Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Kyeong-Man Kim"'
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-23 (2024)
Abstract Transactivation of epidermal growth factor receptors (EGFR) provides intricate control over multiple regulatory cellular processes that merge the diversity of G protein-coupled receptors (GPCRs) with the robust signaling capacities of recept
Externí odkaz:
https://doaj.org/article/c809f781c35341f786a27114164239b3
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background Desensitization of G protein–coupled receptors (GPCRs) refers to a rapid attenuation of responsiveness that occurs with repeated or continuous exposure to agonists. GRK-mediated phosphorylation and subsequent binding with arrest
Externí odkaz:
https://doaj.org/article/821709d2f9954b0ab3725ffa08df6c5d
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
The mouse hippocampal neuronal cell line HT22 is frequently used as an in vitro model to investigate the role of hippocampal cholinergic neurons in cognitive functions. HT22 cells are derived from hippocampal neuronal HT4 cells. However, whether thes
Externí odkaz:
https://doaj.org/article/4c24426573094b1a98e9fe8d2f6c54bc
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68351 (2013)
Beta-arrestins (β-arrestin1 and β-arrestin2) are known as cytosolic proteins that mediate desensitization and internalization of activated G protein-coupled receptors. In addition to these functions, β-arrestins have been found to work as adaptor
Externí odkaz:
https://doaj.org/article/5940f0f370e64881b0d3dd21a3ac20f1
Publikováno v:
Biochemical and Biophysical Research Communications. 628:40-48
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6ddf2e8260bd97deaa3edfb57b97cf9
https://doi.org/10.1016/j.bbrc.2022.08.056
https://doi.org/10.1016/j.bbrc.2022.08.056
Publikováno v:
Biomolecules & Therapeutics. 31:176-182
Among 14 subtypes of serotonin receptors (5-HTRs), 5-HT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::606cfb49b597af4fa508b6fb9700d5ca
https://doi.org/10.4062/biomolther.2022.096
https://doi.org/10.4062/biomolther.2022.096
Autor:
Dooti, Kundu, Anlin, Zhu, Eunae, Kim, Suresh, Paudel, Choon-Gon, Jang, Yong Sup, Lee, Kyeong-Man, Kim
Publikováno v:
Biomolecules & Therapeutics. 31:108-115
Numerous psychotropic and addictive substances possess structural features similar to those of β-phenethylamine (β-PEA). In this study, we selected 29 β-PEA derivatives and determined their structure-activity relationship (SAR) to their ability to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73058e0afd893a8c1b596888b0f36325
https://doi.org/10.4062/biomolther.2022.047
https://doi.org/10.4062/biomolther.2022.047
Publikováno v:
British Journal of Pharmacology. 178:3498-3516
Background and purpose α4β2 nicotinic acetylcholine receptor (nAChR), a subtype of the ligand-gated ion channel, is abundantly expressed in the brain and implicated in several neurological disorders. The endocytosis of nAChR plays important roles i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d2653e26251673ff71d13db509b3f1d
https://doi.org/10.1111/bph.15495
https://doi.org/10.1111/bph.15495
Autor:
Srijan Acharya, Seung Hoon Cheon, Anlin Zhu, Kyeong-Man Kim, Eunae Kim, Suresh Paudel, Xiao Min
Publikováno v:
Biomolecules & Therapeutics
In this study, we determined the effect of 24 different synthetic 4-benzylpiperidine carboxamides on the reuptake of serotonin, norepinephrine, and dopamine (DA), and characterized their structure–activity relationship. The compounds with a two-car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d19790ba99e76979bf65daf91842be
http://europepmc.org/articles/PMC8255136
http://europepmc.org/articles/PMC8255136
Autor:
Kyeong-Man Kim
Publikováno v:
International Journal of Molecular Sciences. 24:6742
Dopamine receptors are classified into five subtypes, with D2R and D3R playing a crucial role in regulating mood, motivation, reward, and movement. Whereas D2R are distributed widely across the brain, including regions responsible for motor functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f25fecc20035e9739388eed0a5f3645c
https://doi.org/10.3390/ijms24076742
https://doi.org/10.3390/ijms24076742