Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Kwok Tai Lam"'
Autor:
Yan Han, Man To Ling, Huawei Mao, Jian Zheng, Ming Liu, Kwok Tai Lam, Yuan Liu, Wenwei Tu, Yu-Lung Lau
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86166 (2014)
Although smokers have increased susceptibility and severity of seasonal influenza virus infection, there is no report about the risk of 2009 pandemic H1N1 (pdmH1N1) or avian H9N2 (H9N2/G1) virus infection in smokers. In our study, we used mouse model
Externí odkaz:
https://doaj.org/article/319b147b38e3470f98ded3f53793190d
Autor:
Tim K. Tsang, Kwok-Tai Lam, Yinping Liu, Vicky J. Fang, Xiaofeng Mu, Nancy H. L. Leung, J. S. Malik Peiris, Gabriel M. Leung, Benjamin J. Cowling, Wenwei Tu
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background The protective effect of T cell-mediated immunity against influenza virus infections in natural settings remains unclear, especially in seasonal epidemics. Methods To explore the potential of such protection, we analyzed the blood
Externí odkaz:
https://doaj.org/article/ce7914eb109b444984597152877d9f03
Autor:
Aizhen Lv, Kwok-Tai Lam, Yu-Lung Lau, Jian Zheng, Huawei Mao, Yuan Liu, Liyan Wen, Zheng Xiang, Lei Huang, Yinping Liu, Wenwei Tu
Publikováno v:
Cellular & Molecular Immunology. 15:827-837
Natural killer (NK) cells are indispensable components of both the innate and adaptive immune response. However, their precise roles in the cross-talk between innate and adaptive immunity during influenza virus infection remain controversial. By comp
Autor:
Anderson Dik Wai Luk, Ke Ni, Yuet Wu, Kwok-Tai Lam, Koon-Wing Chan, Pamela P. Lee, Wenwei Tu, Huawei Mao, Yu Lung Lau
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology
Background X-linked agammaglobulinemia (XLA) is a primary immunodeficiency caused by Bruton’s tyrosine kinase (BTK) mutation. Patients are susceptible to severe enterovirus infections. The underlying mechanism remains unknown. BTK is involved in to
Autor:
Wenwei Tu, Kin-Hung Chow, Yi Guan, Kwok-Tai Lam, Pak-Leung Ho, Yu-Lung Lau, Yuet Wu, Joseph S. M. Peiris
Publikováno v:
Journal of Virology. 89:2013-2023
Secondary Streptococcus pneumoniae infection after influenza is a significant clinical complication resulting in morbidity and sometimes mortality. Prior influenza virus infection has been demonstrated to impair the macrophage and neutrophil response
Autor:
Yu Cho Woo, Bernard M.Y. Cheung, A. Z. L. Shih, Chi-Hang Lee, Carol H.Y. Fong, Kwok-Tai Lam, Edward D Janus, O. Y. Leung
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 9, p e0163424 (2016)
PLoS ONE, Vol 11, Iss 9, p e0163424 (2016)
BACKGROUND: The optimal reference range of homeostasis model assessment of insulin resistance (HOMA-IR) in normal Chinese population has not been clearly defined. Here we address this issue using the Hong Kong Cardiovascular Risk Factor Prevalence St
Publikováno v:
Journal of Clinical Immunology
Introduction Influenza virus is a potential cause of severe disease in the immunocompromised. X-linked agammaglobulinemia (XLA) is a primary immunodeficiency characterized by the lack of immunoglobulin, B cells, and plasma cells, secondary to mutatio
Autor:
J. S. Malik Peiris, Man To Ling, Wenwei Tu, Jing Guan, Helen K. W. Law, Ming Liu, Yan Han, Wai Po Chong, Kwok Tai Lam, Huawei Mao, Yu-Lung Lau, Kazue Takahashi
Publikováno v:
The Journal of Infectious Diseases
Background. Mannose-binding lectin (MBL) is a pattern-recognition molecule, which functions as a first line of host defense. Pandemic H1N1 (pdmH1N1) influenza A virus caused massive infection in 2009 and currently circulates worldwide. Avian influenz
Autor:
Kwok-Tai Lam, Wenwei Tu, Jian Zheng, Huawei Mao, Yu-Lung Lau, Yinping Liu, Ping-Lung Chan, J. S. Malik Peiris, Gang Qin
Publikováno v:
Journal of Virology. 84:4148-4157
Natural killer (NK) cells keep viral infections under control at the early phase by directly killing infected cells. Influenza is an acute contagious respiratory viral disease transmitted from host-to-host in the first few days of infection. The evas
Autor:
Ping-Lung Chan, Yu-Lung Lau, Jian Zheng, Huawei Mao, David B. Lewis, Gang Qin, Wenwei Tu, Yinping Liu, Kwok-Tai Lam
Publikováno v:
The Journal of Immunology. 183:3742-3750
Although recent studies have focused on CD4+ regulatory T cells (Treg), CD8+ Treg have also been reported to play important roles in the induction and maintenance of immune tolerance. Adoptive transfer of CD8+ Treg in rodents or induction of CD8+ Tre