Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kyle Beckman"'
Autor:
Holly Pariury, Joshua Fandel, Stefanie Bachl, Kenny K. Ang, Sarine Markossian, Chris G. Wilson, Benjamin S. Braun, Bogdan Popescu, Margo Wohlfeil, Kyle Beckman, Simayijiang Xirenayi, Ritu P. Roy, Adam B. Olshen, Catherine Smith, Michelle R. Arkin, Mignon L. Loh, Ernesto Diaz-Flores
Publikováno v:
Haematologica, Vol 108, Iss 5 (2023)
Hypodiploid acute lymphoblastic leukemia (ALL) is an aggressive blood cancer with a poor prognosis despite intensive chemotherapy or stem cell transplant. Children and adolescents with positive end-of-induction minimal residual disease have an overal
Externí odkaz:
https://doaj.org/article/fded8a4dea2a4fc79e14f5bf9407a19e
Autor:
Mignon L. Loh, Charles G. Mullighan, Benjamin S. Braun, Margo Wohlfeil, Roberta Marino, Olga Bridges, Jon Akutagawa, Kevin Wu, Kara L. Davis, Kyle Beckman, Ella Melnik, Kailyn L. Kim, Evan Q. Comeaux, Ernesto Diaz-Flores
Acute lymphoblastic leukemia (ALL) is the most common cancer in children. The highest rates of treatment failure occur in specific genetic subsets of ALL, including hypodiploid B-cell ALL (B-ALL), for which effective alternative therapies to current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61495c1a32fb1f6588c46c4ae6a2ce7f
https://doi.org/10.1158/0008-5472.c.6511406.v1
https://doi.org/10.1158/0008-5472.c.6511406.v1
Autor:
Mignon L. Loh, Charles G. Mullighan, Benjamin S. Braun, Margo Wohlfeil, Roberta Marino, Olga Bridges, Jon Akutagawa, Kevin Wu, Kara L. Davis, Kyle Beckman, Ella Melnik, Kailyn L. Kim, Evan Q. Comeaux, Ernesto Diaz-Flores
Legends for each supplementary figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442917b0069ac958fcc79abdf729aef7
https://doi.org/10.1158/0008-5472.22423028
https://doi.org/10.1158/0008-5472.22423028
Autor:
Mignon L. Loh, Charles G. Mullighan, Benjamin S. Braun, Margo Wohlfeil, Roberta Marino, Olga Bridges, Jon Akutagawa, Kevin Wu, Kara L. Davis, Kyle Beckman, Ella Melnik, Kailyn L. Kim, Evan Q. Comeaux, Ernesto Diaz-Flores
Supplemental Figure 1. Protein and gene expression profiling of hypodiploid ALL. Supplemental Figure 2. Pairing biochemical characterization with viability/survival assays in hypodiploid B-ALL. Supplemental Figure 3. Primagraft samples used for ex vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f750859113f5abccbd2e5b76ce3a75c7
https://doi.org/10.1158/0008-5472.22423031
https://doi.org/10.1158/0008-5472.22423031
Autor:
Sara Seepo, Kyle Beckman, Clifford M. Takemoto, Todd Cooper, Johann Hitzler, Philip A. Roehrs, Todd R. Golub, Tiffany Y. Chang, Scott R. Olsen, Tali Mazor, Patrick A. Brown, Robert J. Hayashi, Mara Rosenberg, Reuven J. Schore, Rakesh K. Goyal, Philip M. Monteleone, Emilio Esquivel, Jeffrey A. Toretsky, Elliot Stieglitz, Robert B. Gerbing, Mignon L. Loh, Adam B. Olshen, Gad Getz, Yong Dong Wang, Yongjin Li, Benjamin Carcamo, Laura C. Gelston, Kimo C. Stine, Ghada Abusin, Chip Stewart, Peter D. Emanuel, Todd A. Alonzo, Y. Lucy Liu, Yoav Messinger, Gary V. Dahl, Joseph F. Costello, Kimberly Stegmaier, Christopher Hugge, Donald H. Mahoney, Jing Ma, Eneida R. Nemecek, Sophie Archambeault, Amaro Taylor-Weiner, Ariel Yu, Mark Fluchel, Tanja A. Gruber, Michael Briones
Publikováno v:
Nature genetics
Juvenile myelomonocytic leukemia (JMML) is a myeloproliferative neoplasm (MPN) of childhood with a poor prognosis. Mutations in NF1, NRAS, KRAS, PTPN11 and CBL occur in 85% of patients, yet there are currently no risk stratification algorithms capabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8865d5d13f14756a5f9ec0e886b02ab9
https://doi.org/10.1038/ng.3400
https://doi.org/10.1038/ng.3400
Autor:
Adam R. Abate, Eric D. Chow, Elliot Stieglitz, Y. Lucy Liu, John R. Haliburton, Camille B. Troup, Todd A. Alonzo, Yong-Dong Wang, Kyle Beckman, Amaro Taylor-Weiner, Mignon L. Loh, Robert B. Gerbing, Benjamin S. Braun, Peter D. Emanuel, Laura C. Gelston, Kristie B. Yu, Jon Akutagawa
Publikováno v:
Blood. 125(3)
Juvenile myelomonocytic leukemia (JMML) is an aggressive myeloproliferative neoplasm of childhood associated with a poor prognosis. Recently, massively parallel sequencing has identified recurrent mutations in the SKI domain of SETBP1 in a variety of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e2e2a52f112627d19b64c4d4efdf51c
https://pubmed.ncbi.nlm.nih.gov/25395418
https://pubmed.ncbi.nlm.nih.gov/25395418
Autor:
Linda Holmfeldt, Charles G. Mullighan, Kara L. Davis, Evan Q. Comeaux, Mignon L. Loh, Jon Akutagawa, Kyle Beckman, Kevin J. Wu, Kailyn L Kim, Benjamin S. Braun, Ernesto Diaz-Flores
Publikováno v:
Blood. 128:280-280
Acute lymphoblastic leukemia (ALL) is the most common cancer of childhood. Specific genetic subsets, including hypodiploid ALL, are associated with particularly high rates of relapse. Despite the poor outcomes of hypodiploid B-ALL with traditional th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::457653f63c0b680314f3b72a3f04c8e9
https://doi.org/10.1182/blood.v128.22.280.280
https://doi.org/10.1182/blood.v128.22.280.280
Autor:
Clifford M. Takemoto, Elliot Stieglitz, Yoav H. Messinger, Michael Briones, Tiffany Y. Chang, Kimberly Stegmaier, Philip M. Monteleone, Ghada Abusin, Emilio Esquivel, Chip Stewart, Johann Hitzler, Sophie Archambeault, Kimo C. Stine, Ariel Yu, Tali Mazor, Mignon L. Loh, Benjamin Carcamo, Gad Getz, Joseph F. Costello, Eneida R. Nemecek, Mark Fluchel, Yong Dong Wang, Yongjin Li, Peter D. Emanuel, Christopher Hugge, Donald H. Mahoney, Jing Ma, Rakesh K. Goyal, Amaro Taylor-Weiner, Sara Seepo, Mara Rosenberg, Robert B. Gerbing, Kyle Beckman, Scott R. Olsen, Jeffrey A. Toretsky, Adam B. Olshen, Todd R. Golub, Laura C. Gelston, Todd A. Alonzo, Philip A. Roehrs, Robert J. Hayashi, Y. Lucy Liu, Tanja A. Gruber, Gary V. Dahl, Todd M. Cooper, Reuven J. Schore, Patrick A. Brown
Publikováno v:
Nature Genetics. 48:101-101
Nat. Genet. 47, 1326–1333 (2015); published online 12 October 2015; corrected after print 7 December 2015 In the version of this article initially published, two patients were stated on page 5 to have been excluded owing to insufficient follow-up d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bff0cc2e1b6c0521e2c1075ca83525b2
https://doi.org/10.1038/ng0116-101a
https://doi.org/10.1038/ng0116-101a