Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kwok Lim Lam"'
Autor:
Ronald Ching Wan Ma, Heung Man Lee, Vincent Kwok Lim Lam, Claudia Ha Ting Tam, Janice Siu Ka Ho, Hai-Lu Zhao, Jing Guan, Alice Pik Shan Kong, Eric Lau, Guozhi Zhang, Andrea Luk, Ying Wang, Stephen Kwok Wing Tsui, Ting Fung Chan, Cheng Hu, Wei Ping Jia, Kyong Soo Park, Hong Kyu Lee, Hiroto Furuta, Kishio Nanjo, E Shyong Tai, Daniel Peng-Keat Ng, Nelson Leung Sang Tang, Jean Woo, Ping Chung Leung, Hong Xue, Jeffrey Wong, Po Sing Leung, Terrence C K Lau, Peter Chun Yip Tong, Gang Xu, Maggie Chor Yin Ng, Wing Yee So, Juliana Chung Ngor Chan
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84770 (2014)
In Asia, young-onset type 2 diabetes (YOD) is characterized by obesity and increased risk for cardiovascular disease (CVD). In a genome-wide association study (GWAS) of 99 Chinese obese subjects with familial YOD diagnosed before 40-year-old and 101
Externí odkaz:
https://doaj.org/article/11e23d52cb9249cfa1e5b8595c2f459a
Autor:
Vincent Kwok Lim Lam, Ronald Ching Wan Ma, Heung Man Lee, Cheng Hu, Kyong Soo Park, Hiroto Furuta, Ying Wang, Claudia Ha Ting Tam, Xueling Sim, Daniel Peng-Keat Ng, Jianjun Liu, Tien-Yin Wong, E Shyong Tai, Andrew P Morris, DIAGRAM Consortium, Nelson Leung Sang Tang, Jean Woo, Ping Chung Leung, Alice Pik Shan Kong, Risa Ozaki, Wei Ping Jia, Hong Kyu Lee, Kishio Nanjo, Gang Xu, Maggie Chor Yin Ng, Wing-Yee So, Juliana Chung Ngor Chan
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e62378 (2013)
Type 2 diabetes (T2D) is a complex disease characterized by beta cell dysfunctions. Islet amyloid polypeptide (IAPP) is highly conserved and co-secreted with insulin with over 40% of autopsy cases of T2D showing islet amyloid formation due to IAPP ag
Externí odkaz:
https://doaj.org/article/44faff5d4da8477cb7505074b00fd44b
Publikováno v:
Biomaterials. 274
Cells can sense mechanical signals through cytoskeleton reorganization. We previously discovered the formation of omni-directional actin protrusions upon compression loading, namely compression-induced actin protrusions (CAPs), in human mesenchymal s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef728c7aac78a727456b0e7f8d2e4d03
https://pubmed.ncbi.nlm.nih.gov/33933985
https://pubmed.ncbi.nlm.nih.gov/33933985
Autor:
Claudia Ha Ting Tam, Janice Sin Ka Ho, Ying Wang, Heung Man Lee, Vincent Kwok Lim Lam, Soren Germer, Mitchell Martin, Wing Yee So, Ronald Ching Wan Ma, Juliana Chung Ngor Chan, Maggie Chor Yin Ng
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11428 (2010)
BackgroundPrevious studies identified melatonin receptor 1B (MTNR1B), islet-specific glucose 6 phosphatase catalytic subunit-related protein (G6PC2), glucokinase (GCK) and glucokinase regulatory protein (GCKR) as candidate genes for type 2 diabetes (
Externí odkaz:
https://doaj.org/article/b9fae586310a4eb090493d47f4a01baf
Publikováno v:
In BBA - Gene Structure and Expression 2005 1731(3):191-201
Publikováno v:
Biomaterials. 258:120292
Mechanical signal is important for regulating stem cell fate, but the molecular mechanisms involved are unclear. Cell-matrix adhesions are important molecular mechanosensors that their formation and maturation are force-dependent processes. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e1c2d3bce6dc915c54e6cb9ba17953
https://doi.org/10.1016/j.biomaterials.2020.120292
https://doi.org/10.1016/j.biomaterials.2020.120292
Publikováno v:
Biomaterials. 213:119210
Mesenchymal condensation is a critical transitional stage that precedes cartilage or bone formation. A microencapsulation technique was previously established to entrap mesenchymal stem cells (MSC) in nanofibrous collagen meshwork. We hypothesize tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323e869b3f84fd882b0f493a5c5ade5e
https://doi.org/10.1016/j.biomaterials.2019.05.021
https://doi.org/10.1016/j.biomaterials.2019.05.021
Autor:
Kwok Lim Lam, Lok Yee Chow, Yun Kowk Wing, Merce Garcia-Barcelo, Helen F.K. Chiu, Dominic T.S. Lee, Mary M.Y. Waye
Publikováno v:
Clinical Chemistry. 46:18-23
Background: The cytochrome P450 CYP2D6 enzyme debrisoquine 4-hydroxylase metabolizes many different classes of commonly used drugs, such as tricyclic antidepressants and neuroleptics. Genetic polymorphism of the CYP2D6 gene is responsible for pronoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e7651dec1d46ae18f06a6a2f83dc806
https://doi.org/10.1093/clinchem/46.1.18
https://doi.org/10.1093/clinchem/46.1.18
Publikováno v:
Marine Environmental Research. 46:597-600
We determined metal concentrations in tissues of tilapia (Tilapia mossambica) collected from Shing Mun River. Two sites (Tai Wai and Fo Tan) were chosen for our investigation, and the metal concentrations were higher in liver than in muscle and gills
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65c89c1fa953bef6f2f99c456ecae525
https://doi.org/10.1016/s0141-1136(98)00012-9
https://doi.org/10.1016/s0141-1136(98)00012-9
Autor:
Carmen K.M. Shiu, Judy Ka-Yee Wong, Kwok Lim Lam, Pat Chun Chan, Felice W.-Y. Wong, King Ming Chan
Publikováno v:
Biochimica et biophysica acta. 1676(2)
Metallothionein-1 (MT-1) cDNA clones were isolated from a common carp (Cyprinus carpio) uninduced hepatopancreas cDNA library. Northern blot assay using the common carp (cc) MT-1 cDNA as a probe showed high fold induction of ccMT mRNA levels in the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::325d73473e7119cea766040a7c04cd28
https://pubmed.ncbi.nlm.nih.gov/14746911
https://pubmed.ncbi.nlm.nih.gov/14746911