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pro vyhledávání: '"Kyle A. Piccolo"'
Autor:
Juewen Liu, Kyle A. Piccolo, Yongqiang Kang, Runjhun Saran, Chunying Wei, Da Chen, Yanping He, Thorsten Dieckmann, Po-Jung Jimmy Huang
Publikováno v:
Canadian Journal of Chemistry. 99:860-866
Recently, a Na+-binding aptamer was reported to be embedded in a few RNA-cleaving DNAzymes, including NaA43, Ce13d, and NaH1. The Na+ aptamer consists of multiple GG stretches, which is a prerequisite for the formation of G-quadruplex (G4) structures
Autor:
W. Scott Hopkins, Kyle A. Piccolo, Thorsten Dieckmann, Brooke McNeil, Jeff Crouse, Su Ji Lim, Sarah C. Bickers
Publikováno v:
Biochemical and biophysical research communications. 529(3)
Binding affinity and selectivity are critical properties of aptamers that must be optimized for any application. The sulforhodamine B binding RNA aptamer (SRB-2) is a somewhat promiscuous aptamer that can bind ligands that vary markedly in shape, siz