Gliomatosis cerebri in children: A poor prognostic phenotype of diffuse gliomas with a distinct molecular profile.

Autor: Nussbaumer G; Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria., Benesch M; Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria., Grabovska Y; Division of Molecular Pathology, Institute of Cancer Research, London, UK., Mackay A; Division of Molecular Pathology, Institute of Cancer Research, London, UK., Castel D; U981, Molecular Predictors and New Targets in Oncology, Team Genomics and Oncogenesis of Pediatric Brain Tumors, INSERM, Gustave Roussy, Université Paris-Saclay, Villejuif, France.; Department of Pediatric and Adolescent Oncology, Gustave Roussy, Université Paris-Saclay, Villejuif, France., Grill J; U981, Molecular Predictors and New Targets in Oncology, Team Genomics and Oncogenesis of Pediatric Brain Tumors, INSERM, Gustave Roussy, Université Paris-Saclay, Villejuif, France.; Department of Pediatric and Adolescent Oncology, Gustave Roussy, Université Paris-Saclay, Villejuif, France., Alonso MM; Department of Pediatrics, Clínica Universidad de Navarra, Pamplona, Spain.; Solid Tumor Program, Center for the Applied Medical Research, Pamplona, Navarra, Spain.; Health Research Institute of Navarra (IdiSNA), Pamplona, Navarra, Spain., Antonelli M; Department of Radiological, Oncological and Anatomo-Pathological Sciences, Sapienza University, Rome, Italy., Bailey S; Department of Paediatric Oncology, Sir James Spence Institute of Child Health, Royal Victoria Infirmary Queen Victoria Road, Newcastle upon Tyne, UK., Baugh JN; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Biassoni V; Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Blattner-Johnson M; Division of Pediatric Glioma Research, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany., Broniscer A; Division of Hematology-Oncology, Children's Hospital of Pittsburgh, Pittsburgh, PA, U.S.A., Carai A; Neurosurgery Unit, Bambino Gesù Children's Hospital (IRCCS), Rome, Italy., Colafati GS; Oncological Neuroradiology and Advanced Diagnostics Unit, Bambino Gesù Children's Hospital (IRCCS), Rome, Italy., Colditz N; Division of Pediatric Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany., Corbacioglu S; Department of Pediatric Hematology, Oncology and Stem Cell Transplantation, University of Regensburg, Regensburg, Germany., Crampsie S; Division of Molecular Pathology, Institute of Cancer Research, London, UK., Entz-Werle N; UMR CNRS 7021-Laboratory of Bioimagery and Pathologies Team tumor signaling and therapeutic targets, University of Strasbourg, Illkirch, France.; Pediatric Onco-Hematology Department-Pediatrics III, University Hospital of Strasbourg, Strasbourg, France., Eyrich M; Pediatric Hematology and Oncology, Department of Pediatrics, University Hospital Würzburg, Würzburg, Germany., Friker LL; Institute of Neuropathology, DGNN Brain Tumor Reference Center, University of Bonn Medical Center, Bonn, Germany., Frühwald MC; Pediatric and Adolescent Medicine, Swabian Children's Cancer Center, University Medical Center Augsburg, Augsburg, Germany., Garrè ML; Neuro-Oncology Unit, IRCSS Istituto Giannina Gaslini, Genoa, Italy., Gerber NU; Department of Oncology and Children's Research Centre, University Children's Hospital, Zurich, Switzerland., Giangaspero F; Department of Radiological, Oncological and Anatomo-Pathological Sciences, Sapienza University, Rome, Italy., Gil-da-Costa MJ; Pediatric Oncology Department, University Hospital São João, Porto, Portugal., Graf N; Department of Pediatric Oncology and Hematology, Saarland University, Homburg, Germany., Hargrave D; Pediatric Oncology, Great Ormond Street Hospital for Children, London, UK., Hauser P; Second Department of Pediatrics, Semmelweis University, Budapest, Hungary., Herrlinger U; Division of Clinical Neuro-Oncology, Department of Neurology, University Hospital Bonn, Bonn, Germany., Hoffmann M; Division of Pediatric Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany., Hulleman E; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Izquierdo E; Division of Molecular Pathology, Institute of Cancer Research, London, UK., Jacobs S; Department of Pediatric Hematology and Oncology, University Hospitals Leuven, Belgium.; Pediatric Oncology, Department of Oncology, KU Leuven, Belgium., Karremann M; Department of Pediatric and Adolescent Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Kattamis A; Division of Pediatric Hematology-Oncology, First Department of Pediatrics, National and Kapodistrian University of Athens, 'Aghia Sophia' Children's Hospital, Athens, Greece., Kebudi R; Division of Pediatric Hematology-Oncology, Institute of Oncology, Istanbul University, Istanbul, Turkey., Kortmann RD; Department of Radiation Oncology, University of Leipzig, Leipzig, Germany., Kwiecien R; Institute of Biostatistics and Clinical Research, University of Münster, Münster, Germany., Massimino M; Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Mastronuzzi A; Department of Onco-Hematology, Gene and Cell Therapy, Bambino Gesù Children's Hospital (IRCCS), Rome, Italy., Miele E; Department of Onco-Hematology, Gene and Cell Therapy, Bambino Gesù Children's Hospital (IRCCS), Rome, Italy., Morana G; Department of Neurosciences, University of Turin, Turin, Italy., Noack CM; Center of Radiology, Department of Diagnostic and Interventional Radiology and Neuroradiology, Hospital of Fulda, Fulda, Germany., Pentikainen V; Division of Hematology-Oncology and Stem Cell Transplantation, Children's Hospital, Helsinki University Hospital, Helsinki, Finland., Perwein T; Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria., Pfister SM; National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg, Germany.; Department of Pediatric Oncology, Hematology & Immunology, Heidelberg University Hospital, Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany., Pietsch T; Institute of Neuropathology, DGNN Brain Tumor Reference Center, University of Bonn Medical Center, Bonn, Germany., Roka K; Division of Pediatric Hematology-Oncology, First Department of Pediatrics, National and Kapodistrian University of Athens, 'Aghia Sophia' Children's Hospital, Athens, Greece., Rossi S; Pathology Unit, Bambino Gesù Children's Hospital (IRCCS), Rome, Italy., Rutkowski S; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Schiavello E; Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy., Seidel C; Department of Radiation Oncology, University of Leipzig, Leipzig, Germany., Štěrba J; Department of Pediatric Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic., Sturm D; Department of Pediatric Oncology, Hematology & Immunology, Heidelberg University Hospital, Heidelberg, Germany.; Division of Pediatric Glioma Research, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany., Sumerauer D; Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague, Czech Republic., Tacke A; Division of Pediatric Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany., Temelso S; Division of Molecular Pathology, Institute of Cancer Research, London, UK., Valentini C; Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany., van Vuurden D; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Varlet P; GHU-Paris Psychiatry and Neuroscience, Sainte-Anne Hospital, Department of Neuropathology, Paris, France., Veldhuijzen van Zanten SEM; Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Vinci M; Department of Onco-Hematology, Gene and Cell Therapy, Bambino Gesù Children's Hospital (IRCCS), Rome, Italy., von Bueren AO; Department of Pediatrics, Obstetrics and Gynecology, Division of Pediatric Hematology and Oncology, University Hospital Geneva, Geneva, Switzerland., Warmuth-Metz M; Institute of Diagnostic and Interventional Neuroradiology, University of Würzburg, Würzburg, Germany., Wesseling P; Department of Pathology, Amsterdam UMC, Amsterdam, The Netherlands.; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Wiese M; Neurosurgery Unit, Bambino Gesù Children's Hospital (IRCCS), Rome, Italy., Wolff JEA; AbbVie Inc, Oncology Development, North Chicago, IL, U.S.A., Zamecnik J; Department of Pathology and Molecular Medicine, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague, Czech Republic., Morales La Madrid A; Pediatric Neuro-Oncology, Pediatric Cancer Center Barcelona, Hospital Sant Joan de Deu, Barcelona, Spain., Bison B; Neuroradiological Reference Center for the Pediatric Brain Tumor (HIT) Studies of the German Society of Pediatric Oncology and Hematology, University Augsburg, Faculty of Medicine, Germany.; Diagnostic and Interventional Neuroradiology, Faculty of Medicine, University of Augsburg, Augsburg, Germany., Gielen GH; Institute of Neuropathology, DGNN Brain Tumor Reference Center, University of Bonn Medical Center, Bonn, Germany., Jones DTW; Division of Pediatric Glioma Research, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany., Jones C; Division of Molecular Pathology, Institute of Cancer Research, London, UK., Kramm CM; Division of Pediatric Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany.

Publikováno v: Neuro-oncology [Neuro Oncol] 2024 Sep 05; Vol. 26 (9), pp. 1723-1737.

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Pediatric high-grade gliomas and the WHO CNS Tumor Classification-Perspectives of pediatric neuro-oncologists and neuropathologists in light of recent updates.

Autor: Gielen GH; Institute of Neuropathology, Medical Center Bonn, Bonn, Germany., Baugh JN; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., van Vuurden DG; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Veldhuijzen van Zanten SEM; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Hargrave D; Great Ormond Street Hospital for Children, NHS Trust, London, UK., Massimino M; Fondazione Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale dei Tumori, Milan, Italy., Biassoni V; Fondazione Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale dei Tumori, Milan, Italy., Morales la Madrid A; Pediatric Neuro-Oncology, Department of Pediatric Oncology, Hospital Sant Joan de Deu, Passeig Sant Joan de Déu 2, Barcelona, Spain., Karremann M; Department of Pediatric and Adolescent Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Wiese M; Division of Pediatric Hematology and Oncology , University Medical Center Goettingen, Goettingen, Germany., Thomale U; Pediatric Neurosurgery, Charité Universitätsmedizin Berlin, Berlin, Germany., Janssens GO; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., von Bueren AO; Division of Pediatric Oncology and Hematology, Department of Women, Child and Adolescent, University Hospital of Geneva, Geneva, Switzerland., Perwein T; Division of Pediatric Hemato-Oncology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria., Nussbaumer G; Division of Pediatric Hemato-Oncology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria., Hoving EW; Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Niehusmann P; Department of Neuropathology, Oslo University Hospital, Oslo, Norway., Gessi M; Department of Pathology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Kwiecien R; Institute of Biostatistics and Clinical Research, Faculty of Medicine, University of Münster, Münster, Germany., Bailey S; Sir James Spence Institute of Child Health, Royal Victoria Infirmary, Newcastle upon Tyne, UK., Pietsch T; Institute of Neuropathology, Medical Center Bonn, Bonn, Germany., Andreiuolo F; Institute of Neuropathology, Medical Center Bonn, Bonn, Germany., Kramm CM; Division of Pediatric Hematology and Oncology , University Medical Center Goettingen, Goettingen, Germany.

Publikováno v: Neuro-oncology advances [Neurooncol Adv] 2022 May 20; Vol. 4 (1), pp. vdac077. Date of Electronic Publication: 2022 May 20 (Print Publication: 2022).

Refining M1 stage in medulloblastoma: criteria for cerebrospinal fluid cytology and implications for improved risk stratification from the HIT-2000 trial.

Autor: Hagel C; Institute of Neuropathology, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany. Electronic address: hagel@uke.de., Sloman V; Department of Pediatric Hematology and Oncology, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany., Mynarek M; Department of Pediatric Hematology and Oncology, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany., Petrasch K; Department of Pediatric Hematology and Oncology, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany., Obrecht D; Department of Pediatric Hematology and Oncology, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany., Kühl J; Department of Pediatric Hematology and Oncology, University Children's Hospital Wuerzburg, Germany., Deinlein F; Department of Pediatric Hematology and Oncology, University Children's Hospital Wuerzburg, Germany., Schmid R; Department of Pediatric Hematology and Oncology, University Children's Hospital Wuerzburg, Germany., von Bueren AO; Department of Pediatrics, Obstetrics and Gynecology, Division of Pediatric Hematology and Oncology, University Hospital of Geneva, Geneva, Switzerland., Friedrich C; Department of General Pediatrics and Pediatric Hematology/Oncology, University Children's Hospital, Klinikum Oldenburg AöR, Oldenburg, Germany., Juhnke BO; Department of Pediatric Hematology and Oncology, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany., Gerber NU; Department of Oncology, University Children's Hospital Zurich, Zurich, Switzerland., Kwiecien R; Institut für Biometrie und Klinische Forschung, Universitätsklinikum Münster, Münster, Germany., Girschick H; Kinder- und Jugendmedizin, Vivantes-Klinikum, Berlin Friedrichshain, Berlin, Germany., Höller A; Institute of Medical Biometry and Epidemiology, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany., Zapf A; Institute of Medical Biometry and Epidemiology, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany., von Hoff K; Department of Pediatric Hematology and Oncology, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany; Department of Pediatric Oncology/Hematology, Charité-University Medicine Berlin, Germany., Rutkowski S; Department of Pediatric Hematology and Oncology, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany.

Publikováno v: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2022 Mar; Vol. 164, pp. 30-38. Date of Electronic Publication: 2022 Feb 09.

Treatment of embryonal tumors with multilayered rosettes with carboplatin/etoposide induction and high-dose chemotherapy within the prospective P-HIT trial.

Autor: Juhnke BO; HIT-MED Study Centre, Clinic for Paediatric Haematology and Oncology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Gessi M; Neuropathology Unit, Division of Pathology, Fondazione Policlinico Universitario 'A Gemelli' IRCCS, Catholic University Rome, Rome, Italy., Gerber NU; Department of Oncology, University Children's Hospital Zürich, Zürich, Switzerland., Friedrich C; Department of Paediatrics and Paediatric Haematology/Oncology, University Children's Hospital, Klinikum Oldenburg AöR, Oldenburg, Germany., Mynarek M; HIT-MED Study Centre, Clinic for Paediatric Haematology and Oncology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., von Bueren AO; Department of Paediatrics, Obstetrics and Gynaecology, Division of Paediatric Haematology and Oncology, University Hospital of Geneva, Geneva, Switzerland., Haberler C; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, Vienna, Austria., Schüller U; Institute of Neuropathology, University Medical Centre Hamburg-Eppendorf and Research Institute Children's Cancer Center Hamburg, Hamburg, Germany., Kortmann RD; HIT Radiotherapy Reference Centre, Clinic for Radiotherapy, Leipzig University Medicine, Leipzig, Germany., Timmermann B; Department of Particle Therapy, University Hospital Essen, West German Proton Therapy Centre Essen (WPE), West German Cancer Centre (WTZ) and German Cancer Consortium (DKTK), Essen, Germany., Bison B; Institute for Diagnostic and Interventional Neuroradiology, University Hospital Augsburg, Augsburg, Germany.; HIT Neuroradiology Reference Centre, Institute for Diagnostic and Interventional Neuroradiology, University Hospital Würzburg, Würzburg, Germany., Warmuth-Metz M; HIT Neuroradiology Reference Centre, Institute for Diagnostic and Interventional Neuroradiology, University Hospital Würzburg, Würzburg, Germany., Kwiecien R; Institute of Biostatistics and Clinical Research, Faculty of Medicine, University of Münster, Münster, Germany., Pfister SM; Hopp Children's Cancer Center (KITZ), Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany., Spix C; Division of Childhood Cancer Epidemiology, Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany., Pietsch T; DGNN Brain Tumour Reference Centre, Institute of Neuropathology, University Hospital Bonn, Bonn, Germany., Kool M; Hopp Children's Cancer Center (KITZ), Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands., Rutkowski S; HIT-MED Study Centre, Clinic for Paediatric Haematology and Oncology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., von Hoff K; Department of Paediatric Oncology and Haematology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Publikováno v: Neuro-oncology [Neuro Oncol] 2022 Jan 05; Vol. 24 (1), pp. 127-137.