Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kyaw Z. Thein"'
Autor:
Kyaw Z. Thein, Sarina A. Piha-Paul, Apostolia Tsimberidou, Daniel D. Karp, Filip Janku, Siqing Fu, Vivek Subbiah, David S. Hong, Timothy A. Yap, Jatin Shah, Denái R. Milton, Lacey McQuinn, Jing Gong, Yanyan Tran, Brett W. Carter, Rivka Colen, Funda Meric-Bernstam, Aung Naing
Publikováno v:
Experimental Hematology & Oncology, Vol 10, Iss 1, Pp 1-6 (2021)
Abstract Selinexor, an oral selective inhibitor of nuclear export (SINE), was demonstrated to hinder the DNA damage repair (DDR) system by reducing DDR proteins while enhancing the killing of cancer cells by DDR-based therapeutics in vivo studies. In
Externí odkaz:
https://doaj.org/article/c459d13c2a2d4dd98828b2e651417c38
Autor:
Kyaw Z. Thein, Siqing Fu, Filip Janku, Apostolia M. Tsimberidou, Sarina A. Piha-Paul, Daniel D. Karp, Jatin Shah, Denái R. Milton, Jing Gong, Selma Sulovic, Lacey McQuinn, Bettzy A. Stephen, Rivka R. Colen, Brett W. Carter, Funda Meric-Bernstam, Aung Naing
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Pp 10-12 (2022)
Externí odkaz:
https://doaj.org/article/dbd595d620e44cfc834f3c0087d00433
Publikováno v:
eJHaem, Vol 2, Iss 1, Pp 112-117 (2021)
Abstract Acalabrutinib is a second generation Bruton's tyrosine kinase inhibitor and was recently approved in the treatment of chronic lymphocytic leukaemia. We undertook a systematic review and meta‐analysis of randomised controlled trials to dete
Externí odkaz:
https://doaj.org/article/628cae176fa847eda104c3f0ba101821
Publikováno v:
eJHaem, Vol 1, Iss 1, Pp 262-266 (2020)
Abstract The use of the CD38 monoclonal antibody daratumumab in combination with standard myeloma chemotherapy regimens has been studied extensively in recent years. We undertook an updated meta‐analysis of phase III randomized controlled trials (R
Externí odkaz:
https://doaj.org/article/383c872cf44548b1929ff7f96cee933d
Autor:
Vivek Subbiah, Ecaterina Ileana Dumbrava, Yunfang Jiang, Kyaw Z. Thein, Aung Naing, David S. Hong, Siqing Fu, Sarina A. Piha-Paul, Apostolia M. Tsimberidou, Filip Janku, Funda Meric-Bernstam, Razelle Kurzrock, Gerald Falchook
Publikováno v:
Experimental Hematology & Oncology, Vol 9, Iss 1, Pp 1-8 (2020)
Abstract Background Angiogenesis and activation of the epidermal growth factor (EGFR) pathway play an essential role in tumor proliferation and metastasis. Targeting angiogenesis or EGFR alone does not yield adequate tumor control in most solid tumor
Externí odkaz:
https://doaj.org/article/298df416fe5646c49f0ad3822da218df
Autor:
A. Dimitrios Colevas, John J Park, Bruno Fang, Jiang Shao, Lance U'Ren, Jared Odegard, Indu Lal, Minh Phan, Kyaw Z. Thein, Douglas Adkins
Publikováno v:
Journal of the National Comprehensive Cancer Network. 20:CLO22-041
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3a7b9946afed9df91a792d1c3b99ddf
https://doi.org/10.6004/jnccn.2021.7170
https://doi.org/10.6004/jnccn.2021.7170
Publikováno v:
Cureus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0066f4178aa5669caa6de4e47cfe0de4
https://doi.org/10.7759/cureus.31798
https://doi.org/10.7759/cureus.31798
Autor:
Kyaw Z, Thein, Amadeo B, Biter, Kimberly C, Banks, Andrew W, Duda, Jennifer, Saam, Jason, Roszik, Filip, Janku, Ferdinandos, Skoulidis, John V, Heymach, Scott, Kopetz, Funda, Meric-Bernstam, David S, Hong
Publikováno v:
JCO precision oncology. 6
We conducted a 5-year retrospective review ofOur study demonstrates the feasibility of using circulating tumor DNA to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8f6a9bb45f0d84414799e5cb833c9976
https://pubmed.ncbi.nlm.nih.gov/35862868
https://pubmed.ncbi.nlm.nih.gov/35862868
Autor:
Kyaw Z. Thein, Amadeo B. Biter, Kimberly C. Banks, Andrew W. Duda, Jennifer Saam, Jason Roszik, Filip Janku, Ferdinandos Skoulidis, John V. Heymach, Scott Kopetz, Funda Meric-Bernstam, David S. Hong
Publikováno v:
JCO Precision Oncology.
PURPOSE KRAS is the most mutated proto-oncogene that has been identified in cancer, and treatment of patients with KRAS mutations remains an arduous challenge. Recently, KRAS G12C mutation has attracted special interest because it is now considered p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00033e4ca2706a2354048b113a47b19f
https://doi.org/10.1200/po.21.00547
https://doi.org/10.1200/po.21.00547
Autor:
Benjamin Garmezy, Jinesh Gheeya, Heather Y. Lin, Yuefan Huang, Taebeom Kim, Xianli Jiang, Kyaw Z. Thein, Patrick G. Pilié, Fadl Zeineddine, Wanlin Wang, Kenna R. Shaw, Jordi Rodon, John Paul Shen, Ying Yuan, Funda Meric-Bernstam, Ken Chen, Timothy A. Yap
Publikováno v:
JCO Precision Oncology.
PURPOSEDNA polymerase epsilon is critical to DNA proofreading and replication. Mutations in POLE have been associated with hypermutated tumors and antitumor response to immune checkpoint inhibitor (ICI) therapy. We present a clinicopathologic analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::432dabc6824d19f5958d922129dcf378
https://doi.org/10.1200/po.21.00267
https://doi.org/10.1200/po.21.00267