Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Kwok-Ho Chan"'
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30547 (2012)
Maturation of [NiFe]-hydrogenase requires the insertion of iron, cyanide and carbon monoxide, followed by nickel, to the catalytic core of the enzyme. Hydrogenase maturation factor HypB is a metal-binding GTPase that is essential for the nickel deliv
Externí odkaz:
https://doaj.org/article/50d1ae8da2a34198bf1ad2a8d96b364b
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32592 (2012)
The active site of [NiFe]-hydrogenase contains nickel and iron coordinated by cysteine residues, cyanide and carbon monoxide. Metal chaperone proteins HypA and HypB are required for the nickel insertion step of [NiFe]-hydrogenase maturation. How HypA
Externí odkaz:
https://doaj.org/article/d33f4c456d7448d483a7706f195d5615
Autor:
Kwok-Ho Chan, 陳國顥
104
The health impact of air pollution on human is large, so Taiwan EPA (Environmental Protection Administration) proposed air pollution index PSI (Pollutant Standards Index) in 1993, to remind people the impact of air pollution. PSI is calculat
The health impact of air pollution on human is large, so Taiwan EPA (Environmental Protection Administration) proposed air pollution index PSI (Pollutant Standards Index) in 1993, to remind people the impact of air pollution. PSI is calculat
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/54650569567143919966
Autor:
Kwok Ho Chan, Wangnong Liao
Publikováno v:
International Journal of Asian Social Science. 12:308-317
International transfers in China are mostly from adult children to elderly parents. Using data from the China Health and Retirement Longitudinal Study (CHARLS), this study explores the motives of intergenerational transfers in China. Understanding th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0a2ee97247333f7afa3fbcd15ea633f
https://doi.org/10.55493/5007.v12i8.4562
https://doi.org/10.55493/5007.v12i8.4562
Autor:
Vesna Vetma, Kristin M. Riching, Satomi Imaide, Marjeta Urh, Claire Whitworth, Chiara Maniaci, Angus D. Cowan, Nicole Trainor, Sarah D. Mahan, Alessio Ciulli, Andrea Testa, Nancy Murphy, Conner Craigon, Kwok-Ho Chan, Nikolai Makukhin, Scott J. Hughes, Danette L. Daniels
Publikováno v:
Nature chemical biology
Bivalent proteolysis-targeting chimeras (PROTACs) drive protein degradation by simultaneously binding a target protein and an E3 ligase and forming a productive ternary complex. We hypothesized that increasing binding valency within a PROTAC could en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48142d6a1b031c2e4ceee52a00283704
https://doi.org/10.1038/s41589-021-00878-4
https://doi.org/10.1038/s41589-021-00878-4
Autor:
EDDIE CHI LEUNG CHEUNG1 clcheung@hkmu.edu.hk, YIU CHUNG MA1 ycma@hkmu.edu.hk, KWOK HO CHAN1 kwhchan@hkmu.edu.hk
Publikováno v:
China Perspectives. 2024, Issue 137, p7-19. 13p.
Autor:
Sascha Röth, Bill Carton, Preethi S. Sathyamurthi, Matthew Watt, Thomas J. Macartney, Kwok-Ho Chan, Albert Isidro-Llobet, Agnieszka Konopacka, Markus A. Queisser, Gopal Sapkota
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f92f5a0d6faeac4334957fc0b7a5b84
https://doi.org/10.2139/ssrn.4214930
https://doi.org/10.2139/ssrn.4214930
Autor:
Sarah D. Mahan, Kristin M. Riching, Claire Whitworth, Marjeta Urh, Chiara Maniaci, Alessio Ciulli, Satomi Imaide, Nicole Trainor, Andrea Testa, Vesna Vetma, Nancy Murphy, Kwok-Ho Chan, Danette L. Daniels, Scott J. Hughes
Bivalent small-molecule degraders, or proteolysis targeting chimeras (PROTACs), work by simultaneously binding a target protein and E3 ubiquitin ligase to produce a ternary complex. To drive target ubiquitination and degradation at low catalytic conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f76c01ffacb55b1f5c21e4c3fe9567
https://doi.org/10.26434/chemrxiv.13218695
https://doi.org/10.26434/chemrxiv.13218695
Autor:
Andrea Testa, Kwok-Ho Chan, R. Scott Lokey, Chad E. Townsend, Victoria G. Klein, Chiara Maniaci, Alessio Ciulli, Michael Zengerle, Scott J. Hughes
Publikováno v:
ACS Medicinal Chemistry Letters
Proteolysis targeting chimeras (PROTACs) are catalytic heterobifunctional molecules that can selectively degrade a protein of interest by recruiting a ubiquitin E3 ligase to the target, leading to its ubiquitylation and degradation by the proteasome.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2bbd70a4a73f831312ab59ea46182b
https://pubmed.ncbi.nlm.nih.gov/32939229
https://pubmed.ncbi.nlm.nih.gov/32939229
Autor:
Kwok Ho Chan, Ka Wai Terence Fung
Publikováno v:
Economics & Human Biology. 28:146-159
There are two competing views regarding the presence of social fathers on childrens’ cognitive ability: (1) either the social father provides more financial resources which benefit the children or (2) the mother with new partners may shift the focu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b7ed46078a6f98cf3bf906a3bf14dc3
https://doi.org/10.1016/j.ehb.2017.09.007
https://doi.org/10.1016/j.ehb.2017.09.007