Zobrazeno 1 - 10
of 357 706
pro vyhledávání: '"Kyle"'
Autor:
Thomas-Shadi Voges, Eun Bi Lim, Abigail MacKenzie, Kyle Mudler, Rebecca DeSouza, Nmesoma E. Onyejekwe, Stephen D. Johnston
Publikováno v:
BMC Research Notes, Vol 17, Iss 1, Pp 1-4 (2024)
Abstract Objectives Cox10 is an enzyme required for the activity of cytochrome c oxidase. Humans who lack at least one functional copy of Cox10 have a form of Leigh Syndrome, a genetic disease that is usually fatal in infancy. As more human genomes a
Externí odkaz:
https://doaj.org/article/5977836f7c7d43b5be1c5613077aa03b
Publikováno v:
BMC Plant Biology, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background In recent years, covalent modifications on RNA nucleotides have emerged as pivotal moieties influencing the structure, function, and regulatory processes of RNA Polymerase II transcripts such as mRNAs and lncRNAs. However, our und
Externí odkaz:
https://doaj.org/article/dbe0a14ac2dc4cdeb8a461c8cdd39926
Autor:
Christos S. Karamitros, Kyle Murray, Yoichi Kumada, Kenneth A. Johnson, Sheena D’Arcy, George Georgiou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Laboratory evolution studies have demonstrated that parallel evolutionary trajectories can lead to genetically distinct enzymes with high activity towards a non-preferred substrate. However, it is unknown whether such enzymes have convergent
Externí odkaz:
https://doaj.org/article/d47db4239cdf447f9b81a35c63bae465
Autor:
Gregory Holste, Mingquan Lin, Ruiwen Zhou, Fei Wang, Lei Liu, Qi Yan, Sarah H. Van Tassel, Kyle Kovacs, Emily Y. Chew, Zhiyong Lu, Zhangyang Wang, Yifan Peng
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Deep learning has enabled breakthroughs in automated diagnosis from medical imaging, with many successful applications in ophthalmology. However, standard medical image classification approaches only assess disease presence at the time of ac
Externí odkaz:
https://doaj.org/article/d5bb7ebb0d8746ec9edb8eafe05c20f8
Publikováno v:
Cell Death and Disease, Vol 15, Iss 8, Pp 1-13 (2024)
Abstract Smac mimetic compounds (SMCs) are small molecule drugs that sensitize cancer cells to TNF-α-induced cell death and have multiple immunostimulatory effects through alterations in NF-κB signaling. The combination of SMCs with immunotherapies
Externí odkaz:
https://doaj.org/article/e7dfa93325ff4ad39a2ad7f101b6277c
Publikováno v:
Journal of Eating Disorders, Vol 12, Iss 1, Pp 1-14 (2024)
Abstract Background Co-production is the collaboration between researchers and the lived experience community in designing, conducting and sharing research. The importance of co-production is increasingly advocated in both the autism and eating disor
Externí odkaz:
https://doaj.org/article/6f4650831735491e8f89b4eed9e4e544
Autor:
Silvia Liu, Caroline Obert, Yan-Ping Yu, Junhua Zhao, Bao-Guo Ren, Jia-Jun Liu, Kelly Wiseman, Benjamin J. Krajacich, Wenjia Wang, Kyle Metcalfe, Mat Smith, Tuval Ben-Yehezkel, Jian-Hua Luo
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background DNA sequencing is a critical tool in modern biology. Over the last two decades, it has been revolutionized by the advent of massively parallel sequencing, leading to significant advances in the genome and transcriptome sequencing
Externí odkaz:
https://doaj.org/article/0e1df677987f40f58e555f43618bcc7c
Autor:
Kyle C. Molina, Brandon J. Webb, Victoria Kennerley, Laurel E. Beaty, Tellen D. Bennett, Nichole E. Carlson, David A. Mayer, Jennifer L. Peers, Seth Russell, Matthew K. Wynia, Neil R. Aggarwal, Adit A. Ginde
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background A trial performed among unvaccinated, high-risk outpatients with COVID-19 during the delta period showed remdesivir reduced hospitalization. We used our real-world data platform to determine the effectiveness of remdesivir on redu
Externí odkaz:
https://doaj.org/article/3e8ea79849a7468ea7505d78a68e5792
Autor:
Ian Eisenman, Kyle C. Armour
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Paleoclimate records have been used to estimate the modern equilibrium climate sensitivity. However, this requires understanding how the feedbacks governing the climate response vary with the climate itself. Here we warm and cool a state-of-
Externí odkaz:
https://doaj.org/article/7d6689a0dc3149de8b96ddae15d6229f
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background In the United States in 2017, there were an estimated 903,745 hospitalizations involving mechanical ventilation (MV). Complications from ventilation can result in longer hospital stays, increased risk of disability, and increased
Externí odkaz:
https://doaj.org/article/f571e2e350d942a395d938f239e270d4