Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Kyla Shea"'
Publikováno v:
Current Developments in Nutrition, Vol 8, Iss 8, Pp 104418- (2024)
The hormonally active form of vitamin D, 1,25-Dihydroxyvitamin D3 [1,25(OH)2D3], has been associated with neuroprotective effects in the brain, but has been difficult to measure in human brain tissue because of its low concentration. The aim of this
Externí odkaz:
https://doaj.org/article/df92141bf8ee4af9884c4f32bb670414
Autor:
Sarah L. Booth, M. Kyla Shea, Kathryn Barger, Sue E. Leurgans, Bryan D. James, Thomas M. Holland, Puja Agarwal, Xueyan Fu, Jifan Wang, Gregory Matuszek, Julie A. Schneider
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Higher vitamin K intakes have been associated with better cognitive function, suggestive of a vitamin K mechanistic effect or simply reflective of a healthy diet. To test the hypothesis that brain vitamin K is linked to cognitive decline and
Externí odkaz:
https://doaj.org/article/78cb081fa36f491da1325e8f7b1230c0
Autor:
M. Kyla Shea, Sarah L. Booth, Stephanie G. Harshman, Donald Smith, Cathy S. Carlson, Lindsey Harper, Alexandra R. Armstrong, Min Fang, M. Leonor Cancela, Márcio Simão, Richard F. Loeser
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 2, Iss 3, Pp 100078- (2020)
Summary: Objective: While a role for vitamin K in maintaining joint tissue homeostasis has been proposed based on the presence of vitamin K dependent proteins in cartilage and bone, it is not clear if low vitamin K intake is causally linked to joint
Externí odkaz:
https://doaj.org/article/d10933dfac2842a89f31ef84237a99cd
Autor:
Xia Jiang, Paul F. O’Reilly, Hugues Aschard, Yi-Hsiang Hsu, J. Brent Richards, Josée Dupuis, Erik Ingelsson, David Karasik, Stefan Pilz, Diane Berry, Bryan Kestenbaum, Jusheng Zheng, Jianan Luan, Eleni Sofianopoulou, Elizabeth A. Streeten, Demetrius Albanes, Pamela L. Lutsey, Lu Yao, Weihong Tang, Michael J. Econs, Henri Wallaschofski, Henry Völzke, Ang Zhou, Chris Power, Mark I. McCarthy, Erin D. Michos, Eric Boerwinkle, Stephanie J. Weinstein, Neal D. Freedman, Wen-Yi Huang, Natasja M. Van Schoor, Nathalie van der Velde, Lisette C. P. G. M. de Groot, Anke Enneman, L. Adrienne Cupples, Sarah L. Booth, Ramachandran S. Vasan, Ching-Ti Liu, Yanhua Zhou, Samuli Ripatti, Claes Ohlsson, Liesbeth Vandenput, Mattias Lorentzon, Johan G. Eriksson, M. Kyla Shea, Denise K. Houston, Stephen B. Kritchevsky, Yongmei Liu, Kurt K. Lohman, Luigi Ferrucci, Munro Peacock, Christian Gieger, Marian Beekman, Eline Slagboom, Joris Deelen, Diana van Heemst, Marcus E. Kleber, Winfried März, Ian H. de Boer, Alexis C. Wood, Jerome I. Rotter, Stephen S. Rich, Cassianne Robinson-Cohen, Martin den Heijer, Marjo-Riitta Jarvelin, Alana Cavadino, Peter K. Joshi, James F. Wilson, Caroline Hayward, Lars Lind, Karl Michaëlsson, Stella Trompet, M. Carola Zillikens, Andre G. Uitterlinden, Fernando Rivadeneira, Linda Broer, Lina Zgaga, Harry Campbell, Evropi Theodoratou, Susan M. Farrington, Maria Timofeeva, Malcolm G. Dunlop, Ana M. Valdes, Emmi Tikkanen, Terho Lehtimäki, Leo-Pekka Lyytikäinen, Mika Kähönen, Olli T. Raitakari, Vera Mikkilä, M. Arfan Ikram, Naveed Sattar, J. Wouter Jukema, Nicholas J. Wareham, Claudia Langenberg, Nita G. Forouhi, Thomas E. Gundersen, Kay-Tee Khaw, Adam S. Butterworth, John Danesh, Timothy Spector, Thomas J. Wang, Elina Hyppönen, Peter Kraft, Douglas P. Kiel
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Vitamin D deficiency is associated with multiple human pathologic conditions. In a genome-wide association study of 79,366 individuals, Jiang et al. replicate four and identify two new genetic loci for serum levels of 25-hydroxyvitamin D and find evi
Externí odkaz:
https://doaj.org/article/45ceebb3cb0e4473b2cfdeb800d4099c
Autor:
M Kyla Shea, Andres V Ardisson Korat, Paul F Jacques, Paola Sebastiani, Rebecca Cohen, Amy E LaVertu, Sarah L Booth
Publikováno v:
Adv Nutr
By 2060, the number of adults aged ≥65 y is expected to double, and the ≥85 y segment of the population is expected to triple in the United States. US federal nutrition guidance is based on the premise that healthy diets contribute to delaying th
Autor:
M Kyla, Shea, Kathryn, Barger, Bess, Dawson-Hughes, Sue E, Leurgans, Xueyan, Fu, Bryan D, James, Thomas M, Holland, Puja, Agarwal, Jifan, Wang, Gregory, Matuszek, Nicholas E, Heger, Julie A, Schneider, Sarah L, Booth
Publikováno v:
Alzheimer's & Dementia.
Vitamin D purportedly protects against cognitive decline and dementia based on observational data using circulating 25-hydroxyvitamin D (25(OH)D). Little is known about vitamin D in the human brain and the association with dementia or neuropathology.
Autor:
Jasmin M Strong, Xueyan Fu, Erik A. Taylor, Sophie D. Dornevil, Eve Donnelly, Sarah L. Booth, Manuela Vargas Rojas, Rodrigo C. Bicalho, Christopher J. Hernandez, Jacob C. Nixon, Laura S Vasquez-Bolanos, Jason D Guss, M. Kyla Shea, Denise A Alabi, Macy Castaneda, Marysol Luna
Publikováno v:
J Bone Miner Res
Modifications to the constituents of the gut microbiome influence bone density and tissue-level strength, but the specific microbial components that influence tissue-level strength in bone are not known. Here, we selectively modify constituents of th
Publikováno v:
European Journal of Clinical Nutrition. 76:335-339
Autor:
Rachel M Holden, Sarah L Booth, Deborah Zimmerman, Louise Moist, Patrick A Norman, Andrew G Day, Alex Menard, Xueyan Fu, M Kyla Shea, Corinne S Babiolakis, Robert Nolan, Mandy E Turner, Emilie Ward, Martin Kaufmann, Michael A Adams, Daren K Heyland
Publikováno v:
Nephrol Dial Transplant
Background Vitamin K activates matrix Gla protein (MGP), a key inhibitor of vascular calcification. There is a high prevalence of sub-clinical vitamin K deficiency in patients with end-stage kidney disease. Methods A parallel randomized placebo-contr
Autor:
Xueyan Fu, Bess Dawson-Hughes, William B. Patterson, Gregory G. Dolnikowski, Thomas Holland, M. Kyla Shea, Julie A. Schneider, Sarah L. Booth
Publikováno v:
J Nutr
BACKGROUND: Vitamins D and K, which are present in human brain, may have a role in neurodegenerative disease. OBJECTIVES: Given the interest in measuring nutrient concentrations in archived brain samples, it is important to evaluate whether freezer s