Zobrazeno 1 - 10
of 58
pro vyhledávání: '"KyeongEun Lee"'
Autor:
Kyeongeun Lee, Jeongwon Han
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract In this study, we conducted a numerical analysis on catheter sizes using computational fluid dynamics to assess urinary flow rates during intermittent catheterization (IC). The results revealed that the fluid (urine) movement within a cathet
Externí odkaz:
https://doaj.org/article/b05ab7de0e9a49868693d841de52e79b
Autor:
Charlotte Luchsinger, KyeongEun Lee, Gonzalo A. Mardones, Vineet N. KewalRamani, Felipe Diaz-Griffero
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract The early events of HIV-1 infection involve the transport of the viral core into the nucleus. This event triggers the translocation of CPSF6 from paraspeckles into nuclear speckles forming puncta-like structures. Our investigations revealed
Externí odkaz:
https://doaj.org/article/b4643a6316854a37b63672e8d9b91525
Autor:
Guangai Xue, Hyun Jae Yu, Cindy Buffone, Szu-Wei Huang, KyeongEun Lee, Shih Lin Goh, Anna T. Gres, Mehmet Hakan Guney, Stefan G. Sarafianos, Jeremy Luban, Felipe Diaz-Griffero, Vineet N. KewalRamani
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The movement of viruses and other large macromolecular cargo through nuclear pore complexes (NPCs) is poorly understood. The human immunodeficiency virus type 1 (HIV-1) provides an attractive model to interrogate this process. HIV-1 capsid (
Externí odkaz:
https://doaj.org/article/b5c0d59bc5e54f7c8f940895d1b03f4a
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
IntroductionThis study aimed to investigate the association between social determinants of health and perception of COVID-19 social distancing/mental health/quality of life during COVID-19 social distancing in Korean undergraduate students using onli
Externí odkaz:
https://doaj.org/article/49f144babed9436c850b52e1c092b48d
Autor:
Anastasia Selyutina, Pan Hu, Sorin Miller, Lacy M. Simons, Hyun Jae Yu, Judd F. Hultquist, KyeongEun Lee, Vineet N. KewalRamani, Felipe Diaz-Griffero
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103593- (2022)
Summary: The HIV-1 capsid is the target for the antiviral drugs GS-CA1 and Lenacapavir (GS-6207). We investigated the mechanism by which GS-CA1 and GS-6207 inhibit HIV-1 infection. HIV-1 inhibition by GS-CA1 did not require CPSF6 in CD4+ T cells. Con
Externí odkaz:
https://doaj.org/article/4ae7188a6055437183234d325cc37399
Autor:
Wen Li, Parmit K. Singh, Gregory A. Sowd, Gregory J. Bedwell, Sooin Jang, Vasudevan Achuthan, Amarachi V. Oleru, Doris Wong, Hind J. Fadel, KyeongEun Lee, Vineet N. KewalRamani, Eric M. Poeschla, Alon Herschhorn, Alan N. Engelman
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Lentiviral DNA integration favors transcriptionally active chromatin. We previously showed that the interaction of human immunodeficiency virus type 1 (HIV-1) capsid with cleavage and polyadenylation specificity factor 6 (CPSF6) localizes vi
Externí odkaz:
https://doaj.org/article/7f4eaeb2c24147479988497d78e83da7
Autor:
Amanda J Price, Adam J Fletcher, Torsten Schaller, Tom Elliott, KyeongEun Lee, Vineet N KewalRamani, Jason W Chin, Greg J Towers, Leo C James
Publikováno v:
PLoS Pathogens, Vol 8, Iss 8, p e1002896 (2012)
The HIV-1 genome enters cells inside a shell comprised of capsid (CA) protein. Variation in CA sequence alters HIV-1 infectivity and escape from host restriction factors. However, apart from the Cyclophilin A-binding loop, CA has no known interfaces
Externí odkaz:
https://doaj.org/article/7ebe256ec2ca4132a1a8a19a34467a08
Autor:
Torsten Schaller, Karen E Ocwieja, Jane Rasaiyaah, Amanda J Price, Troy L Brady, Shoshannah L Roth, Stéphane Hué, Adam J Fletcher, KyeongEun Lee, Vineet N KewalRamani, Mahdad Noursadeghi, Richard G Jenner, Leo C James, Frederic D Bushman, Greg J Towers
Publikováno v:
PLoS Pathogens, Vol 7, Iss 12, p e1002439 (2011)
Lentiviruses such as HIV-1 traverse nuclear pore complexes (NPC) and infect terminally differentiated non-dividing cells, but how they do this is unclear. The cytoplasmic NPC protein Nup358/RanBP2 was identified as an HIV-1 co-factor in previous stud
Externí odkaz:
https://doaj.org/article/a5b5dc81b6be4ecc85627141155f796e
Autor:
Vyacheslav Furtak, Alok Mulky, Stephen A Rawlings, Lina Kozhaya, KyeongEun Lee, Vineet N Kewalramani, Derya Unutmaz
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9081 (2010)
Exogenous retroviruses are obligate cellular parasites that co-opt a number of host proteins and functions to enable their replication and spread. Several host factors that restrict HIV and other retroviral infections have also recently been describe
Externí odkaz:
https://doaj.org/article/eb4709a39b46474ab861786997d0e430
Publikováno v:
ACS Applied Materials & Interfaces. 14:38153-38161
Protective equipment for detecting bacterial contamination has been in high demand with increasing interest in public health and hygiene. Herein, a fiber-based visually indicating bacteria sensor (VIBS) embedded with iodonitrotetrazolium chloride is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485f3de2f28d3daf77e764521a88c7c1
https://doi.org/10.1021/acsami.2c08613
https://doi.org/10.1021/acsami.2c08613