Zobrazeno 1 - 10
of 255
pro vyhledávání: '"Kyeong Sook Choi"'
Autor:
Dong Min Lee, In Young Kim, Hong Jae Lee, Min Ji Seo, Mi-Young Cho, Hae In Lee, Gyesoon Yoon, Jae-Hoon Ji, Seok Soon Park, Seong-Yun Jeong, Eun Kyung Choi, Yong Hyeon Choi, Chae-Ok Yun, Mirae Yeo, Eunhee Kim, Kyeong Sook Choi
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Valosin-containing protein (VCP)/p97, an AAA+ ATPase critical for maintaining proteostasis, emerges as a promising target for cancer therapy. This study reveals that targeting VCP selectively eliminates breast cancer cells while sparing non-
Externí odkaz:
https://doaj.org/article/58476624d0874cd5bff24bb37660b19b
Autor:
Min Ji Seo, In Young Kim, Dong Min Lee, Yeon Jung Park, Mi-Young Cho, Hyo Joon Jin, Kyeong Sook Choi
Publikováno v:
Cell Death and Disease, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Auranofin (AF), a gold (I)-containing phosphine compound, is being investigated for oncological application as a repurposed drug. We show here that 4~5 µM AF induces paraptosis, a non-apoptotic cell death mode characterized by dilation of t
Externí odkaz:
https://doaj.org/article/707cceb0a4514b18b6f023ab2a79d79c
Publikováno v:
PLoS ONE, Vol 18, Iss 1 (2023)
When individuals face psychological difficulties that exceed their resources, consulting professionals for mental health treatment can be an effective way to overcome these difficulties. However, in general, only a few patients receive treatment for
Externí odkaz:
https://doaj.org/article/fca25a34da1a45e0a4ef56bd5f060fff
Publikováno v:
Comprehensive Psychiatry, Vol 109, Iss , Pp 152250- (2021)
Background:Firefighters are often exposed to terrible and dangerous scenes due to their duties, and thus have a high risk of developing posttraumatic stress disorder(PTSD). The purpose of the study is to examine the relationship between PTSD symptoms
Externí odkaz:
https://doaj.org/article/bd8392ed4ebb48a7b60206600aebe87d
Autor:
In-Hye Ham, Hye Jeong Oh, Hyejin Jin, Cheong A Bae, Sang-Min Jeon, Kyeong Sook Choi, Sang-Yong Son, Sang-Uk Han, Rolf A. Brekken, Dakeun Lee, Hoon Hur
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-14 (2019)
Abstract Background Although the tumor stroma in solid tumors like gastric cancer (GC) plays a crucial role in chemo-resistance, specific targets to inhibit the interaction between the stromal and cancer cells have not yet been utilized in clinical p
Externí odkaz:
https://doaj.org/article/8b81a477165944fd990dc1bf74836669
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Paraptosis is a type of programmed cell death that is characterized by dilation of the endoplasmic reticulum (ER) and/or mitochondria. Since paraptosis is morphologically and biochemically different from apoptosis, understanding its regulatory mechan
Externí odkaz:
https://doaj.org/article/e65afb4ca83d40a881493ec9a3d80b64
Publikováno v:
Annals of Occupational and Environmental Medicine, Vol 30, Iss 1, Pp 1-7 (2018)
Abstract Background Resilient individuals have a comprehensive ability to adapt to various life circumstances. Psychological resilience predicts an individual’s physiological response to stress. The 10-item Connor-Davidson Resilience Scale (CD-RISC
Externí odkaz:
https://doaj.org/article/8ad6adb4e3c54cec9d08db9699429cc3
Publikováno v:
Population Medicine. 5
Publikováno v:
Korean Academy of Addiction Psychiatry. 26:21-27
Publikováno v:
Biochemical and Biophysical Research Communications. 596:56-62
Despite the success of proteasome inhibitors (PIs) in treating hematopoietic malignancies, including multiple myeloma (MM), their clinical efficacy is limited in solid tumors. In this study, we investigated the involvement of the integrated stress re