Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kyle B. Kener"'
Autor:
MaryJane Sampson, Daniel R. Lathen, Blake W. Dallon, Carrie Draney, Jason D. Ray, Kyle B. Kener, Brian A. Parker, Jonathan L. Gibbs, Jarom S. Gropp, Jeffery S. Tessem, Benjamin T. Bikman
Publikováno v:
Journal of Metabolic Health, Vol 2, Iss 1, Pp e1-e8 (2017)
Pharmacological interventions aimed at improving outcomes in type 2 diabetes and achieving normoglycaemia, including insulin therapy, are increasingly common, despite the potential for substantial side effects. Carbohydrate-restricted diets that resu
Externí odkaz:
https://doaj.org/article/4555a5fe1f4d40fc8104ec2e43596b46
Autor:
Courtney J. Smith, Jeffery S. Tessem, Kyle B. Kener, Adam G. Wynn, Matthew C. Austin, Jacob A. Herring
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38af520c118d11366aba448b6f68d3c5
https://doi.org/10.1096/fasebj.2019.33.1_supplement.487.7
https://doi.org/10.1096/fasebj.2019.33.1_supplement.487.7
Publikováno v:
Diabetes. 67
We have shown that the orphan nuclear receptors Nr4a1 and Nr4a3 are critical for beta cell mitochondrial respiration and fuel utilization, and that loss of either factor impedes fuel utilization and insulin secretion. We have also demonstrated that p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b225f900552b2212bbc11a5228e2e0da
https://doi.org/10.2337/db18-2040-p
https://doi.org/10.2337/db18-2040-p
Autor:
Kyle B. Kener, Aaron H. Leifer, Amanda Haines, Jeffery S. Tessem, Courtney J. Smith, Patrick T. Fueger, Kavan H. Hess, Angelina Hernandez-Carretero, Michelle Arlotto, Lanair A. Lett, Carrie Draney, Matthew C. Austin, Talon J. Aitken
Publikováno v:
The Biochemical journal. 475(24)
The homeobox transcription factor Nkx6.1 is sufficient to increase functional β-cell mass, where functional β-cell mass refers to the combination of β-cell proliferation, glucose-stimulated insulin secretion (GSIS) and β-cell survival. Here, we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e82da34a1daca34183a96d4b0f1623c5
https://pubmed.ncbi.nlm.nih.gov/30322885
https://pubmed.ncbi.nlm.nih.gov/30322885
Autor:
K. Scott Weber, Mitchell E. Allen, Josie A. Tueller, Matthew W. Hulver, David Brown, Deborah K. Johnson, Kyle B. Kener, Benjamin F. Bitner, Jason D. Ray, Dane W. Fausnacht, Jacob A. Herring, Andrew P. Neilson, Jeffery S. Tessem, Ryan P. McMillan, Alexander H. Thomson, Claudia M. Tellez Freitas
Publikováno v:
The Journal of nutritional biochemistry. 62
Flavonoids are dietary compounds with potential anti-diabetes activities. Many flavonoids have poor bioavailability and thus low circulating concentrations. Unabsorbed flavonoids are metabolized by the gut microbiota to smaller metabolites, which are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e6de3b53cf6d34fc7cae26be77c8ae
https://pubmed.ncbi.nlm.nih.gov/30286378
https://pubmed.ncbi.nlm.nih.gov/30286378
Autor:
Kyle B. Kener, Jeffery S. Tessem, Benjamin T. Bikman, Chad R. Hancock, Adam G. Wynn, Kevin Garland, K. Scott Weber
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66748d58a44287d217dd61b474a7d735
https://doi.org/10.1096/fasebj.2018.32.1_supplement.719.1
https://doi.org/10.1096/fasebj.2018.32.1_supplement.719.1
Autor:
Moroni Lopez, Mimi Ross, Benjamin F. Bitner, Jeffery S. Tessem, Jason D. Ray, Benjamin T. Bikman, Thomas J. Rowley, Andrew P. Neilson, Jacob A. Herring, Kyle B. Kener
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f804ae3f0438c9c99c4b7bae34b343e
https://doi.org/10.1096/fasebj.2018.32.1_supplement.41.8
https://doi.org/10.1096/fasebj.2018.32.1_supplement.41.8
Publikováno v:
Journal of Visualized Experiments.
High-resolution respirometry allows for the measurement of oxygen consumption of isolated mitochondria, cells and tissues. Beta cells play a critical role in the body by controlling blood glucose levels through insulin secretion in response to elevat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128033ee19dedecbc43bc1dacdb52742
https://doi.org/10.3791/57053-v
https://doi.org/10.3791/57053-v
Autor:
Blake W. Dallon, MaryJane Sampson, Benjamin T. Bikman, Jeffery S. Tessem, Jason D. Ray, Brian A. Parker, Carrie Draney, Kyle B. Kener, Jarom S. Gropp, Daniel R. Lathen, Jonathan L. Gibbs
Publikováno v:
Journal of Insulin Resistance, Vol 2, Iss 1, Pp e1-e8 (2017)
Pharmacological interventions aimed at improving outcomes in type 2 diabetes and achieving normoglycaemia, including insulin therapy, are increasingly common, despite the potential for substantial side effects. Carbohydrate-restricted diets that resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e47efdd564fdaa2d6bcdbb5e7f8f9f
https://doi.org/10.4102/jir.v2i1.25
https://doi.org/10.4102/jir.v2i1.25
Autor:
Kyle B. Kener, Jason D. Ray, Jeffery S. Tessem, Merrick Reynolds, Benjamin T. Bikman, Kevin Garland, Jeremy M. Hardman, Carrie Draney, Chad R. Hancock
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 311(1)
β-Cell insulin secretion is dependent on proper mitochondrial function. Various studies have clearly shown that the Nr4a family of orphan nuclear receptors is essential for fuel utilization and mitochondrial function in liver, muscle, and adipose. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a32233a61caa264eb07f8d301c0fa3d
https://pubmed.ncbi.nlm.nih.gov/27221116
https://pubmed.ncbi.nlm.nih.gov/27221116