Zobrazeno 1 - 10 of 55 pro vyhledávání: '"Kyeong-Won Lee"'
1
Akademický článek
Structural and biochemical investigation into stable FGF2 mutants with novel mutation sites and hydrophobic replacements for surface-exposed cysteines.
Autor: Young Jun An, Ye-Eun Jung, Kyeong Won Lee, Prashant Kaushal, In Young Ko, Seung Min Shin, Sangho Ji, Wookyung Yu, Cheolju Lee, Won-Kyu Lee, Kiweon Cha, Jung-Hyun Lee, Sun-Shin Cha, Hyung-Soon Yim
Publikováno v: PLoS ONE, Vol 19, Iss 9, p e0307499 (2024)
Fibroblast growth factor 2 (FGF2) is an attractive biomaterial for pharmaceuticals and functional cosmetics. To improve the thermo-stability of FGF2, we designed two mutants harboring four-point mutations: FGF2-M1 (D28E/C78L/C96I/S137P) and FGF2-M2 (
Externí odkaz: https://doaj.org/article/40e83970943d41ca992fa7cd62a2cfcc
Zobrazit plný text záznamu
2
Akademický článek
Heating-mediated purification of active FGF21 and structure-based design of its variant with enhanced potency
Autor: Ye-Eun Jung, Kyeong Won Lee, Jae Hyun Cho, Da-Woon Bae, Bo-Gyeong Jeong, Yeon-Ju Jung, Soo-Bong Park, Young Jun An, Kyungchan Kim, Ga Seul Lee, Lin-Woo Kang, Jeong Hee Moon, Jung-Hyun Lee, Eun-Kyoung Kim, Hyung-Soon Yim, Sun-Shin Cha
Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Fibroblast growth factor 21 (FGF21) has pharmaceutical potential against obesity-related metabolic disorders, including non-alcoholic fatty liver disease. Since thermal stability is a desirable factor for therapeutic proteins, we investigate
Externí odkaz: https://doaj.org/article/cb322d3b33534efbb5addf9017d50905
Zobrazit plný text záznamu
3
Akademický článek
N-benzyl-N-methyldecan-1-amine and its derivative mitigate 2,4- dinitrobenzenesulfonic acid-induced colitis and collagen-induced rheumatoid arthritis
Autor: Ji Eun Kim, Changyu Kang, Phatcharaporn Budluang, Natpaphan Yawut, Il-Rae Cho, Yun Ju Choi, Jaejeong Kim, Sanghyun Ju, Beomgu Lee, Dong Hyun Sohn, Hyung-Soon Yim, Kyeong Won Lee, Jinsol Han, Youngmi Jung, Ho Young Kang, Jin Kyoon Park, Yunjin Jung, Dae Youn Hwang, Young-Hwa Chung
Publikováno v: Frontiers in Pharmacology, Vol 14 (2023)
As our previous study revealed that N-benzyl-N-methyldecan-1-amine (BMDA), a new molecule originated from Allium sativum, exhibits anti-neoplastic activities, we herein explored other functions of the compound and its derivative [decyl-(4-methoxy-ben
Externí odkaz: https://doaj.org/article/35bcd7a36ac2466ea03488283a585c87
Zobrazit plný text záznamu
4
Akademický článek
FGF11 influences 3T3‐L1 preadipocyte differentiation by modulating the expression of PPARγ regulators
Autor: Kyeong Won Lee, Jae‐Yeon Jeong, Young Jun An, Jung‐Hyun Lee, Hyung‐Soon Yim
Publikováno v: FEBS Open Bio, Vol 9, Iss 4, Pp 769-780 (2019)
Fibroblast growth factor 11 (FGF11) is a member of the intracellular fibroblast growth factor superfamily. Here, we identified FGF11 as a novel mediator of adipogenesis. During 3T3‐L1 adipocyte differentiation, the expression of FGF11 decreased at
Externí odkaz: https://doaj.org/article/2614ba34f1f74e318566a3ca54d5d7a5
Zobrazit plný text záznamu
6
Types of co-occurring patterns of mental health among the disaster victims in South Korea
Autor: Kyeong-Won Lee, Hyun Lee
Publikováno v: Development and Psychopathology. :1-8
This study examined co-occurring patterns of mental health among disaster victims using latent profile analysis and assessed the difference between sociodemographic factors and protective factors that affect group classification. The data of 2300 dis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b3ebe45c8b6b3f3118f8e395a71ccbc7
https://doi.org/10.1017/s0954579422001444
Zobrazit plný text záznamu
7
Akademický článek
iMGEins: detecting novel mobile genetic elements inserted in individual genomes
Autor: Junwoo Bae, Kyeong Won Lee, Mohammad Nazrul Islam, Hyung-Soon Yim, Heejin Park, Mina Rho
Publikováno v: BMC Genomics, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Recent advances in sequencing technology have allowed us to investigate personal genomes to find structural variations, which have been studied extensively to identify their association with the physiology of diseases such as canc
Externí odkaz: https://doaj.org/article/2e4aad485f044ff39f078b3b0bffaf6c
Zobrazit plný text záznamu
9
Akademický článek
Optimizing T4 DNA polymerase conditions enhances the efficiency of one-step sequence- and ligation-independent cloning
Autor: Mohammad Nazrul Islam, Kyeong Won Lee, Hyung-Soon Yim, Seong Hyuk Lee, Hae Chang Jung, Jung-Hyun Lee, Jae-Yeon Jeong
Publikováno v: BioTechniques, Vol 63, Iss 3, Pp 125-130 (2017)
Previously, we developed a one-step sequence- and ligation-independent cloning (SLIC) method that is simple, fast, and cost-effective. However, although one-step SLIC generally works well, its cloning efficiency is occasionally poor, potentially due
Externí odkaz: https://doaj.org/article/89f2f455697d4d41b6f270c1b1741fa4
Zobrazit plný text záznamu
10
The Analyses of Cetacean Virus-Responsive Genes Reveal Evolutionary Marks in Mucosal Immunity-Associated Genes
Autor: Oksung Chung, Ye-Eun Jung, Kyeong Won Lee, Young Jun An, Jungeun Kim, Yoo-Rim Roh, Jong Bhak, Kiejung Park, Jessica A. Weber, Jaehun Cheong, Sun-Shin Cha, Jung-Hyun Lee, Hyung-Soon Yim
Publikováno v: Biochemical Genetics. 60:2299-2312
Viruses are the most common and abundant organisms in the marine environment. To better understand how cetaceans have adapted to this virus-rich environment, we compared cetacean virus-responsive genes to those from terrestrial mammals. We identified
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d48c8600526478651a525d1baaad5d4c
https://doi.org/10.1007/s10528-022-10221-8
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje