Neuroendocrine lineage commitment of small cell lung cancers can be leveraged into p53-independent non-cytotoxic therapy

Autor: Sudipta Biswas, Kai Kang, Kwok Peng Ng, Tomas Radivoyevitch, Kurt Schalper, Hua Zhang, Daniel J. Lindner, Anish Thomas, David MacPherson, Brian Gastman, David S. Schrump, Kwok-Kin Wong, Vamsidhar Velcheti, Yogen Saunthararajah

Publikováno v: Cell Reports, Vol 42, Iss 8, Pp 113016- (2023)

Summary: Small cell lung cancers (SCLCs) rapidly resist cytotoxic chemotherapy and immune checkpoint inhibitor (ICI) treatments. New, non-cross-resistant therapies are thus needed. SCLC cells are committed into neuroendocrine lineage then maturation

Externí odkaz: https://doaj.org/article/6e798291ce2a49cb8119368cddc4ce46

The use of methylene blue in adult patients with septic shock: a systematic review and meta-analysis.

Autor: Ng KT; University of Malaya, Department of Anesthesiology, Kuala Lumpur, Malaysia., Kwok PE; Quinnipiac University Frank H. Netter School of Medicine, Waterbury Hospital, Department of Surgery, North Haven, United States., Lim WE; University of Glasgow, Department of Anesthesiology, Glasgow, United Kingdom., Teoh WY; University of Liverpool, Department of Anesthesiology, Liverpool, United Kingdom., Hasan MS; University of Malaya, Department of Anesthesiology, Kuala Lumpur, Malaysia., Abidin MFZ; University of Malaya, Department of Anesthesiology, Kuala Lumpur, Malaysia. Electronic address: mohdfitry@um.edu.my.

Publikováno v: Brazilian journal of anesthesiology (Elsevier) [Braz J Anesthesiol] 2024 Nov 28, pp. 844580. Date of Electronic Publication: 2024 Nov 28.

Incidence and management of pleural effusions in patients with Wilms tumor: A Pediatric Surgical Oncology Research Collaborative study.

Autor: Al-Hadidi A; Department of Surgery, Division of Pediatric Surgery, The Ohio State University College of Medicine, Nationwide Children's Hospital, Columbus, Ohio, USA., Rinehardt HN; Division of Pediatric General and Thoracic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Sutthatarn P; Department of Surgery, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Talbot LJ; Department of Surgery, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Murphy AJ; Department of Surgery, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Whitlock R; Division of Pediatric Surgery, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA., Condon S; Division of Pediatric Surgery, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA., Naik-Mathuria B; Division of Pediatric Surgery, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA., Utria AF; Seattle Children's Hospital, University of Washington, Seattle, Washington, USA., Rothstein DH; Seattle Children's Hospital, University of Washington, Seattle, Washington, USA., Chen SY; Division of Pediatric Surgery, Department of Surgery, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Wong-Michalak S; Division of Pediatric Surgery, Department of Surgery, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Kim ES; Division of Pediatric Surgery, Department of Surgery, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Short SS; Primary Children's Hospital, University of Utah, Salt Lake City, Utah, USA., Meyers RL; Primary Children's Hospital, University of Utah, Salt Lake City, Utah, USA., Kastenberg ZJ; Primary Children's Hospital, University of Utah, Salt Lake City, Utah, USA., Johnston ME 2nd; Division of Pediatric General and Thoracic Surgery Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, USA., Zens T; Division of Pediatric General and Thoracic Surgery Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, USA., Dasgupta R; Division of Pediatric General and Thoracic Surgery Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, USA., Malek MM; Division of Pediatric General and Thoracic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Calabro K; Centre Hospitalier Universitaire Ste-Justine, Université de Montréal, Montréal, Quebec, Canada., Piché N; Centre Hospitalier Universitaire Ste-Justine, Université de Montréal, Montréal, Quebec, Canada., Callas H; Ann & Robert H Lurie Children's Hospital of Chicago, Northwestern University, Chicago, Illinois, USA., Lautz TB; Ann & Robert H Lurie Children's Hospital of Chicago, Northwestern University, Chicago, Illinois, USA., McKay K; Department of Pediatric Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Lovvorn HN 3rd; Department of Pediatric Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Commander SJ; Department of Surgery, Division of Pediatric Surgery, Duke University Medical Center, Durham, North Carolina, USA., Tracy ET; Department of Surgery, Division of Pediatric Surgery, Duke University Medical Center, Durham, North Carolina, USA., Lund SB; Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA., Polites SF; Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA., Davidson J; Department of Surgery, Division of Paediatric Surgery, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada., Dhooma J; Department of Surgery, Division of Paediatric Surgery, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada., Seemann NM; Department of Surgery, Division of Paediatric Surgery, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada., Marquart JP; Division of Pediatric Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Gainer H; Division of Pediatric Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Lal DR; Division of Pediatric Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Rich BS; Division of Pediatric Surgery, Cohen Children's Medical Center, Northwell Health, New Hyde Park, New York, USA., Glick RD; Division of Pediatric Surgery, Cohen Children's Medical Center, Northwell Health, New Hyde Park, New York, USA., Maloney L; Department of Surgery, Division of Pediatric Surgery, Oregon Health and Science University, Portland, Oregon, USA., Radu S; Department of Surgery, Division of Pediatric Surgery, Oregon Health and Science University, Portland, Oregon, USA., Fialkowski EA; Department of Surgery, Division of Pediatric Surgery, Oregon Health and Science University, Portland, Oregon, USA., Kwok PE; Departments of Surgery and Urology, IWK Health, Dalhousie University, Halifax, Nova Scotia, Canada., Romao RLP; Departments of Surgery and Urology, IWK Health, Dalhousie University, Halifax, Nova Scotia, Canada., Rubalcava N; University of Michigan Section of Pediatric Surgery, Ann Arbor, Michigan, USA., Ehrlich PF; University of Michigan Section of Pediatric Surgery, Ann Arbor, Michigan, USA., Newman E; University of Michigan Section of Pediatric Surgery, Ann Arbor, Michigan, USA., Diehl T; American Family Children's Hospital, University of Wisconsin-Madison, Madison, Wisconsin, USA., Le HD; American Family Children's Hospital, University of Wisconsin-Madison, Madison, Wisconsin, USA., Polcz V; Division of Pediatric Surgery, University of Florida, Gainesville, Florida, USA., Petroze RT; Division of Pediatric Surgery, University of Florida, Gainesville, Florida, USA., Stanek J; Department of Surgery, Division of Pediatric Surgery, The Ohio State University College of Medicine, Nationwide Children's Hospital, Columbus, Ohio, USA., Aldrink JH; Department of Surgery, Division of Pediatric Surgery, The Ohio State University College of Medicine, Nationwide Children's Hospital, Columbus, Ohio, USA.

Publikováno v: International journal of cancer [Int J Cancer] 2022 Nov 15; Vol. 151 (10), pp. 1696-1702. Date of Electronic Publication: 2022 Jul 14.

The effect of intravenous magnesium on postoperative morphine consumption in noncardiac surgery: A systematic review and meta-analysis with trial sequential analysis.

Autor: Ng KT; From the Department of Anaesthesiology, University of Malaya (KTN), Department of Medicine, International Medical University, Kuala Lumpur, Malaysia (JLLY, INI, PEK), Department of Medicine, University of Liverpool, Liverpool, UK (WYT) and Department of Dental Health, International Medical University, Kuala Lumpur, Malaysia (WJK)., Yap JLL, Izham IN, Teoh WY, Kwok PE, Koh WJ

Publikováno v: European journal of anaesthesiology [Eur J Anaesthesiol] 2020 Mar; Vol. 37 (3), pp. 212-223.