Tspyl2 Loss-of-Function Causes Neurodevelopmental Brain and Behavior Abnormalities in Mice

Autor: Siu Yuen Chan, Grainne M. McAlonan, Abby Y. Ding, Qi Li, Ed X. Wu, Tomy C. K. Hui, Kwun Kk Wong, Yu On Leung, Pak C. Sham, Ran Wei, Siew E. Chua, Charlton Cheung

Publikováno v: Behavior Genetics
Li, Q, Chan, S Y, Wong, K K, Wei, R, Leung, Y O, Ding, A Y, Hui, T C K, Cheung, C, Chua, S E, Sham, P C, Wu, E X & McAlonan, G M 2016, ' Tspyl2 Loss-of-Function Causes Neurodevelopmental Brain and Behavior Abnormalities in Mice ', Behavior Genetics, pp. 1-9 . https://doi.org/10.1007/s10519-015-9777-8

Testis specific protein, Y-encoded-like 2 (TSPYL2) regulates the expression of genes encoding glutamate receptors. Glutamate pathology is implicated in neurodevelopmental conditions such as autism spectrum disorder, attention deficit hyperactivity di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77830c5c6bad9bb32aee07162489594b
http://europepmc.org/articles/PMC4886156