Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Kyle, Rosenke"'
Autor:
Ami Patel, Kyle Rosenke, Elizabeth M. Parzych, Friederike Feldmann, Suman Bharti, Amanda J. Griffin, Blake Schouest, Matt Lewis, Jihae Choi, Neethu Chokkalingam, Viviane Machado, Brian J. Smith, Drew Frase, Ali R. Ali, Jamie Lovaglio, Brian Nguyen, Patrick W. Hanley, Susanne N. Walker, Ebony N. Gary, Abhijeet Kulkarni, Allison Generotti, Joseph R. Francica, Kim Rosenthal, Daniel W. Kulp, Mark T. Esser, Trevor R. F. Smith, Carl Shaia, David B. Weiner, Heinz Feldmann
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTCOVID-19 remains a major public health concern. Monoclonal antibodies have received emergency use authorization (EUA) for pre-exposure prophylaxis against COVID-19 among high-risk groups for treatment of mild to moderate COVID-19. In addition
Externí odkaz:
https://doaj.org/article/b981edf4969f4fdb9843528b197ac517
Autor:
Forrest Bohler, Kathleen Cashman, Eric Wilkinson, Joshua C. Johnson, Kyle Rosenke, Josh Shamblin, Lisa Hensley, Anna Honko, Carl Shaia
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Lassa virus (LASV) causes an acute multisystemic hemorrhagic fever in humans known as Lassa fever, which is endemic in several African countries. This manuscript focuses on the progression of disease in cynomolgus macaques challenged with aerosolized
Externí odkaz:
https://doaj.org/article/64ea00c679564d18bd782986357aff99
Autor:
Joshua Marceau, David Safronetz, Cynthia Martellaro, Andrea Marzi, Kyle Rosenke, Heinz Feldmann
Publikováno v:
Viruses, Vol 16, Iss 2, p 279 (2024)
Orthohantaviruses may cause hemorrhagic fever with renal syndrome or hantavirus cardiopulmonary syndrome. Andes virus (ANDV) is the only orthohantavirus associated with human–human transmission. Therefore, emergency vaccination would be a valuable
Externí odkaz:
https://doaj.org/article/51d114e90f5e4a1abcf81c7b40f785c0
Autor:
Kyle Rosenke, Matt C. Lewis, Friederike Feldmann, Eric Bohrnsen, Benjamin Schwarz, Atsushi Okumura, W. Forrest Bohler, Julie Callison, Carl Shaia, Catharine M. Bosio, Jamie Lovaglio, Greg Saturday, Michael A. Jarvis, Heinz Feldmann
Publikováno v:
JCI Insight, Vol 8, Iss 4 (2023)
The periodic emergence of SARS-CoV-2 variants of concern (VOCs) with unpredictable clinical severity and ability to escape preexisting immunity emphasizes the continued need for antiviral interventions. Two small molecule inhibitors, molnupiravir (MK
Externí odkaz:
https://doaj.org/article/8c4c6d11714643ca966ef175993be046
Histopathologic Characterization of Experimental Peracute SARS-CoV-2 Infection in the Syrian Hamster
Autor:
Chad S. Clancy, Kimberly Meade-White, Carl Shaia, Greg Saturday, Heinz Feldmann, Kyle Rosenke
Publikováno v:
Veterinary Sciences, Vol 10, Iss 9, p 536 (2023)
Coronavirus Infectious Disease 2019 (COVID-19) initiated a global pandemic that thus far has resulted in the death of over 6.5 million people internationally. Understanding the viral tropism during the initial, subclinical phase of infection is criti
Externí odkaz:
https://doaj.org/article/3af8442529d84d9b9fd3237d94369e9d
Autor:
David W. Hawman, Kimberly Meade-White, Chad Clancy, Jacob Archer, Troy Hinkley, Shanna S. Leventhal, Deepashri Rao, Allie Stamper, Matthew Lewis, Rebecca Rosenke, Kyle Krieger, Samantha Randall, Amit P. Khandhar, Linhue Hao, Tien-Ying Hsiang, Alexander L. Greninger, Michael Gale, Jr, Peter Berglund, Deborah Heydenburg Fuller, Kyle Rosenke, Heinz Feldmann, Jesse H. Erasmus
Publikováno v:
EBioMedicine, Vol 83, Iss , Pp 104196- (2022)
Summary: Background: In late 2021, the SARS-CoV-2 Omicron (B.1.1.529) variant of concern (VoC) was reported with many mutations in the viral spike protein that were predicted to enhance transmissibility and allow viral escape of neutralizing antibodi
Externí odkaz:
https://doaj.org/article/ab324282f355407caf9cfe9a89fda64c
Autor:
Sidy Bane, Kyle Rosenke, Ousmane Maiga, Friederike Feldmann, Kimberly Meade-White, Julie Callison, David Safronetz, Nafomon Sogoba, Heinz Feldmann
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 6, Pp 1681-1684 (2021)
Mali had 2 reported introductions of Ebola virus (EBOV) during the 2013–2016 West Africa epidemic. Previously, no evidence for EBOV circulation was reported in Mali. We performed an EBOV serosurvey study in southern Mali. We found low seroprevalenc
Externí odkaz:
https://doaj.org/article/4698ea7eb2e341e3ae9540af0e8c052b
Autor:
Kyle Rosenke, Atsushi Okumura, Matthew C. Lewis, Friederike Feldmann, Kimberly Meade-White, W. Forrest Bohler, Amanda Griffin, Rebecca Rosenke, Carl Shaia, Michael A. Jarvis, Heinz Feldmann
Publikováno v:
JCI Insight, Vol 7, Iss 13 (2022)
The recent emergence of the SARS-CoV-2 Omicron variant of concern (VOC), which contains a heavily mutated spike protein capable of escaping preexisting immunity, identifies a continued need for interventional measures. Molnupiravir (MK-4482), an oral
Externí odkaz:
https://doaj.org/article/f79bebb8c067469d87b3b0e305f5ae71
Autor:
Kyle Rosenke, Frederick Hansen, Benjamin Schwarz, Friederike Feldmann, Elaine Haddock, Rebecca Rosenke, Kent Barbian, Kimberly Meade-White, Atsushi Okumura, Shanna Leventhal, David W. Hawman, Emily Ricotta, Catharine M. Bosio, Craig Martens, Greg Saturday, Heinz Feldmann, Michael A. Jarvis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
While vaccines protecting against SARS-CoV-2 infection are approved, currently, there are no drugs suitable for high-risk exposure use against SARS-CoV-2. Here, Rosenke et al. provide evidence that orally delivered MK-4482, a nucleoside analog, inhib
Externí odkaz:
https://doaj.org/article/9a78a63a312847aa863ae1016f4d581a
Autor:
Kyle Rosenke, Friederike Feldmann, Atsushi Okumura, Frederick Hansen, Tsing-Lee Tang-Huau, Kimberly Meade-White, Benjamin Kaza, Julie Callison, Matthew C. Lewis, Brian J. Smith, Patrick W. Hanley, Jamie Lovaglio, Michael A. Jarvis, Carl Shaia, Heinz Feldmann
Publikováno v:
Emerging Microbes and Infections, Vol 10, Iss 1, Pp 2173-2182 (2021)
The continuing emergence of SARS-CoV-2 variants calls for regular assessment to identify differences in viral replication, shedding and associated disease. In this study, we compared African green monkeys infected intranasally with either the UK B.1.
Externí odkaz:
https://doaj.org/article/8c4cfecdfb7f4ce6b472dcefa93fa95e