Výsledky vyhledávání - "Kyle C A Wedgwood"

Akademický článek

Cardiopulmonary responses to maximal aerobic exercise in patients with cystic fibrosis.

Autor: Craig A Williams, Kyle C A Wedgwood, Hossein Mohammadi, Katie Prouse, Owen W Tomlinson, Krasimira Tsaneva-Atanasova

Publikováno v: PLoS ONE, Vol 14, Iss 2, p e0211219 (2019)

Cystic fibrosis (CF) is a debilitating chronic condition, which requires complex and expensive disease management. Exercise has now been recognised as a critical factor in improving health and quality of life in patients with CF. Hence, cardiopulmona

Externí odkaz: https://doaj.org/article/1a03b3421bb345c98ea9ef873e9debfd

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Akademický článek

Strong coupling yields abrupt synchronization transitions in coupled oscillators

Autor: Jorge L. Ocampo-Espindola, István Z. Kiss, Christian Bick, Kyle C. A. Wedgwood

Publikováno v: Physical Review Research, Vol 6, Iss 3, p 033328 (2024)

Coupled oscillator networks often display transitions between qualitatively different phase-locked solutions—such as synchrony and rotating wave solutions—following perturbation or parameter variation. In the limit of weak coupling, these transit

Externí odkaz: https://doaj.org/article/1b8c7dbd2e9041799e1c55a8d0ee1ad2

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Inferring parameters of pyramidal neuron excitability in mouse models of Alzheimer’s disease using biophysical modeling and deep learning

Autor: Soheil Saghafi, Timothy Rumbell, Viatcheslav Gurev, James Kozloski, Francesco Tamagnini, Kyle C. A. Wedgwood, Casey O. Diekman

Alzheimer’s disease (AD) is believed to occur when abnormal amounts of the proteins amyloid beta and tau aggregate in the brain, resulting in a progressive loss of neuronal function. Hippocampal neurons in transgenic mice with amyloidopathy or tauo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c68b4c528bb6bc505a176add7ca4e83d
https://doi.org/10.1101/2023.04.18.537149

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Spatial distribution of heterogeneity as a modulator of collective dynamics in pancreatic beta-cell networks and beyond

Autor: Daniel Galvis, David J. Hodson, Kyle C. A. Wedgwood

Publikováno v: Frontiers in Network Physiology. 3

We study the impact of spatial distribution of heterogeneity on collective dynamics in gap-junction coupled beta-cell networks comprised on cells from two populations that differ in their intrinsic excitability. Initially, these populations are unifo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::72cbd9c27e132a161a54ab206904017b
https://doi.org/10.3389/fnetp.2023.1170930

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