Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kye Stachowski"'
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281876 (2023)
Neurofibromatosis Type 2 is an inherited disease characterized by Schwann cell tumors of cranial and peripheral nerves. The NF2 gene encodes Merlin, a member of the ERM family consisting of an N-terminal FERM domain, a central α-helical region, and
Externí odkaz:
https://doaj.org/article/f999f2a55ba541cbb2dca0312033a332
Autor:
Hong-Duc Phan, Andrew S Norris, Chen Du, Kye Stachowski, Bela H Khairunisa, Vaishnavi Sidharthan, Biswarup Mukhopadhyay, Mark P Foster, Vicki H Wysocki, Venkat Gopalan
Publikováno v:
Nucleic Acids Research. 50:8154-8167
RNase P is a ribonucleoprotein (RNP) that catalyzes removal of the 5 ' leader from precursor tRNAs in all domains of life. A recent cryo-EM study of Methanocaldococcus jannaschii (Mja) RNase P produced a model at 4.6-angstrom resolution in a dimeric
Publikováno v:
Nucleic acids research. 50(3)
Cre recombinase selectively recognizes DNA and prevents non-specific DNA cleavage through an orchestrated series of assembly intermediates. Cre recombines two loxP DNA sequences featuring a pair of palindromic recombinase binding elements and an asym
Neurofibromatosis Type 2 is an inherited disease characterized by Schwann cell tumors of cranial and peripheral nerves. The NF2 gene encodes Merlin, a member of the ERM family consisting of an N-terminal FERM domain, a central α-helical region and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7549b41334a0c9acaf11793c2a2f30d
https://doi.org/10.1101/2021.11.11.468247
https://doi.org/10.1101/2021.11.11.468247
Mechanistic understanding of the structural basis for DNA recombination in the Cre-loxP system has largely been guided by crystallographic structures of tetrameric synaptic complexes (intasomes). These structural and biochemical studies have suggeste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1494fc636dd15ed1b06996071b4304a4
https://doi.org/10.1101/2021.07.31.454597
https://doi.org/10.1101/2021.07.31.454597
Autor:
Kye Stachowski, Mark P. Foster, Deepak Kumar Yadav, Devante Potter, Aparna Unnikrishnan, Carlos Amero
Publikováno v:
Proc Natl Acad Sci U S A
Mechanistic understanding of DNA recombination in the Cre-loxP system has largely been guided by crystallographic structures of tetrameric synaptic complexes. Those studies have suggested a role for protein conformational dynamics that has not been w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::217fd3860191351a4497b9ac2c151469
https://europepmc.org/articles/PMC7547242/
https://europepmc.org/articles/PMC7547242/
Autor:
David Nichols, Timothy J. Brodribb, Nadia M. Atallah, Christof Lind, Chao Cai, Michael A. Geringer, Dietmar Geiger, Frances C. Sussmilch, Scott A. M. McAdam, Jo Ann Banks, Rainer Hedrich, Kye Stachowski
Publikováno v:
Proceedings of the National Academy of Sciences. 113:12862-12867
Sexual reproduction in animals and plants shares common elements, including sperm and egg production, but unlike animals, little is known about the regulatory pathways that determine the sex of plants. Here we use mutants and gene silencing in a fern