Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kwok-Ling Kam"'
Autor:
Matthew McCord, Alicia Steffens, Rodrigo Javier, Kwok-Ling Kam, Kathleen McCortney, Craig Horbinski
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-8 (2020)
Abstract A subset of gliomas has DNA repair defects that lead to hypermutated genomes. While such tumors are resistant to alkylating chemotherapies, they may also express more mutant neoantigens on their cell surfaces, and thus be more responsive to
Externí odkaz:
https://doaj.org/article/7a7eb0e3e82947c48f7eb930e5d8a6f8
Autor:
Qinwen Mao, Nabeel R. Yaseen, Liron Barnea Slonim, Kwok-Ling Kam, Daniel J. Brat, Rimas V. Lukas, Sarah M. Brooker, Adam M. Sonabend
Publikováno v:
Journal of Clinical Neuroscience. 81:61-64
Establishing the pathologic diagnosis of central nervous system (CNS) lymphoma can be challenging, yet management of this potentially curable disease depends heavily on it. One avoidable impediment to obtaining an accurate and timely diagnosis is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2a63deff63c8ef5055a987ce21039f8
https://doi.org/10.1016/j.jocn.2020.09.014
https://doi.org/10.1016/j.jocn.2020.09.014
Autor:
Sachie Ikegami, Daniel J. Brat, Kwok Ling Kam, Marina N. Nikiforova, Christina L. Appin, Rimas V. Lukas, Craig Horbinski, Somak Roy, Qinwen Mao
Publikováno v:
J Neuropathol Exp Neurol
The power and widespread use of next-generation sequencing (NGS) in surgical neuropathology has raised questions as to whether NGS might someday fully supplant histologic-based examination. We therefore sought to determine the feasibility of relying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6d8d96577059888d390ee02b92b29e
https://doi.org/10.1093/jnen/nlaa044
https://doi.org/10.1093/jnen/nlaa044
Publikováno v:
World Neurosurgery. 138:313-316
Background Autologous bone resorption is a frequent complication of cranioplasty, often necessitating reoperation. The etiology of this phenomenon is unknown, although it has recently been associated with indolent Propionibacterium acnes infection. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71a433c7e1589f5f243e5ad77b75f542
https://doi.org/10.1016/j.wneu.2020.03.077
https://doi.org/10.1016/j.wneu.2020.03.077
Autor:
Kwok Ling Kam, Alicia Steffens, Craig Horbinski, Matthew McCord, Kathleen McCortney, Rodrigo Javier
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-8 (2020)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
A subset of gliomas has DNA repair defects that lead to hypermutated genomes. While such tumors are resistant to alkylating chemotherapies, they may also express more mutant neoantigens on their cell surfaces, and thus be more responsive to immunothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9f660c50a748e3141930f4882f7ec4
https://doaj.org/article/7a7eb0e3e82947c48f7eb930e5d8a6f8
https://doaj.org/article/7a7eb0e3e82947c48f7eb930e5d8a6f8
Autor:
Lucas Santana-Santos, Kwok Ling Kam, David Dittmann, Stephanie De Vito, Matthew McCord, Pouya Jamshidi, Hailie Fowler, Xinkun Wang, Alan M. Aalsburg, Daniel J. Brat, Craig Horbinski, Lawrence J. Jennings
Publikováno v:
The Journal of molecular diagnostics : JMD. 24(8)
The 2021 WHO Classification of Tumors of the Central Nervous System includes several tumor types and subtypes for which the diagnosis is at least partially reliant on utilization of whole genome methylation profiling. The current approach to array DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b49da3b7603884bb094a43219d5ff2
https://pubmed.ncbi.nlm.nih.gov/35605901
https://pubmed.ncbi.nlm.nih.gov/35605901
Autor:
Sean Grimm, Milan G. Chheda, Kwok Ling Kam, Jeffrey Raizer, Sean Sachdev, Alicia Steffens, Karan Dixit, Tim J. Kruser, Rimas V. Lukas, Michael Drumm, Roger Stupp, Craig Horbinski, Priya Kumthekar, Rodrigo Javier, Matthew McCord, Kathleen McCortney
Publikováno v:
Neuro-Oncology. 22:470-479
Background Progress in extending the survival of glioblastoma (GBM) patients has been slow. A better understanding of why patient survival remains poor is critical to developing new strategies. Postmortem studies on GBM can shed light on why patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2abb4e6a40d35837d5c9176f2e96d113
https://doi.org/10.1093/neuonc/noz216
https://doi.org/10.1093/neuonc/noz216
Autor:
Sheeja Aravindan, Marcellus J. Banworth, Kar Ming Fung, Guangpu Li, Paige Parrack, Kwok-Ling Kam
Publikováno v:
Methods in Molecular Biology ISBN: 9781071613450
Methods Mol Biol
Methods Mol Biol
Rab GTPases are essentially molecular switches. They serve as master regulators in intracellular membrane trafficking from the formation and transport of vesicles at the originating organelle to its fusion to the membrane at the target organelle. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c4edebc085093af5900edcc9b0c6bd
https://doi.org/10.1007/978-1-0716-1346-7_19
https://doi.org/10.1007/978-1-0716-1346-7_19
Autor:
Deepak Kanojia, Jawad Fares, Krishan Kumar, Alex Cordero, Ting Xiao, Irina V. Balyasnikova, Annie Xiao, Maciej S. Lesniak, Jason Miska, Kwok-Ling Kam, Katarzyna C. Pituch, Solomiia Savchuk, Atique Ahmed, Peng Zhang, Craig Horbinski, Wojciech K. Panek
Publikováno v:
Sci Transl Med
Metastases from primary breast cancer result in poor survival. βIII-tubulin (TUBB3) has been established as a therapeutic target for breast cancer metastases specifically to the brain. In this study, we conducted a systematic analysis to determine t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e03d4ae33c8e4baeeef8eb4102ef207
https://doi.org/10.1126/scitranslmed.aax2879
https://doi.org/10.1126/scitranslmed.aax2879
Autor:
Linda Cooley, Adrian M. Dubuc, Jennifer J.D. Morrissetter, Robyn Sussman, Pamela Rathbun, Kai Lee Yap, Liming Bao, Daynna L. Wolff, Cris Ida, Madina Sukhanova, Kwok Ling Kam, Craig Horbinski, Lawrence Jennings, Melissa Gener, Kevin Ginn, David Meredith, Xinyan Lu
Publikováno v:
Cancer Genetics. :1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f83cae0c7531655bfed50f0af3583d55
https://doi.org/10.1016/j.cancergen.2021.05.015
https://doi.org/10.1016/j.cancergen.2021.05.015