Výsledky vyhledávání - "Kyle, Pressley"

Supplementary figure legend from Everolimus Inhibits the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer Via Downregulation of MMP9 Expression

Autor: Lu-Zhe Sun, Ismail Jatoi, Virginia Kaklamani, Andrew J. Brenner, Alia Nazarullah, Larry E. Broome, Guixi Zheng, Bingzhi Wang, Hakim Bouamar, Kyle Pressley, Xiao-Fei Ding, Guang Chen

Supplementary figure legend

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e9c512c18cb2a50206ff2e4cbf8640
https://doi.org/10.1158/1078-0432.22479281

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Data from Everolimus Inhibits the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer Via Downregulation of MMP9 Expression

Autor: Lu-Zhe Sun, Ismail Jatoi, Virginia Kaklamani, Andrew J. Brenner, Alia Nazarullah, Larry E. Broome, Guixi Zheng, Bingzhi Wang, Hakim Bouamar, Kyle Pressley, Xiao-Fei Ding, Guang Chen

Purpose:We evaluated the role of everolimus in the prevention of ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) progression.Experimental Design:The effects of everolimus on breast cancer cell invasion, DCIS formation, and DCIS pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea154f99cde8044fcdbfbaa184c24f2
https://doi.org/10.1158/1078-0432.c.6530177.v1

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Figure S1 from Everolimus Inhibits the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer Via Downregulation of MMP9 Expression

Autor: Lu-Zhe Sun, Ismail Jatoi, Virginia Kaklamani, Andrew J. Brenner, Alia Nazarullah, Larry E. Broome, Guixi Zheng, Bingzhi Wang, Hakim Bouamar, Kyle Pressley, Xiao-Fei Ding, Guang Chen

mTOR inhibition decreases MMP9 expression. A, Everolimus treatment for 24 hours did not reduced MMP2 protein levels in SUM225 cells. B, C and D figures were the MMP-9 IHC quantification data measuring average optical density using ImageJ d 1.47 softw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07378b542143c61f00d9ed1e7f777e07
https://doi.org/10.1158/1078-0432.22479284

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Everolimus Inhibits the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer Via Downregulation of MMP9 Expression

Autor: Virginia G. Kaklamani, Alia Nazarullah, Hakim Bouamar, Andrew Brenner, Kyle Pressley, Lu-Zhe Sun, Xiao Fei Ding, Guang Chen, Bingzhi Wang, Guixi Zheng, Ismail Jatoi, Larry E. Broome

Publikováno v: Clinical Cancer Research. 26:1486-1496

Purpose: We evaluated the role of everolimus in the prevention of ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) progression. Experimental Design: The effects of everolimus on breast cancer cell invasion, DCIS formation, and DCIS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::978b73db640bc83b569ed57567a3ea7c
https://doi.org/10.1158/1078-0432.ccr-19-2478

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Everolimus Inhibits the Progression of Ductal Carcinoma

Autor: Guang, Chen, Xiao-Fei, Ding, Kyle, Pressley, Hakim, Bouamar, Bingzhi, Wang, Guixi, Zheng, Larry E, Broome, Alia, Nazarullah, Andrew J, Brenner, Virginia, Kaklamani, Ismail, Jatoi, Lu-Zhe, Sun

Publikováno v: Clin Cancer Res

PURPOSE: We evaluated the role of everolimus in the prevention of ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) progression. EXPERIMENTAL DESIGN: The effects of everolimus on breast cancer cell invasion, DCIS formation, and DCIS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2567e76237b3edd23b6652b32892103b
https://pubmed.ncbi.nlm.nih.gov/31871301

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Everolimus induces G(1) cell cycle arrest through autophagy-mediated protein degradation of cyclin D1 in breast cancer cells

Autor: Lu-Zhe Sun, Kyle Pressley, Hakim Bouamar, Guang Chen, Xiaofei Ding

Publikováno v: Am J Physiol Cell Physiol

Everolimus inhibits mammalian target of rapamycin complex 1 (mTORC1) and is known to cause induction of autophagy and G1 cell cycle arrest. However, it remains unknown whether everolimus-induced autophagy plays a critical role in its regulation of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b275dac6e9966a1288d0241ae64a52c
https://europepmc.org/articles/PMC6732424/

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Abstract P6-04-01: Rapalog everolimus induces G1 cell cycle arrest through autophagy-mediated protein degradation of cyclin D1 in breast cancer cells

Autor: Hakim Bouamar, Kyle Pressley, Guang Chen, L-Z Sun, X-F Ding, Juechen Yang

Publikováno v: Cancer Research. 78:P6-04

Rapamycin analogs (rapalogs) inhibit mammalian target of rapamycin (mTOR) and are known to cause induction of autophagy and G1 cell cycle arrest. However, it remains unknown whether rapalog-induced autophagy plays a critical role in its regulation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eef102149633026966ebf6f304707949
https://doi.org/10.1158/1538-7445.sabcs17-p6-04-01

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Abstract 914: Age-associated neoplastic transformation of mammary stem cells

Autor: Hakim Bouamar, Kyle Pressley, Xiang Gu, Lu-Zhe Sun

Publikováno v: Cancer Research. 77:914-914

Incidence rate of breast cancer increases significantly with age. However, the mechanism of age-associated mammary tumorigenesis is unknown. Although mammary stem/progenitor cells have been proposed as the cells of origin for breast cancer, the mecha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c69385ee956192db65c0ea2b845d52e
https://doi.org/10.1158/1538-7445.am2017-914

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