Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kyle B Woodward"'
Autor:
Marie Bleakley, Ralph Graeme Black, David Wu, Melinda Ann Biernacki, Jessica Lok, Kimberly A Foster, Carrie Cummings, Kyle B Woodward, Tim Monahan, Vivian G Oehler, Derek L Stirewalt, Anthony Rongvaux, Hans Joachim Deeg
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 12 (2023)
Background Myelodysplastic syndromes (MDS) arise from somatic mutations acquired in hematopoietic stem and progenitor cells, causing cytopenias and predisposing to transformation into secondary acute myeloid leukemia (sAML). Recurrent mutations in sp
Externí odkaz:
https://doaj.org/article/f4118942bcee4419aa80630b09b59a98
Autor:
Kyle B. Woodward, Kimberly A. Foster, Soheil Meshinchi, Michael E. Coon, Elihu H. Estey, Tanya Cunningham, Tayla M Olsen, Kelda M. Gardner, Jamie Stokke, Melinda A. Biernacki, Robson G. Dossa, Marie Bleakley, Anthony Rongvaux, Michelle Brault, Carrie Cummings
Publikováno v:
J Clin Invest
The tight junction protein claudin-2 is upregulated in disease. Although many studies have linked intestinal barrier loss to local and systemic disease, these have relied on macromolecular probes. In vitro analyses show, however, that these probes ca
Autor:
Kyle B. Woodward, Pradeep Shrestha, Esma S. Yolcu, Hong Zhao, Haval Shirwan, Orlando Grimany-Nuno, Laura Bandura-Morgan, Lalit Batra, Nadir Askenasy, Min Tan
Publikováno v:
Am J Transplant
We have previously shown that pancreatic islets engineered to transiently display a modified form of FasL protein (SA-FasL) on their surface survive indefinitely in allogeneic recipients without a need for chronic immunosuppression. Mechanisms that c
Autor:
Marie Bleakley, Robson G. Dossa, Megan Hickner, Merav Bar, Tsadik Habtetsion, Melinda Ann Biernacki, Ann Dahlberg, Colette Chaney, Michelle Brault, Kyle B. Woodward, Nicole Vartanian, Tanya Cunningham, Corinne Summers, Elizabeth F. Krakow
Publikováno v:
Blood. 136:45-46
Background: Donor T cells specific for minor histocompatibility (H) antigens can deliver potent, selective anti-leukemic effects after allogeneic HCT when the antigen is negligibly or not expressed by non-hematopoietic tissues, not present in the don
Autor:
Kyle B. Woodward, Andrés J. García, Lonnie D. Shea, Feng Wang, Haval Shirwan, Ryan M. Pearson, Hong Zhao, Michael Skoumal, Esma S. Yolcu, Kevin R. Hughes
Intraportal allogeneic islet transplantation has been demonstrated as a potential therapy for type 1 diabetes (T1D). The placement of islets into the liver and chronic immunosuppression to control rejection are two major limitations of islet transpla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892e48b167b042b46d29a1cb962b4d6d
https://europepmc.org/articles/PMC6331284/
https://europepmc.org/articles/PMC6331284/
Autor:
Haval Shirwan, Orlando Grimany-Nuno, Lalit Batra, Min Tan, Mohammad Tariq Malik, Hong Zhao, Kyle B. Woodward, Pradeep Shrestha, Alper Togay, Maria M. Coronel, Andrés J. García, Esma S. Yolcu
Publikováno v:
Transplantation. 104:S152-S152
Conquering allograft rejection remains an elusive goal in spite of recent breakthroughs in the field of immunosuppression. Much of the problem lies in the toxicity and side-effects of long-term use of systemic immunosuppressant drugs, which are somet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b9575992f5c8bde241cf281097ad6d
https://europepmc.org/articles/PMC4701610/
https://europepmc.org/articles/PMC4701610/
Autor:
Esma S. Yolcu, Chantale Lacelle, Haval Shirwan, Kyle B. Woodward, Hong Zhao, Laura Bandura-Morgan, Nadir Askenasy
Publikováno v:
The Journal of Immunology. 187:5901-5909
Allogeneic islet transplantation is an important therapeutic approach for the treatment of type 1 diabetes. Clinical application of this approach, however, is severely curtailed by allograft rejection primarily initiated by pathogenic effector T cell
Autor:
Michael D. Hunckler, Kyle B. Woodward, Pradeep Shrestha, Jessica D. Weaver, Min Tan, William S. Bowen, Esma S. Yolcu, Andrés J. García, Maria M. Coronel, Devon M. Headen, Haval Shirwan
Publikováno v:
Transplantation. 102:S291
Autor:
Haval Shirwan, Min Tan, Lalit Batra, Kyle B. Woodward, Hong Zhao, Esma S. Yolcu, Maria M. Coronel, Andrés J. García, Pradeep Shrestha, William S. Bowen
Publikováno v:
Transplantation. 102:S455