Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kyle B. Spainhower"'
Autor:
Gary Wildey, Ashley M. Shay, Karen S. McColl, Suzy Yoon, Mohammad A. Shatat, Ahmad Perwez, Kyle B. Spainhower, Adam M. Kresak, MaryBeth Lipka, Michael Yang, Mohadese Behtaj, Pingfu Fu, Asrar Alahmadi, Wadad Mneimneh, Ata Abbas, Afshin Dowlati
Publikováno v:
Molecular Cancer Therapeutics. 22:264-273
The canonical model of “small cell lung cancer” (SCLC) depicts tumors arising from dual inactivation of TP53 and RB1. However, many genomic studies have persistently identified tumors with no RB1 mutations. Here, we examined RB1 protein expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4c86a83b730dfa552956cd55e68734
https://doi.org/10.1158/1535-7163.mct-22-0365
https://doi.org/10.1158/1535-7163.mct-22-0365
Autor:
Demetra P. Kelenis, Kathia E. Rodarte, Rahul K. Kollipara, Karine Pozo, Shreoshi Pal Choudhuri, Kyle B. Spainhower, Sarah J. Wait, Victor Stastny, Trudy G. Oliver, Jane E. Johnson
Publikováno v:
Cancer Res
Genomic studies support the classification of small cell lung cancer (SCLC) into subtypes based on the expression of lineage-defining transcription factors ASCL1 and NEUROD1, which together are expressed in ∼86% of SCLC. ASCL1 and NEUROD1 activate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88611bcc0dc0a9f25a76be3967ef6521
https://doi.org/10.1158/0008-5472.can-21-3713
https://doi.org/10.1158/0008-5472.can-21-3713
Autor:
Charles M. Rudin, Thales Papagiannakopoulos, John T. Poirier, Trudy G. Oliver, Triparna Sen, Mark T.A. Donoghue, Tyler Jacks, Elliot H. Akama-Garren, William M. Rideout, Andrea Ventura, Danilo Maddalo, Anastasia-Maria Zavitsanou, Janneke E. Jaspers, Francisco J. Sanchez-Rivera, Faruk E. Kombak, Kyle B. Spainhower, Parvathy Manoj, Viola Allaj, Emily A. Costa, Rebecca Caeser, Angeliki Karatza, Àlvaro Quintanal-Villalonga, Allison L. Richards, Triantafyllia Karakousi, Metamia Ciampricotti
Supplementary Figures S1 - S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e21dac3fbf8c8abfbd8d681c0ce639
https://doi.org/10.1158/2159-8290.22540609
https://doi.org/10.1158/2159-8290.22540609
Autor:
Afshin Dowlati, Ata Abbas, Wadad Mneimneh, Asrar Alahmadi, Pingfu Fu, Mohadese Behtaj, Michael Yang, MaryBeth Lipka, Adam M. Kresak, Kyle B. Spainhower, Ahmad Perwez, Mohammad A. Shatat, Suzy Yoon, Karen S. McColl, Ashley M. Shay, Gary Wildey
Supplementary Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c1f7d4df3b05d341bd589cf3a47e758
https://doi.org/10.1158/1535-7163.22523419.v1
https://doi.org/10.1158/1535-7163.22523419.v1
Autor:
Afshin Dowlati, Ata Abbas, Wadad Mneimneh, Asrar Alahmadi, Pingfu Fu, Mohadese Behtaj, Michael Yang, MaryBeth Lipka, Adam M. Kresak, Kyle B. Spainhower, Ahmad Perwez, Mohammad A. Shatat, Suzy Yoon, Karen S. McColl, Ashley M. Shay, Gary Wildey
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525650c2b519933fc2330b6b23a033e0
https://doi.org/10.1158/1535-7163.22523413.v1
https://doi.org/10.1158/1535-7163.22523413.v1
Autor:
Charles M. Rudin, Thales Papagiannakopoulos, John T. Poirier, Trudy G. Oliver, Triparna Sen, Mark T.A. Donoghue, Tyler Jacks, Elliot H. Akama-Garren, William M. Rideout, Andrea Ventura, Danilo Maddalo, Anastasia-Maria Zavitsanou, Janneke E. Jaspers, Francisco J. Sanchez-Rivera, Faruk E. Kombak, Kyle B. Spainhower, Parvathy Manoj, Viola Allaj, Emily A. Costa, Rebecca Caeser, Angeliki Karatza, Àlvaro Quintanal-Villalonga, Allison L. Richards, Triantafyllia Karakousi, Metamia Ciampricotti
Small cell lung cancer (SCLC) has limited therapeutic options and an exceptionally poor prognosis. Understanding the oncogenic drivers of SCLC may help define novel therapeutic targets. Recurrent genomic rearrangements have been identified in SCLC, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e119dfd0f00e496d01bd3fbdec93d54
https://doi.org/10.1158/2159-8290.c.6549427.v1
https://doi.org/10.1158/2159-8290.c.6549427.v1
Autor:
Jane E. Johnson, Trudy G. Oliver, Victor Stastny, Sarah J. Wait, Kyle B. Spainhower, Shreoshi Pal Choudhuri, Karine Pozo, Rahul K. Kollipara, Kathia E. Rodarte, Demetra P. Kelenis
Supplementary Figure from Inhibition of Karyopherin β1-Mediated Nuclear Import Disrupts Oncogenic Lineage-Defining Transcription Factor Activity in Small Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f77480f7d86cec73f1e64d9bc5eff7f
https://doi.org/10.1158/0008-5472.22431816.v1
https://doi.org/10.1158/0008-5472.22431816.v1
Autor:
Jane E. Johnson, Trudy G. Oliver, Victor Stastny, Sarah J. Wait, Kyle B. Spainhower, Shreoshi Pal Choudhuri, Karine Pozo, Rahul K. Kollipara, Kathia E. Rodarte, Demetra P. Kelenis
Genomic studies support the classification of small cell lung cancer (SCLC) into subtypes based on the expression of lineage-defining transcription factors ASCL1 and NEUROD1, which together are expressed in ∼86% of SCLC. ASCL1 and NEUROD1 activate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8470d5df0b24ad6cd9d25425597d5fa5
https://doi.org/10.1158/0008-5472.c.6513996
https://doi.org/10.1158/0008-5472.c.6513996
Autor:
Jane E. Johnson, Trudy G. Oliver, Victor Stastny, Sarah J. Wait, Kyle B. Spainhower, Shreoshi Pal Choudhuri, Karine Pozo, Rahul K. Kollipara, Kathia E. Rodarte, Demetra P. Kelenis
Supplementary Table from Inhibition of Karyopherin β1-Mediated Nuclear Import Disrupts Oncogenic Lineage-Defining Transcription Factor Activity in Small Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ff3a62d6b73cfa5452e03cfed347e4
https://doi.org/10.1158/0008-5472.22431810
https://doi.org/10.1158/0008-5472.22431810
Autor:
Michael T. Butcher, Brandon T. Sinn, Sarah K. Marshall, Thomas P. Diggins, Kyle B. Spainhower
Publikováno v:
Journal of Mammalian Evolution. 28:599-619
Divergence in forelimb morphology is often associated with functional habits exhibited within the Xenarthra, ranging from terrestrial-digging in armadillos to arboreal-suspension in sloths. We hypothesized that quantitative differences in hind limb f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e39e77ab98f5b5b4e17aa606f901d830
https://doi.org/10.1007/s10914-021-09537-w
https://doi.org/10.1007/s10914-021-09537-w