Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kyle D. Gibbs"'
Autor:
Taylor A. Stepien, Larissa A. Singletary, Fermin E. Guerra, Joyce E. Karlinsey, Stephen J. Libby, Sarah L. Jaslow, Margaret R. Gaggioli, Kyle D. Gibbs, Dennis C. Ko, Michael A. Brehm, Dale L. Greiner, Leonard D. Shultz, Ferric C. Fang
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTSalmonella serovars Typhi and Paratyphi cause a prolonged illness known as enteric fever, whereas other serovars cause acute gastroenteritis. Mechanisms responsible for the divergent clinical manifestations of nontyphoidal and enteric fever S
Externí odkaz:
https://doaj.org/article/557b291ef5774526961df87681eb966d
Autor:
Alejandro L. Antonia, Kyle D. Gibbs, Esme D. Trahair, Kelly J. Pittman, Amelia T. Martin, Benjamin H. Schott, Jeffrey S. Smith, Sudarshan Rajagopal, J. Will Thompson, Richard Lee Reinhardt, Dennis C. Ko
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Clearance of intracellular pathogens, such as Leishmania (L.) major, depends on an immune response with well-regulated cytokine signaling. Here we describe a pathogen-mediated mechanism of evading CXCL10, a chemokine with diverse antimicrobial functi
Externí odkaz:
https://doaj.org/article/efb2ea97a83f446aaa4e38318def991a
Publikováno v:
Annual Review of Genetics. 56:41-62
Since the identification of sickle cell trait as a heritable form of resistance to malaria, candidate gene studies, linkage analysis paired with sequencing, and genome-wide association (GWA) studies have revealed many examples of genetic resistance a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70599a4eee1071ce0092e67cc6f6097b
https://doi.org/10.1146/annurev-genet-080320-010449
https://doi.org/10.1146/annurev-genet-080320-010449
Autor:
Kyle D. Gibbs, Liuyang Wang, Zhuo Yang, Caroline E. Anderson, Jeffrey S. Bourgeois, Yanlu Cao, Margaret R. Gaggioli, Martin Biel, Rosa Puertollano, Cheng-Chang Chen, Dennis C. Ko
Publikováno v:
Cell Genomics. 3:100290
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a550dc4f2eb650826b7253c4f8b9112
https://doi.org/10.1016/j.xgen.2023.100290
https://doi.org/10.1016/j.xgen.2023.100290
Autor:
Kyle D. Gibbs, Liuyang Wang, Caroline E. Anderson, Jeffrey S. Bourgeois, Yanlu Cao, Margaret R. Gaggioli, Rosa Puertollano, Dennis C. Ko
Human genetic diversity can reveal critical factors in host-pathogen interactions. This is especially useful for human-restricted pathogens like Salmonella enterica serovar Typhi (S. Typhi), the cause of Typhoid fever. One key dynamic during infectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9385da8b262e6d344da6f5edd03af05
https://doi.org/10.1101/2022.05.08.491078
https://doi.org/10.1101/2022.05.08.491078
Autor:
Kelly J. Pittman, Alejandro L. Antonia, Esme D. Trahair, Alyson B. Barnes, Jeffrey S. Smith, J. W. Thompson, Kyle D. Gibbs, Dennis C. Ko, Richard Lee Reinhardt, Sudarshan Rajagopal, Monica I. Alvarez
Clearance of intracellular pathogens, such asLeishmania (L.) major, depends on a well-regulated adaptive T cell response. Here we describe a pathogen-encoded mechanism to alter T cell recruitment by suppressing CXCL10, a chemokine that recruits CD4+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2f8312a0008e7227dd28b60d61055b1
Autor:
Matthew W. Foster, Richard G. Brennan, Kyle D. Gibbs, Jeffrey S. Bourgeois, Dennis C. Ko, Robyn Guo, Sarah L. Jaslow, Erica J. Washington
Publikováno v:
Cell Host Microbe
Bacteria masterfully co-opt and subvert host signal transduction. As a paradigmatic example, Salmonella uses two type-3 secretion systems to inject effector proteins that facilitate Salmonella entry, establishment of an intracellular niche, and modul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115c182561cc24d4307af21cab18f7fd
https://doi.org/10.2139/ssrn.3434723
https://doi.org/10.2139/ssrn.3434723
Autor:
Stacy M. Horner, Jeffrey R. Barker, Soo Chan Lee, Robert J. Carroll, Mark R. DeLong, Joseph Heitman, Liuyang Wang, Kelly J. Pittman, Joshua C. Denny, Kyle D. Gibbs, Graham D. Williams, Tom Balmat, Anusha M. Gopalakrishnan, Andy Ingham, Alejandro L. Antonia, Dennis C. Ko, Raphael H. Valdivia, Ian B. Stanaway, David R. Crosslin, Gail P. Jarvik, Raul E. Salinas
Pathogens have been a strong driving force for natural selection. Therefore, understanding how human genetic differences impact infection-related cellular traits can mechanistically link genetic variation to disease susceptibility. Here we report the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a49984067e0e672b643409f84b457bc
https://europepmc.org/articles/PMC6093297/
https://europepmc.org/articles/PMC6093297/
Autor:
Johanna R. Elfenbein, Joshua T. Thaden, Mark K. Mammel, Kyle D. Gibbs, Liuyang Wang, W. Florian Fricke, Dennis C. Ko, Sarah L. Jaslow, Kelly J. Pittman, Gianna E. Hammer, Vance G. Fowler
Publikováno v:
Cell reports. 23(12)
Summary Salmonella enterica is an important foodborne pathogen that uses secreted effector proteins to manipulate host pathways to facilitate survival and dissemination. Different S. enterica serovars cause disease syndromes ranging from gastroenteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f782e1c4d4cb9b00a11ffa822bc80b
https://pubmed.ncbi.nlm.nih.gov/29924996
https://pubmed.ncbi.nlm.nih.gov/29924996