Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Kwok Tai Lam"'
Autor:
Tim K. Tsang, Kwok-Tai Lam, Yinping Liu, Vicky J. Fang, Xiaofeng Mu, Nancy H. L. Leung, J. S. Malik Peiris, Gabriel M. Leung, Benjamin J. Cowling, Wenwei Tu
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background The protective effect of T cell-mediated immunity against influenza virus infections in natural settings remains unclear, especially in seasonal epidemics. Methods To explore the potential of such protection, we analyzed the blood
Externí odkaz:
https://doaj.org/article/ce7914eb109b444984597152877d9f03
Autor:
Anderson Dik Wai Luk, Ke Ni, Yuet Wu, Kwok-Tai Lam, Koon-Wing Chan, Pamela P. Lee, Wenwei Tu, Huawei Mao, Yu Lung Lau
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
BackgroundX-linked agammaglobulinemia (XLA) is a primary immunodeficiency caused by Bruton’s tyrosine kinase (BTK) mutation. Patients are susceptible to severe enterovirus infections. The underlying mechanism remains unknown. BTK is involved in tol
Externí odkaz:
https://doaj.org/article/b72455d63f3a4cb9a73a151fd3f1bcd3
Autor:
Jian Zheng, Wai-Lan Wu, Yinping Liu, Zheng Xiang, Ming Liu, Kwok-Hung Chan, Siu-Ying Lau, Kwok-Tai Lam, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Lanjuan Li, Honglin Chen, Yu-Lung Lau, Kwok-Yung Yuen, Wenwei Tu
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135999 (2015)
A novel avian influenza virus H7N9 infection occurred among human populations since 2013. Although the lack of sustained human-to-human transmission limited the epidemics caused by H7N9, the late presentation of most patients and the emergence of neu
Externí odkaz:
https://doaj.org/article/7736a1208650482690917aaa0548e2bf
Autor:
Yan Han, Man To Ling, Huawei Mao, Jian Zheng, Ming Liu, Kwok Tai Lam, Yuan Liu, Wenwei Tu, Yu-Lung Lau
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86166 (2014)
Although smokers have increased susceptibility and severity of seasonal influenza virus infection, there is no report about the risk of 2009 pandemic H1N1 (pdmH1N1) or avian H9N2 (H9N2/G1) virus infection in smokers. In our study, we used mouse model
Externí odkaz:
https://doaj.org/article/319b147b38e3470f98ded3f53793190d
Autor:
Jian Zheng, Ping-Lung Chan, Yinping Liu, Gang Qin, Zheng Xiang, Kwok-Tai Lam, David B Lewis, Yu-Lung Lau, Wenwei Tu
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82203 (2013)
Inducible co-stimulator (ICOS) is a member of CD28/Cytotoxic T-lymphocyte Antigen-4 (CTLA-4) family and broadly expressed in activated CD4(+) T cells and induced regulatory CD4(+) T cells (CD4(+) iTreg). ICOS-related signal pathway could be activated
Externí odkaz:
https://doaj.org/article/d5a07ebec4bb43ab83cc6b9794d479ec
Autor:
Ping-Lung Chan, Jian Zheng, Yinping Liu, Kwok-Tai Lam, Zheng Xiang, Huawei Mao, Yuan Liu, Gang Qin, Yu-Lung Lau, Wenwei Tu
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67969 (2013)
Although diverse functions of different toll-like receptors (TLR) on human natural regulatory T cells have been demonstrated recently, the role of TLR-related signals on human induced regulatory T cells remain elusive. Previously our group developed
Externí odkaz:
https://doaj.org/article/490b4044495847998e52072ec08e15a8
Autor:
Aizhen Lv, Kwok-Tai Lam, Yu-Lung Lau, Jian Zheng, Huawei Mao, Yuan Liu, Liyan Wen, Zheng Xiang, Lei Huang, Yinping Liu, Wenwei Tu
Publikováno v:
Cellular & Molecular Immunology. 15:827-837
Natural killer (NK) cells are indispensable components of both the innate and adaptive immune response. However, their precise roles in the cross-talk between innate and adaptive immunity during influenza virus infection remain controversial. By comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82909a9b6180cd9442db2e34fe40a99
https://doi.org/10.1038/cmi.2017.10
https://doi.org/10.1038/cmi.2017.10
Autor:
Wenwei Tu, Kin-Hung Chow, Yi Guan, Kwok-Tai Lam, Pak-Leung Ho, Yu-Lung Lau, Yuet Wu, Joseph S. M. Peiris
Publikováno v:
Journal of Virology. 89:2013-2023
Secondary Streptococcus pneumoniae infection after influenza is a significant clinical complication resulting in morbidity and sometimes mortality. Prior influenza virus infection has been demonstrated to impair the macrophage and neutrophil response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c785e0b60425ec3ed09ceea4bd8246
https://doi.org/10.1128/jvi.02455-14
https://doi.org/10.1128/jvi.02455-14
Autor:
Yu Cho Woo, Bernard M.Y. Cheung, A. Z. L. Shih, Chi-Hang Lee, Carol H.Y. Fong, Kwok-Tai Lam, Edward D Janus, O. Y. Leung
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 9, p e0163424 (2016)
PLoS ONE, Vol 11, Iss 9, p e0163424 (2016)
BACKGROUND: The optimal reference range of homeostasis model assessment of insulin resistance (HOMA-IR) in normal Chinese population has not been clearly defined. Here we address this issue using the Hong Kong Cardiovascular Risk Factor Prevalence St
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb0afa1da7b01b13f74fcef11832cca
https://pubmed.ncbi.nlm.nih.gov/27658115
https://pubmed.ncbi.nlm.nih.gov/27658115
Publikováno v:
Journal of Clinical Immunology
Introduction Influenza virus is a potential cause of severe disease in the immunocompromised. X-linked agammaglobulinemia (XLA) is a primary immunodeficiency characterized by the lack of immunoglobulin, B cells, and plasma cells, secondary to mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a66dd268948f65dbc24feab360aa682e
https://doi.org/10.1007/s10875-011-9639-y
https://doi.org/10.1007/s10875-011-9639-y