Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Kyeonghee Shim"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 4, Pp 3175-3192 (2024)
Nur77 belongs to the NR4A subfamily of orphan nuclear hormone receptors. It has been shown to play important roles in metabolism, cancer progression, cellular differentiation, and the regulation of immune process. However, there has yet to be researc
Externí odkaz:
https://doaj.org/article/aaff946db6304382913e8fdd2e493e1c
Autor:
Minjeong Yeon, Hankyu Lee, Jeongseon Yeo, Myeong Seon Jeong, Hyun Suk Jung, Hyerim Lee, Kyeonghee Shim, Hyein Jo, Doyong Jeon, Jaemoon Koh, Dooil Jeoung
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract CAGE, a cancer/testis antigen, was originally isolated from the sera of patients with gastric cancers. Previously, we have shown the role of CAGE in resistance to chemotherapy and target therapy. The aim of this study was to investigate the
Externí odkaz:
https://doaj.org/article/b1187bc5d1fb4061a0bc6d1954eddb61
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 2048-2057 (2023)
Histone deacetylases (HDACs) deacetylate histones H3 and H4. An imbalance between histone acetylation and deacetylation can lead to various diseases. HDAC2 is present in the nucleus. It plays a critical role in modifying chromatin structures and regu
Externí odkaz:
https://doaj.org/article/551820f2c00546379744679faa0ec60f
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14679 (2023)
In the last few decades, RNA-based drugs have emerged as a promising candidate in the treatment of various diseases. The introduction of messenger RNA (mRNA) as a vaccine or therapeutic agent enables the production of almost any functional protein/pe
Externí odkaz:
https://doaj.org/article/722300b4343c46b4acc0e4f5d777f0ef
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1465 (2023)
Exosomes are a subset of extracellular vesicles produced by all cells, and they are present in various body fluids. Exosomes play crucial roles in tumor initiation/progression, immune suppression, immune surveillance, metabolic reprogramming, angioge
Externí odkaz:
https://doaj.org/article/f9c08676bf0f48489475e1ef87f39d2f
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3436 (2023)
Senescence occurs in response to various stimuli. Senescence has attracted attention because of its potential use in anticancer therapy as it plays a tumor-suppressive role. It also promotes tumorigeneses and therapeutic resistance. Since senescence
Externí odkaz:
https://doaj.org/article/f10d3ddc0ec141cbac73bc63fe5d6acd
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 4225 (2023)
RNA methylations play critical roles in RNA processes, including RNA splicing, nuclear export, nonsense-mediated RNA decay, and translation. Regulators of RNA methylations have been shown to be differentially expressed between tumor tissues/cancer ce
Externí odkaz:
https://doaj.org/article/5ac4feee5b1c451897b38a67ad7b29bd
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 13892 (2022)
Sphingolipid molecules have recently attracted attention as signaling molecules in allergic inflammation diseases. Sphingosine-1-phosphate (S1P) is synthesized by two isoforms of sphingosine kinases (SPHK 1 and SPHK2) and is known to be involved in v
Externí odkaz:
https://doaj.org/article/52744bfca9294f01affbd044c5e48720
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9592 (2022)
Histone deacetylases (HDACs) regulate gene expression through the epigenetic modification of chromatin structure. HDAC6, unlike many other HDACs, is present in the cytoplasm. Its deacetylates non-histone proteins and plays diverse roles in cancer cel
Externí odkaz:
https://doaj.org/article/3088f086ace145bf9f61c693f941a451
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 5881 (2022)
MicroRNAs (miRNAs) are small non-coding RNAs (18–24 nucleotides) that play significant roles in cell proliferation, development, invasion, cancer development, cancer progression, and anti-cancer drug resistance. miRNAs target multiple genes and pla
Externí odkaz:
https://doaj.org/article/fe808726e3284c948c590330cc58f825