Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Kwee Poo, Yeo"'
Autor:
Shuen Yee Lee, Stephen F. Burns, Kenneth K.C. Ng, David J. Stensel, Liang Zhong, Frankie H.Y. Tan, Kar Ling Chia, Kai Deng Fam, Margaret M.C. Yap, Kwee Poo Yeo, Eric P.H. Yap, Chin Leong Lim
Publikováno v:
Antioxidants, Vol 9, Iss 3, p 221 (2020)
Fibroblast growth factor 21 (FGF21) and adiponectin increase the expression of genes involved in antioxidant pathways, but their roles in mediating oxidative stress and arterial stiffness with ageing and habitual exercise remain unknown. We explored
Externí odkaz:
https://doaj.org/article/327990e473124637ac9cd9d3a46b2943
Autor:
Chin Leong Lim, Margaret M. C. Yap, Frankie Tan, Stephen F. Burns, Kar Ling Chia, Kwee Poo Yeo, Eric P.H. Yap, Kenneth Ng, David J. Stensel, Shuen Yee Lee, Kai Deng Fam, Liang Zhong
Publikováno v:
Medicine & Science in Sports & Exercise. 52:370-380
Introduction: Ageing increases the prevalence of glucose intolerance, but exercise improves glucose homeostasis. The fibroblast growth factor 21 (FGF21)-adiponectin axis helps regulate glucose metabolism. However, the role of FGF21 in mediating gluco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214fab0fda5b3df57b6589463289e816
https://doi.org/10.1249/mss.0000000000002150
https://doi.org/10.1249/mss.0000000000002150
Autor:
Kai Deng Fam, Margaret M. C. Yap, Kwee Poo Yeo, Kenneth Ng, David J. Stensel, Liang Zhong, Kar Ling Chia, Frankie Tan, Eric P.H. Yap, Stephen F. Burns, Shuen Yee Lee, Chin Leong Lim
Publikováno v:
Antioxidants
Volume 9
Issue 3
Antioxidants, Vol 9, Iss 3, p 221 (2020)
Volume 9
Issue 3
Antioxidants, Vol 9, Iss 3, p 221 (2020)
Fibroblast growth factor 21 (FGF21) and adiponectin increase the expression of genes involved in antioxidant pathways, but their roles in mediating oxidative stress and arterial stiffness with ageing and habitual exercise remain unknown. We explored
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8356095e73c6162fd6025cacbe985b34
https://hdl.handle.net/10356/146268
https://hdl.handle.net/10356/146268
Autor:
Sanjay H. Chotirmall, Shuen Yee Lee, Margaret M. C. Yap, Kwee Poo Yeo, Kar Ling Chia, Eric P.H. Yap, Kai Deng Fam, Jorming Goh, Chin Leong Lim
Publikováno v:
Experimental physiologyREFERENCES. 105(4)
What is the central question of this study? Fibroblast growth factor 21 (FGF21) plays important therapeutic roles in metabolic diseases but is associated with bone loss, through insulin-like growth factor binding protein 1 (IGFBP1), in animals. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ecbd73290d294b6a07b12cadae4a35
https://pubmed.ncbi.nlm.nih.gov/31977105
https://pubmed.ncbi.nlm.nih.gov/31977105
Autor:
Danny Soon, Shufen T. H. Lim, Vikram Sinha, Kenneth F. Mace, S. L. Choi, Kwee Poo Yeo, Daniel C. Howey
Publikováno v:
The Journal of Clinical Pharmacology. 54:792-799
LY2605541 is a novel basal insulin analog with a prolonged duration of action. Two Phase I studies assessed LY2605541 pharmacokinetics (PK), glucodynamics (GD), and tolerability in healthy subjects. In Study 1, 33 subjects received single subcutaneou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75e4c0639375f756cee4d31752fe77a4
https://doi.org/10.1002/jcph.276
https://doi.org/10.1002/jcph.276
Publikováno v:
Journal of Diabetes Investigation
Introduction This phase 3, randomized, open-label study compared efficacy and safety of basal insulin peglispro with insulin glargine after 26 weeks of treatment when added to oral antihyperglycemic medications in insulin-naive Asian patients with ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d239bbb61d7958cfd42c195186a571e
https://pubmed.ncbi.nlm.nih.gov/28371567
https://pubmed.ncbi.nlm.nih.gov/28371567
Autor:
Mark Fineman, Prajakti A. Kothare, Yoshitaka Isaka, Ayuko Yamamura, Helle Linnebjerg, Kwee Poo Yeo, Kazunori Uenaka, Hirofumi Shigeta, Choo Hua Teng, Kenneth F. Mace, Shin Irie, Amparo de la Peña, Yukikuni Sakata
Publikováno v:
The Journal of Clinical Pharmacology. 48:1389-1399
In this single-blind, parallel, placebo-controlled study, the pharmacokinetics, pharmacodynamics, tolerability, and safety of subcutaneous exenatide were evaluated in 40 Japanese patients with type 2 diabetes. Patients were allocated to 4 groups and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81ade19a595626afc3882fa3126a67f
https://doi.org/10.1177/0091270008323750
https://doi.org/10.1177/0091270008323750
Autor:
Stephen D. Wise, Helen B. Isaac, Shan Hong Huang, Ronan P. Kelly, Chung-Yung J. Lee, Barry Halliwell, Kwee Poo Yeo, Lorraine Teng
Publikováno v:
Free Radical Research. 42:514-522
Vitamin C is a potent antioxidant in vitro and has been reported to act as a vasodilator, possibly by increasing nitric oxide bioavailability. This study examined the antioxidant and vascular effects of a single large oral dose of vitamin C in 26 hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab890368a29b6dd849dcd4e3a43ffa3e
https://doi.org/10.1080/10715760802087431
https://doi.org/10.1080/10715760802087431
Autor:
Richard W. Peck, Alan Pan, Leyan Teng, Danny Soon, Kwee Poo Yeo, Stephen D. Wise, Stephen L. Lowe
Publikováno v:
Psychoneuroendocrinology. 31:473-484
The objective of the study was to assess l-5-hydroxytryptophan's (l-5HTP) augmentation effect on the neuroendocrine response to a SSRI (citalopram). A neuroendocrine challenge study was conducted in healthy Asian male subjects. The neuroendocrine res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::950129562f42686b07483456f4d45625
https://doi.org/10.1016/j.psyneuen.2005.11.005
https://doi.org/10.1016/j.psyneuen.2005.11.005
Autor:
James Voelker, Stephen L. Lowe, Jennifer L. Burkey, Ming Tung Lim, Stephen D. Wise, Kwee Poo Yeo
Publikováno v:
British Journal of Clinical Pharmacology. 61:200-210
Aims The aim of this study was to evaluate the effect of rifampicin co-administration on the pharmacokinetics of ruboxistaurin and its active metabolite, N-desmethyl ruboxistaurin and, in addition, to compare the changes in pharmacokinetics of ruboxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b09a18e5374613c046f602f0b1e2a3
https://doi.org/10.1111/j.1365-2125.2005.02540.x
https://doi.org/10.1111/j.1365-2125.2005.02540.x