Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Kyla D Omilusik"'
Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
Elevation of intracellular calcium ion (Ca2+) levels is a vital event that regulates T lymphocyte homeostasis, activation, proliferation, differentiation, and apoptosis. The mechanisms that regulate intracellular Ca2+ signalling in lymphocytes involv
Externí odkaz:
https://doaj.org/article/4ac15bd757264a0fbb296cbcd1cb8755
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
Calcium (Ca2+) is a universal second messenger important for T lymphocyte homeostasis, activation, proliferation, differentiation and apoptosis. The events surrounding Ca2+ mobilization in lymphocytes are tightly regulated and involve the coordinatio
Externí odkaz:
https://doaj.org/article/ed3e6d4843e8485da005061a7e2baed7
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7210 (2009)
Cross-presentation is now recognized as a major mechanism for initiating CD8 T cell responses to virus and tumor antigens in vivo. It provides an elegant mechanism that allows relatively few Dendritic cells (DCs) to initiate primary immune responses
Externí odkaz:
https://doaj.org/article/f008991366384ea298d296688d6391cc
Autor:
Genc Basha, Gregory Lizée, Anna T Reinicke, Robyn P Seipp, Kyla D Omilusik, Wilfred A Jefferies
Publikováno v:
PLoS ONE, Vol 3, Iss 9, p e3247 (2008)
BACKGROUND: Cross-presentation by dendritic cells (DCs) is a crucial prerequisite for effective priming of cytotoxic T-cell responses against bacterial, viral and tumor antigens; however, this antigen presentation pathway remains poorly defined. METH
Externí odkaz:
https://doaj.org/article/5783abe10b6c4f6dbad0b0857d88d54e
Autor:
Quynh P. Nguyen, Kennidy K. Takehara, Tianda Z. Deng, Shannon O’Shea, Maximilian Heeg, Kyla D. Omilusik, J. Justin Milner, Sara Quon, Matthew E. Pipkin, Jinyong Choi, Shane Crotty, Ananda W. Goldrath
Publikováno v:
Science Immunology. 8
After resolution of infection, T cells differentiate into long-lived memory cells that recirculate through secondary lymphoid organs or establish residence in tissues. In contrast to CD8 + tissue-resident memory T cells (T RM ), the developmental ori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8942a3bd04073df75435c1a7b19599bd
https://doi.org/10.1126/sciimmunol.abq7486
https://doi.org/10.1126/sciimmunol.abq7486
Autor:
John T. Crowl, Maximilian Heeg, Amir Ferry, J. Justin Milner, Kyla D. Omilusik, Clara Toma, Zhaoren He, John T. Chang, Ananda W. Goldrath
Publikováno v:
Nat Immunol
Nature immunology, vol 23, iss 7
Nature immunology, vol 23, iss 7
Tissue-resident memory T cells (T(RM) cells) provide protective immunity, but the contributions of specific tissue environments to T(RM) cell differentiation and homeostasis are not well understood. In the present study, the diversity of gene express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071a46f29b7678c014a5975706c2a1fe
https://doi.org/10.1038/s41590-022-01229-8
https://doi.org/10.1038/s41590-022-01229-8
Autor:
Laura A, Shaw, Tianda Z, Deng, Kyla D, Omilusik, Kennidy K, Takehara, Quynh P, Nguyen, Ananda W, Goldrath
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(29)
Memory CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b836e2b3c6f2c28a4b0cb16f909b9f1
https://pubmed.ncbi.nlm.nih.gov/35858332
https://pubmed.ncbi.nlm.nih.gov/35858332
Autor:
John T, Crowl, Maximilian, Heeg, Amir, Ferry, J Justin, Milner, Kyla D, Omilusik, Clara, Toma, Zhaoren, He, John T, Chang, Ananda W, Goldrath
Publikováno v:
Nature immunology. 23(7)
Tissue-resident memory T cells (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28e3449b38b9fb51ff86d7543bac0599
https://pubmed.ncbi.nlm.nih.gov/36089486
https://pubmed.ncbi.nlm.nih.gov/36089486
Autor:
Kyla D. Omilusik, Ananda W. Goldrath
Publikováno v:
Curr Opin Immunol
Upon activation, naive T cells give rise to a heterogeneous cell population of effector and memory T cells that mediate antigen clearance and provide long-lived protection from rechallenge. Many of the transcriptional regulators that direct the diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4145995ba8bb9c597a02f32f88a8462b
https://doi.org/10.1016/j.coi.2019.04.009
https://doi.org/10.1016/j.coi.2019.04.009
Autor:
Kyla D. Omilusik, Charlotte L. Scott
Publikováno v:
TRENDS IN IMMUNOLOGY
ZEB1 and ZEB2 are zinc-finger E homeobox-binding transcription factors best known for their role in driving epithelial to mesenchymal transition. However, in recent years our understanding of these two transcription factors has broadened, and it is n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763829f8a2e50e9fe97a5f18cc7a3882
https://doi.org/10.1016/j.it.2019.03.001
https://doi.org/10.1016/j.it.2019.03.001