Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Kyathanahalli S, Janardhan"'
Autor:
Jian Liu, Tianyuan Wang, Chad J. Creighton, San-Pin Wu, Madhumita Ray, Kyathanahalli S. Janardhan, Cynthia J. Willson, Sung-Nam Cho, Patricia D. Castro, Michael M. Ittmann, Jian-Liang Li, Roger J. Davis, Francesco J. DeMayo
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
LKB1 is frequently mutated in lung squamous cell carcinomas. Here, the authors show that sole LKB1 depletion is sufficient to drive the development of this cancer, where downstream defective MKK7-JNK1/2 signalling activates the ∆Np63/p63 pathway to
Externí odkaz:
https://doaj.org/article/3c4a64d307334e7da067be3231521b05
Autor:
Gregory A. Krane, Keith R. Shockley, David E. Malarkey, Andrew D. Miller, C. Ryan Miller, Debra A. Tokarz, Heather L. Jensen, Kyathanahalli S. Janardhan, Matthew Breen, Christopher L. Mariani
Publikováno v:
Veterinary and Comparative Oncology. 20:881-889
Histopathological evaluation of tumours is a subjective process, but studies of inter-pathologist agreement are uncommon in veterinary medicine. The Comparative Brain Tumour Consortium (CBTC) recently published diagnostic criteria for canine gliomas.
Autor:
Anton M. Jetten, Kyathanahalli S. Janardhan, John E. French, Michael A. Resnick, Daniel Menendez, Zhengyu Yin
PDF file - 59K, Increased sensitivity of RAP80-/- MEFs to DNA damaging agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525f36c63f50d87aa07de41f69b94724
https://doi.org/10.1158/0008-5472.22394928
https://doi.org/10.1158/0008-5472.22394928
Autor:
Anton M. Jetten, Kyathanahalli S. Janardhan, John E. French, Michael A. Resnick, Daniel Menendez, Zhengyu Yin
PDF file - 870K, Increased chromosomal instability in RAP80-/- iMEFs after DNA damage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a3b0bc8f531d80efd8781fcd8fe53a
https://doi.org/10.1158/0008-5472.22394925.v1
https://doi.org/10.1158/0008-5472.22394925.v1
Autor:
Anton M. Jetten, Kyathanahalli S. Janardhan, John E. French, Michael A. Resnick, Daniel Menendez, Zhengyu Yin
PDF file - 518K, RAP80-/- MEFs undergo early senescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb8fac0f31eb16710fbf40ed04f2f28
https://doi.org/10.1158/0008-5472.22394934.v1
https://doi.org/10.1158/0008-5472.22394934.v1
Autor:
Anton M. Jetten, Kyathanahalli S. Janardhan, John E. French, Michael A. Resnick, Daniel Menendez, Zhengyu Yin
PDF file - 34K, Comparison of the IR sensitivity between WT and RAP80-/- mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d5f99c4c2af25987e3c1082e2e9c247
https://doi.org/10.1158/0008-5472.22394931.v1
https://doi.org/10.1158/0008-5472.22394931.v1
Autor:
Anton M. Jetten, Kyathanahalli S. Janardhan, John E. French, Michael A. Resnick, Daniel Menendez, Zhengyu Yin
PDF file - 276K, Histopathological examination of tumor tissues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52beeb6d6767eedc34c0b2ce06ced676
https://doi.org/10.1158/0008-5472.22394922.v1
https://doi.org/10.1158/0008-5472.22394922.v1
Autor:
Anton M. Jetten, Kyathanahalli S. Janardhan, John E. French, Michael A. Resnick, Daniel Menendez, Zhengyu Yin
PDF file - 96K, Generation of RAP80 null Mice and Real-time qRT-PCR analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088ebc2586b439ed0fc420bc07765e42
https://doi.org/10.1158/0008-5472.22394916
https://doi.org/10.1158/0008-5472.22394916
Autor:
Kyathanahalli S. Janardhan, Radhakrishna Sura, Smita Salian-Mehta, Thierry Flandre, Xavier Palazzi, Doris Zane, Bhanu Singh, Binod Jacob, Renee Rosemary Hukkanen, Muthafar Al-Haddawi, Bindu Bennet, Victoria Laast, Donna Lee, Richard Peterson, Annette Romeike, Frederic Schorsch, Magali Guffroy
Publikováno v:
Toxicologic pathology. 50(8)
Nonclinical toxicology studies that are required to support human clinical trials of new drug candidates are generally conducted in a rodent and a non-rodent species. These studies typically contain a vehicle control group and low, intermediate, and