kevin C. Kregel, Kyle E. Brown
Publikováno v: Histochemistry and Cell Biology. 153:37-48
Macrophages have vital roles in innate immunity by modulating the inflammatory response via their ability to alter their phenotype from pro-inflammatory (M1) to anti-inflammatory (M2). Aging increases activation of the innate immune system, and macro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd3a57ece2177619221001da4a4d7095
https://doi.org/10.1007/s00418-019-01827-y
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