Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Kwon Sik Park"'
Autor:
Bongjun Kim, Yuanjian Huang, Kyung-Pil Ko, Shengzhe Zhang, Gengyi Zou, Jie Zhang, Moon Jong Kim, Danielle Little, Lisandra Vila Ellis, Margherita Paschini, Sohee Jun, Kwon-Sik Park, Jichao Chen, Carla Kim, Jae-Il Park
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Cell plasticity, changes in cell fate, is crucial for tissue regeneration. In the lung, failure of regeneration leads to diseases, including fibrosis. However, the mechanisms governing alveolar cell plasticity during lung repair remain elusi
Externí odkaz:
https://doaj.org/article/dc073faf3c6b41ac9927b12392b90d9a
Autor:
Bongjun Kim, Shengzhe Zhang, Yuanjian Huang, Kyung-Pil Ko, Youn-Sang Jung, Jinho Jang, Gengyi Zou, Jie Zhang, Sohee Jun, Kee-Beom Kim, Kwon-Sik Park, Jae-Il Park
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114286- (2024)
Summary: Tumor cell plasticity contributes to intratumoral heterogeneity and therapy resistance. Through cell plasticity, some lung adenocarcinoma (LUAD) cells transform into neuroendocrine (NE) tumor cells. However, the mechanisms of NE cell plastic
Externí odkaz:
https://doaj.org/article/7beabc5633f54eef9bcd464bc524689b
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 12, Pp 1-13 (2019)
Small cell lung cancer: Genome insights for improving treatment Alterations in the small cell lung cancer (SCLC) genome are critical for disease progression and relapse. A complete map of the genome in cancerous cells would greatly improve the chance
Externí odkaz:
https://doaj.org/article/481293375a814f82a5796626219ba5a0
Publikováno v:
Experimental & Molecular Medicine. 54:2118-2127
Tumor suppressor genes (TSGs) are often involved in maintaining homeostasis. Loss of tumor suppressor functions causes cellular plasticity that drives numerous types of cancer, including small-cell lung cancer (SCLC), an aggressive type of lung cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c20ce882558be5f27f0f4fd6b2e707
https://doi.org/10.1038/s12276-022-00905-x
https://doi.org/10.1038/s12276-022-00905-x
Autor:
Marie Pereira, Jeong-Hun Ko, John Logan, Hayley Protheroe, Kee-Beom Kim, Amelia Li Min Tan, Peter I Croucher, Kwon-Sik Park, Maxime Rotival, Enrico Petretto, JH Duncan Bassett, Graham R Williams, Jacques Behmoaras
Publikováno v:
eLife, Vol 9 (2020)
Functional characterisation of cell-type-specific regulatory networks is key to establish a causal link between genetic variation and phenotype. The osteoclast offers a unique model for interrogating the contribution of co-regulated genes to in vivo
Externí odkaz:
https://doaj.org/article/3598a6a41082456e82266d54eb35c4ad
Autor:
Kee-Beom Kim, Dong-Wook Kim, Youngchul Kim, Jun Tang, Nicole Kirk, Yongyu Gan, Bongjun Kim, Bingliang Fang, Jae-ll Park, Yi Zheng, Kwon-Sik Park
Publikováno v:
Cancer Res
WNT signaling represents an attractive target for cancer therapy due to its widespread oncogenic role. However, the molecular players involved in WNT signaling and the impact of their perturbation remain unknown for numerous recalcitrant cancers. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e1f5dcd41160609124d2d48613fbd0
https://doi.org/10.1158/0008-5472.can-22-1170
https://doi.org/10.1158/0008-5472.can-22-1170
Autor:
Bongjun Kim, Shengzhe Zhang, Yuanjian Huang, Kyung-Pil Ko, Gengyi Zou, Jie Zhang, Sohee Jun, Kee-Beom Kim, Youn-Sang Jung, Kwon-Sik Park, Jae-Il Park
Publikováno v:
bioRxiv
Tumor cell plasticity contributes to intratumoral heterogeneity and therapy resistance. Through cell plasticity, lung adenocarcinoma (LUAD) cells transform into neuroendocrinal (NE) tumor cells. However, the mechanisms of NE cell plasticity remain un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49c0202ce763c03300f67d882d9dd9e
https://europepmc.org/articles/PMC10153265/
https://europepmc.org/articles/PMC10153265/
Autor:
Monte M. Winslow, Julien Sage, William J. Greenleaf, Anshul Kundaje, Matthias Preusser, Kwon-Sik Park, H. Christian Reinhardt, Anna Schmitt, Anna S. Berghoff, Christina S. Kong, Shirley Kwok, Jing Shan Lim, Nadine S. Jahchan, Jeffrey M. Granja, Youcef Ouadah, Jennifer J. Brady, Andrea C. Chaikovsky, Peyton G. Greenside, Sarah K. Denny, Dian Yang
table_S1_SCLC_cre model_pathology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f34e89ef81614c1767731f078cefd4c
https://doi.org/10.1158/2159-8290.22532194.v1
https://doi.org/10.1158/2159-8290.22532194.v1
Autor:
David MacPherson, Kwon-Sik Park, Hamid Bolouri, Adi F. Gazdar, Smitha P.S. Pillai, Colin T. Dunn, Kee-Beom Kim, Ali H. Ibrahim, Nan Wu, Emily Eastwood, Dong-Wook Kim, Arnaud Augert, Deshui Jia
Supplementary tables S1 to S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2980c42ecca9ece263595a071b8307c2
https://doi.org/10.1158/2159-8290.22531804
https://doi.org/10.1158/2159-8290.22531804
Autor:
Monte M. Winslow, Julien Sage, William J. Greenleaf, Anshul Kundaje, Matthias Preusser, Kwon-Sik Park, H. Christian Reinhardt, Anna Schmitt, Anna S. Berghoff, Christina S. Kong, Shirley Kwok, Jing Shan Lim, Nadine S. Jahchan, Jeffrey M. Granja, Youcef Ouadah, Jennifer J. Brady, Andrea C. Chaikovsky, Peyton G. Greenside, Sarah K. Denny, Dian Yang
All supplementary figures (S1-S17)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91bbd3f1e44f1b89db6fba9a80eaf435
https://doi.org/10.1158/2159-8290.22532197
https://doi.org/10.1158/2159-8290.22532197