Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Kwok Ho Yip"'
Autor:
Kwok Ho Yip, Natasha Kolesnikoff, Nicholas Hauschild, Lisa Biggs, Angel F. Lopez, Stephen J. Galli, Sharad Kumar, Michele A. Grimbaldeston
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Aberrant activation of the IgE receptor on mast cells leads to allergic responses. Here, the authors identify an E3 ligase and adaptor protein that can reduce IgE signalling by targeting phosphorylated-Syk for degradation.
Externí odkaz:
https://doaj.org/article/1de87b299b0044dc8a38c75fa107c015
Autor:
Yangyang Yu, Kwok Ho Yip, Issan Yee San Tam, Sze Wing Sam, Chun Wai Ng, Wei Zhang, Hang Yung Alaster Lau
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112989 (2014)
Mast cells are pivotal in the pathogenesis of allergy and inflammation. In addition to the classical IgE-dependent mechanism involving crosslinking of the high-affinity receptor for IgE (FcεRI), mast cells are also activated by Toll-like receptors (
Externí odkaz:
https://doaj.org/article/20b2790c1e504b70a70d16c0e42ffaf2
Publikováno v:
Biochemistry and Biophysics Reports, Vol 31, Iss , Pp 101305- (2022)
Our laboratory focuses on the development of novel neuroprotective cationic peptides, such poly-arginine-18 (R18: 18-mer of l-arginine; net charge +18) and its d-enantiomer R18D in stroke and other brain injuries. In the clinical development of R18/R
Externí odkaz:
https://doaj.org/article/28aecd922d6f4b9ab7fa148358ae958f
Autor:
Kwok Ho Yip, Jessica Chao, Carl Coolen, Harshita Pant, Anita Kral, William Smith, Quenten Schwarz, Michele A. Grimbaldeston, Stuart Pitson, Angel F. Lopez, Joanna Woodcock, Damon J. Tumes
Publikováno v:
Journal of Allergy and Clinical Immunology.
Refereed/Peer-reviewed Background: Mast cells (MCs) are tissue-resident immune cells that mediate IgE-dependent allergic responses. Downstream of FcεRI, an intricate network of receptor-specific signaling pathways and adaptor proteins govern MC func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d24154cf629db04d3d0edd42cc71a27
https://doi.org/10.1016/j.jaci.2023.04.011
https://doi.org/10.1016/j.jaci.2023.04.011
Autor:
Harshita Pant, Timothy R. Hercus, Damon J. Tumes, Kwok Ho Yip, Michael W. Parker, Catherine M. Owczarek, Angel F. Lopez, David P. Huston
Publikováno v:
The Journal of allergy and clinical immunology.
The family of cytokines that comprises IL-3, IL-5, and GM-CSF was discovered over 30 years ago, and their biological activities and resulting impact in clinical medicine has continued to expand ever since. Originally identified as bone marrow growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4b58fc3bdf01c394b0e56b2ade99e8
https://pubmed.ncbi.nlm.nih.gov/36424209
https://pubmed.ncbi.nlm.nih.gov/36424209
Autor:
Gino Vairo, Nicholas J. Wilson, Hayley S. Ramshaw, Timo Kraushaar, Barbara J. McClure, Timothy R. Hercus, Mhairi Maxwell, Elmar Raquet, Damon J. Tumes, Duncan R. McKenzie, Kathleen Zeglinski, Harshita Pant, Michele A. Grimbaldeston, Catherine M. Owczarek, Joachim Röder, Angel F. Lopez, Jessica Chao, Kwok Ho Yip, Katherine Monaghan, Monther Alhamdoosh, Jia Hong Fong, Andrew Hammet
Allergic contact dermatitis (ACD) is a prevalent and poorly controlled inflammatory disease caused by skin infiltration of T cells and granulocytes. The beta common (βc) cytokines GM-CSF, IL-3, and IL-5 are powerful regulators of granulocyte functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66938273824c0ce03c6325a3d71da595
https://hdl.handle.net/11541.2/28703
https://hdl.handle.net/11541.2/28703
Autor:
Gino Vairo, Naomi Woodman, Kwok Ho Yip, Christopher Brown, Catherine M. Owczarek, Harshita Pant, Michael J. Wilson, Mark Schembri, Damon J. Tumes, Monther Alhamdoosh, Nicholas J. Wilson, Andrew D. Nash, Michele A. Grimbaldeston, Milica Ng, Samantha J. Busfield, Angel F. Lopez
Publikováno v:
Allergy. 75:475-478
Refereed/Peer-reviewed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6287d481489c30fe71fc8835e611b489
https://doi.org/10.1111/all.14041
https://doi.org/10.1111/all.14041
Autor:
Kwok Ho Yip, Angus H Sarah, Harshita Pant, Angel F. Lopez, Damon J. Tumes, Jessica Chao, Gökhan Cildir, Mark A Schembri, April P De Silva
Publikováno v:
The Laryngoscope. 131
Objectives/Hypothesis: The efficacy of short-term oral corticosteroids in chronic rhinosinusitis without nasal polyps (CRSsNP) is unknown. The aim of this controlled study was to assess the immediate and long-term outcomes from a short course of a co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45eeffbd345e043ff36e70ab0eeb256
https://doi.org/10.1002/lary.29495
https://doi.org/10.1002/lary.29495
Autor:
Kwok Ho, Yip, Duncan, McKenzie, Hayley S, Ramshaw, Jessica, Chao, Barbara J, McClure, Elmar, Raquet, Timo, Kraushaar, Joachim, Röder, Mhairi, Maxwell, Monther, Alhamdoosh, Andrew, Hammet, Jia Hong, Fong, Kathleen, Zeglinski, Katherine, Monaghan, Harshita, Pant, Michele A, Grimbaldeston, Gino, Vairo, Nicholas J, Wilson, Catherine M, Owczarek, Timothy R, Hercus, Angel F, Lopez, Damon J, Tumes
Publikováno v:
The Journal of investigative dermatology. 142(4)
Allergic contact dermatitis (ACD) is a prevalent and poorly controlled inflammatory disease caused by skin infiltration of T cells and granulocytes. The beta common (β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f25b1fa05bdf0b338e4a02a45253d761
https://pubmed.ncbi.nlm.nih.gov/34537191
https://pubmed.ncbi.nlm.nih.gov/34537191
Mast cells (MC)s are evolutionarily conserved, tissue-resident immune cells with diverse roles in allergy, cancer, and protection from infection by helminths and microorganisms. The significant diversity in MC development and tissue-specific function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2a9eab820af9b80f034f6500c3d0c3
https://hdl.handle.net/11541.2/148105
https://hdl.handle.net/11541.2/148105