Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kyla Buettner"'
Autor:
Fang Yu, Kelsey Klute, Kamiya Mehla, Ravi Thakur, Gavin Graves, Junichi Sadoshima, Rebecca E. Oberley-Deegan, Michael A. Hollingsworth, Divya Murthy, Camila G. Pacheco, Scott E. Mulder, Nina V. Chaika, Kuldeep S. Attri, Kyla Buettner, Melissa Teoh-Fitzgerald, Pankaj K. Singh, Jaime Abrego, Ibha Rai, Paul M. Grandgenett, Aneesha Dasgupta, Bradley N. Reames, Surendra K. Shukla, David A. Tuveson, Enza Vernucci, Nicholas J Mullen, Ryan J. King, Dezhen Wang, Michael Punsoni, Matthew C. Zimmerman, Dannielle D. Engle
Publikováno v:
The Journal of experimental medicine, vol 217, iss 7
The Journal of Experimental Medicine
The Journal of Experimental Medicine
This study demonstrates a novel signaling pathway regulating pancreatic cancer cachexia. These results establish that the Sirt1–Nox4 signaling axis plays an essential role in the manifestation of pancreatic cancer cachexia, and inhibition of this a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95eacb1b84092379889e72b0d37e57c
https://escholarship.org/uc/item/1xf460n5
https://escholarship.org/uc/item/1xf460n5
Autor:
Surendra K. Shukla, Enza Vernucci, Alysha L. Illies, Venugopal Gunda, Aneesha Dasgupta, Jaime Abrego, Benjamin J. Swanson, Pankaj K. Singh, Kyla Buettner, Fang Yu, Vikrant Rai, Nina V. Chaika, Audrey J. Lazenby
Publikováno v:
Cancers
Volume 12
Issue 1
Volume 12
Issue 1
Pancreatic cancer is the third leading cause of cancer-related deaths in the USA. Pancreatic tumors are characterized by enhanced glycolytic metabolism promoted by a hypoxic tumor microenvironment and a resultant acidic milieu. The metabolic reprogra
Autor:
Aneesha Dasgupta, Enza Vernucci, Surendra K. Shukla, Scott E. Mulder, Ryan J. King, Jaime Abrego, Nina V. Chaika, Kyla Buettner, Pankaj K. Singh
Publikováno v:
Cancer Research. 78:5483-5483
Cancer-associated cachexia is a complex metabolic syndrome which leads to excessive loss of skeletal muscle and adipose deposits. Up to 80% of pancreatic cancer patients suffer from cachexia and nearly one third die due to complexities related to the