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pro vyhledávání: '"Kyle D. Apley"'
Autor:
Kyle D. Apley, Stephanie N. Johnson, Brandon J. DeKosky, Cory Berkland, Noora Batrash, Amy D. Laflin, J. Daniel Griffin
Publikováno v:
Industrial & Engineering Chemistry Research. 60:16839-16853
Fc fusions are a growing class of drugs comprising an antibody Fc domain covalently linked to a protein or peptide and can pose manufacturing challenges. In this study we evaluated three synthetic ...
Autor:
Aric Huang, Suresh E. Kurhade, Patrick Ross, Kyle D. Apley, Jonathan Daniel Griffin, Cory J. Berkland, Mark P. Farrell
Publikováno v:
ACS pharmacologytranslational science. 5(11)
Kifunensine is a known inhibitor of type I α-mannosidase enzymes and has been shown to have therapeutic potential for a variety of diseases and application in the expression of high-mannose N-glycan bearing glycoproteins; however, the compound's hyd
Publikováno v:
Journal of visualized experiments : JoVE. (164)
Fluorescent antigen production is a critical step in the identification of antigen-specific B cells. Here, we detailed the preparation, purification, and the use of four-arm, fluorescent PEG-antigen conjugates to selectively identify antigen-specific