Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Kyle A, O'Connell"'
Autor:
Kyle A. O’Connell, Zelaikha B. Yosufzai, Ross A. Campbell, Collin J. Lobb, Haley T. Engelken, Laura M. Gorrell, Thad B. Carlson, Josh J. Catana, Dina Mikdadi, Vivien R. Bonazzi, Juergen A. Klenk
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background As genome sequencing becomes better integrated into scientific research, government policy, and personalized medicine, the primary challenge for researchers is shifting from generating raw data to analyzing these vast datasets. Al
Externí odkaz:
https://doaj.org/article/754ff48ab5e94a3fa40fb2c075adbe3a
Autor:
L. Lee Grismer, Perry L. Wood, Jr., Nikolay A. Poyarkov, Minh D. Le, Fred Kraus, Ishan Agarwal, Paul M. Oliver, Sang N. Nguyen, Truong Q. Nguyen, Suranjan Karunarathna, Luke J. Welton, Bryan L. Stuart, Vinh Q. Luu, Aaron M. Bauer, Kyle A. O’Connell, Evan S. H. Quah, Kin O. Chan, Thomas Ziegler, Hanh Ngo, Roman A. Nazarov, Anchalee Aowphol, Siriwadee Chomdej, Chatmongkon Suwannapoom, Cameron D. Siler, Shahrul Anuar, Ngo V. Tri, Jesse L. Grismer
Publikováno v:
Vertebrate Zoology, Vol 71, Iss , Pp 101-154 (2021)
The gekkonid genus Cyrtodactylus is the third most speciose vertebrate genus in the world, containing well over 300 species that collectively range from South Asia to Melanesia across some of the most diverse landscapes and imperiled habitats on the
Externí odkaz:
https://doaj.org/article/5c548fc8615a469ba3de302647039ae9
Autor:
Robert Alexander Pyron, Kyle A. O’Connell, Emily Moriarty Lemmon, Alan R. Lemmon, David A. Beamer
Publikováno v:
Ecology and Evolution, Vol 12, Iss 2, Pp n/a-n/a (2022)
Abstract Dusky Salamanders (genus Desmognathus) currently comprise only 22 described, extant species. However, recent mitochondrial and nuclear estimates indicate the presence of up to 49 candidate species based on ecogeographic sampling. Previous st
Externí odkaz:
https://doaj.org/article/89a6c246044549dda5a7c478d382a52f
Publikováno v:
Ecology and Evolution, Vol 9, Iss 6, Pp 3620-3636 (2019)
Abstract Effective conservation and management of pond‐breeding amphibians depends on the accurate estimation of population structure, demographic parameters, and the influence of landscape features on breeding‐site connectivity. Population‐lev
Externí odkaz:
https://doaj.org/article/7528dc8e400c4314bce8417124c7596a
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 655 (2022)
With the advent of cancer immunotherapy, there has been a major improvement in patient’s quality of life and survival. The growth of cancer immunotherapy has dramatically changed our understanding of the basics of cancer biology and has altered the
Externí odkaz:
https://doaj.org/article/6932c94d40064453b8e66d159588033a
Autor:
Kyle A. O’Connell, Eric N. Smith
Publikováno v:
Data in Brief, Vol 18, Iss , Pp 1995-1999 (2018)
In this data article we present species trees based on coalescent species delimitation results for North American whipsnakes, as well as metadata pertaining to the article ''The effect of missing data on coalescent species delimitation and a taxonomi
Externí odkaz:
https://doaj.org/article/4d220efc8d4d4dcaa2c0c71688f665ed
Publikováno v:
Systematic Biology. 72:179-197
Significant advances have been made in species delimitation and numerous methods can test precisely defined models of speciation, though the synthesis of phylogeography and taxonomy is still sometimes incomplete. Emerging consensus treats distinct ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb3439624aa1acbcbe9fb4fa4195100
https://doi.org/10.1093/sysbio/syac065
https://doi.org/10.1093/sysbio/syac065
Autor:
Louis F. Chai, John C. Hardaway, Kara R. Heatherton, Kyle P. O’Connell, Mikayla C. Lopes, Benjamin A. Rabinowitz, Chandra C. Ghosh, Prajna Guha, David Jaroch, Bryan F. Cox, Steven C. Katz
Publikováno v:
Vaccines, Vol 9, Iss 8, p 807 (2021)
Metastatic liver tumors have presented challenges with the use of checkpoint inhibitors (CPIs), with only limited success. We hypothesize that regional delivery (RD) of CPIs can improve activity in the liver and minimize systemic exposure, thereby re
Externí odkaz:
https://doaj.org/article/6fb5f456cae4492f8c6c1e505c93455d
Autor:
Louis F. Chai, John C. Hardaway, Kara R. Heatherton, Kyle P. O'Connell, Jason P. LaPorte, Prajna Guha, Mikayla C. Lopes, Benjamin A. Rabinowitz, David Jaroch, Bryan F. Cox, Robert Knight, Steven C. Katz
Publikováno v:
Journal of Surgical Research. 272:37-50
Effective treatment of solid tumors requires multi-modality approaches. In many patients with stage IV liver disease, current treatments are not curative. Chimeric antigen receptor T cells (CAR-T) are an intriguing option following success in hematol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf869c95ee41bbec7c6820448937aad
https://doi.org/10.1016/j.jss.2021.11.001
https://doi.org/10.1016/j.jss.2021.11.001
Autor:
Dina, Mikdadi, Kyle A, O'Connell, Philip J, Meacham, Madeleine A, Dugan, Michael O, Ojiere, Thaddeus B, Carlson, Juergen A, Klenk
Publikováno v:
Cancer Biomarkers. 33:173-184
BACKGROUND: Artificial intelligence (AI), including machine learning (ML) and deep learning, has the potential to revolutionize biomedical research. Defined as the ability to “mimic” human intelligence by machines executing trained algorithms, AI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062308a286983c82c621e457ff6f9b99
https://doi.org/10.3233/cbm-210301
https://doi.org/10.3233/cbm-210301