Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Kwonho, Hong"'
Autor:
HeeJi Lee, Dong Wook Han, Hyeonwoo La, Chanhyeok Park, Kiye Kang, Ohbeom Kwon, Sang Jun Uhm, Hyuk Song, Jeong Tae Do, Youngsok Choi, Kwonho Hong
Publikováno v:
Animal Bioscience, Vol 37, Iss 9, Pp 1635-1643 (2024)
Objective Disruptor of telomeric silencing 1-like (DOT1L) is the only known histone H3K79 methyltransferase essential for the development of the embryonic cardiovascular system, including the heart, blood vessels, and lymphatic vessels, through trans
Externí odkaz:
https://doaj.org/article/b27f067bf8364bfc8bea1b13712ffa32
Autor:
Hyeonji Lee, Dong Wook Han, Seonho Yoo, Ohbeom Kwon, Hyeonwoo La, Chanhyeok Park, Heeji Lee, Kiye Kang, Sang Jun Uhm, Hyuk Song, Jeong Tae Do, Youngsok Choi, Kwonho Hong
Publikováno v:
Animal Bioscience, Vol 37, Iss 6, Pp 1021-1030 (2024)
Objective R-loops are DNA:RNA triplex hybrids, and their metabolism is tightly regulated by transcriptional regulation, DNA damage response, and chromatin structure dynamics. R-loop homeostasis is dynamically regulated and closely associated with gen
Externí odkaz:
https://doaj.org/article/16c49cd087aa4c91b5bdc0e4cb3fd2bb
Autor:
Kyung Min Lim, Sehee Kim, Jeonghun Yeom, Yujin Choi, Yoonjoo Lee, Jongyub An, Minchan Gil, Ahmed Abdal Dayem, Kyeongseok Kim, Geun-Ho Kang, Aram Kim, Kwonho Hong, Kyunggon Kim, Ssang-Goo Cho
Publikováno v:
Journal of Advanced Research, Vol 47, Iss , Pp 57-74 (2023)
Introduction: Mesenchymal stromal cells (MSCs) release extracellular vesicles (MSC-EVs) containing various cargoes. Although MSC-EVs show significant therapeutic effects, the low production of EVs in MSCs hinders MSC-EV-mediated therapeutic developme
Externí odkaz:
https://doaj.org/article/4da602a858a8462786add44d162a5486
Autor:
Nguyen Xuan Thang, Dong Wook Han, Chanhyeok Park, Hyeonji Lee, Hyeonwoo La, Seonho Yoo, Heeji Lee, Sang Jun Uhm, Hyuk Song, Jeong Tae Do, Kyoung Sik Park, Youngsok Choi, Kwonho Hong
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The aberrant function of ATP-dependent chromatin remodeler INO80 has been implicated in multiple types of cancers by altering chromatin architecture and gene expression; however, the underlying mechanism of the functional involvement of INO80 mutatio
Externí odkaz:
https://doaj.org/article/4e3831288ec0422f85f4d7a4a9c0e81a
Autor:
Hyunjin Yoo, Hyeonwoo La, Chanhyeok Park, Seonho Yoo, Hyeonji Lee, Hyuk Song, Jeong Tae Do, Youngsok Choi, Kwonho Hong
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Epigenetic mechanisms are mandatory for endothelial called lymphangioblasts during cardiovascular development. Dot1l-mediated gene transcription in mice is essential for the development and function of lymphatic ECs (LECs). The role of Dot1l in the d
Externí odkaz:
https://doaj.org/article/f3098734b54144e0916b76357dc31c76
Autor:
Xuerui Yao, Ji Hyun Kang, Kee-Pyo Kim, Hyogeun Shin, Zhe-Long Jin, Hao Guo, Yong-Nan Xu, Ying-Hua Li, Sai Hali, Jeongwoo Kwon, Hyeonwoo La, Chanhyeok Park, Yong-June Kim, Lin Wang, Kwonho Hong, Qilong Cao, Il-Joo Cho, Nam-Hyung Kim, Dong Wook Han
Publikováno v:
Stem Cells International, Vol 2023 (2023)
Brain organoids have been considered as an advanced platform for in vitro disease modeling and drug screening, but numerous roadblocks exist, such as lack of large-scale production technology and lengthy protocols with multiple manipulation steps, im
Externí odkaz:
https://doaj.org/article/a429f20de04345d09ff67eca862e03f6
Autor:
Jae-Hoon Song, Joonhyuk Choi, Yean-Ju Hong, Hyeonwoo La, Tae-Kyung Hong, Kwonho Hong, Jeong-Tae Do
Publikováno v:
Cells, Vol 11, Iss 20, p 3266 (2022)
As a novel cell type from eight-cell-stage embryos, extended pluripotent stem cells (EPSCs) are known for diverse differentiation potency in both extraembryonic and embryonic lineages, suggesting new possibilities as a developmental research model. A
Externí odkaz:
https://doaj.org/article/cf82151e663e497c9f20502b6ff2a505
Autor:
Ah Reum Lee, Kwonho Hong, Seo Hye Choi, Chanhyeok Park, Jae Kyun Park, Jin Il Lee, Jae Il Bang, Dong-Won Seol, Jeoung Eun Lee, Dong Ryul Lee
Publikováno v:
Stem Cell Reports, Vol 12, Iss 3, Pp 545-556 (2019)
Summary: Cryopreservation has a negative effect on the quality of oocytes and may be closely associated with increased levels of reactive oxygen species (ROS) and apoptotic events. The purpose of the present study was to evaluate the detrimental effe
Externí odkaz:
https://doaj.org/article/c165e111b8d84df9803702f08ef50abe
Autor:
Hye Yeon Choi, Gwang-Mo Yang, Ahmed Abdal Dayem, Subbroto Kumar Saha, Kyeongseok Kim, Youngbum Yoo, Kwonho Hong, Jin-Hoi Kim, Cassian Yee, Kyung-Mi Lee, Ssang-Goo Cho
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-20 (2019)
Abstract Background Epithelial-mesenchymal transition (EMT) occurs in the tumor microenvironment and presents an important mechanism of tumor cell intravasation, stemness acquisition, and metastasis. During metastasis, tumor cells enter the circulati
Externí odkaz:
https://doaj.org/article/c38d7be72d0943af95e95bd732e2613d
Autor:
Hyeonwoo La, Hyunjin Yoo, Young Bin Park, Nguyen Xuan Thang, Chanhyeok Park, Seonho Yoo, Hyeonji Lee, Youngsok Choi, Hyuk Song, Jeong Tae Do, Kwonho Hong
Publikováno v:
Cells, Vol 11, Iss 10, p 1692 (2022)
The lymphatic system is critical for maintaining the homeostasis of lipids and interstitial fluid and regulating the immune cell development and functions. Developmental anomaly-induced lymphatic dysfunction is associated with various pathological co
Externí odkaz:
https://doaj.org/article/5adba35458b44aa5901ca951a539be40