Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Kwon-Yul Ryu"'
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-4 (2024)
Abstract Lipocalin-2 (Lcn2), a protein secreted by immune-activated cells, including reactive astrocytes, is detrimental to the brain and induces neurodegeneration. We previously showed that Lcn2 levels are reduced in primary mouse astrocytes after t
Externí odkaz:
https://doaj.org/article/f63bd1db1c704716b60f8571fae9ea94
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 2, Pp 331-335 (2024)
Many types of plastic products, including polystyrene, have long been used in commercial and industrial applications. Microplastics and nanoplastics, plastic particles derived from these plastic products, are emerging as environmental pollutants that
Externí odkaz:
https://doaj.org/article/d39f95dd2e0c41a1a7f961fe3c202df4
Autor:
Byung-Kwon Jung, Kwon-Yul Ryu
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 10, Pp 2138-2146 (2023)
Abstract Glial cell activation precedes neuronal cell death during brain aging and the progression of neurodegenerative diseases. Under neuroinflammatory stress conditions, lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin
Externí odkaz:
https://doaj.org/article/975030655b53469aba5007befe320fd9
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15864 (2023)
Astrocytes and microglia, the most abundant glial cells in the central nervous system, are involved in maintaining homeostasis in the brain microenvironment and in the progression of various neurological disorders. Lipocalin-2 (LCN2) is a small secre
Externí odkaz:
https://doaj.org/article/95b1b4043b2540b395c371b7790c91bb
Autor:
Bitnara Han, Byung-Kwon Jung, So-Hyun Park, Kyu Jin Song, Muhammad Ayaz Anwar, Kwon-Yul Ryu, Kwang Pyo Kim
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Testis development, including early embryonic gonad formation and late postnatal spermatogenesis, is essential for the reproduction of higher metazoans to generate fertile gametes, called sperm. We have previously reported that the polyubiqu
Externí odkaz:
https://doaj.org/article/b6105ed108a5483c90c304757f89a565
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-4 (2020)
Abstract Neurodegenerative diseases are characterized by progressive cognitive decline and the loss of neurons in the central nervous system; many are also characterized by abnormal aggregation of misfolded proteins. Ubiquitin (Ub) is a eukaryotic pr
Externí odkaz:
https://doaj.org/article/9530b79259b74a699f6b0c243ff3723e
Autor:
Chul-Woo Park, Kwon-Yul Ryu
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 9, Pp 1781-1782 (2021)
Externí odkaz:
https://doaj.org/article/aadcf7eb8e2b43a78ef4558a8c3a63cc
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 2094 (2021)
Polystyrene (PS) nanoplastic exposure has been shown to affect the viability of neuronal cells isolated from mouse embryonic brains. However, the viability of mouse embryonic fibroblasts (MEFs) was not affected although PS nanoplastics accumulated in
Externí odkaz:
https://doaj.org/article/2128e77b7450463d973a0d19eaa91d87
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3168 (2019)
Ubiquitin is required under both normal and stress conditions. Under stress conditions, upregulation of the polyubiquitin gene UBC is essential to meet the requirement of increased ubiquitin levels to confer stress resistance. However, UBC upregulati
Externí odkaz:
https://doaj.org/article/f1b2311d420f4dcc9e6f815a8583f3be
Autor:
Kahori Shiba-Fukushima, Taku Arano, Gen Matsumoto, Tsuyoshi Inoshita, Shigeharu Yoshida, Yasushi Ishihama, Kwon-Yul Ryu, Nobuyuki Nukina, Nobutaka Hattori, Yuzuru Imai
Publikováno v:
PLoS Genetics, Vol 10, Iss 12, p e1004861 (2014)
The kinase PINK1 and the E3 ubiquitin (Ub) ligase Parkin participate in mitochondrial quality control. The phosphorylation of Ser65 in Parkin's ubiquitin-like (UBl) domain by PINK1 stimulates Parkin activation and translocation to damaged mitochondri
Externí odkaz:
https://doaj.org/article/fe100669f56a46c7950072279f3e37e0