Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kwee L Yong"'
Autor:
Kwee L. Yong, Samantha Hinsley, Holger W. Auner, Ceri Bygrave, Martin F. Kaiser, Karthik Ramasamy, Ruth M. de Tute, Debbie Sherratt, Louise Flanagan, Mamta Garg, Stephen Hawkins, Catherine Williams, Jamie Cavenagh, Neil K. Rabin, James Croft, Gareth Morgan, Faith Davies, Roger G. Owen, Sarah R. Brown
Publikováno v:
Haematologica, Vol 106, Iss 10 (2021)
The proteasome inhibitors, carfilzomib and bortezomib, are widely used to treat myeloma but head-to-head comparisons have produced conflicting results. We compared the activity of these proteasome inhibitors in combination with cyclophosphamide and d
Externí odkaz:
https://doaj.org/article/ba5b64df09aa40b1b00ecd0bd0337518
Autor:
Joanne Land, Julia Hackett, Govundeep Sidhu, Malgorzata Heinrich, Orla McCourt, Kwee L. Yong, Abi Fisher, Rebecca J. Beeken
Publikováno v:
Supportive Care in Cancer. 30:6273-6286
Purpose The Myeloma: Advancing Survival Cancer Outcomes Trial (MASCOT) tested the impact of a supervised exercise programme on fatigue, clinical, and patient-reported outcomes in multiple myeloma [MM] patients. The current study explored MM patients
Autor:
Brian A. Walker, Anjan Thakurta, Karthik Ramasamy, Rafat Abonour, Sarah Gooding, Erin Flynt, Gareth J. Morgan, William E. Pierceall, Frits van Rhee, Kwee L. Yong, Naser Ansari-Pour, Mohammad I. Abu Zaid, Jonathan Williams, Magdalena Czader, Patrick Blaney, Outi Salminen, Evelyn Fitzsimons, Lin Wang, Chih-Chao Hsu, Mohammad H. Kazeroun, Akhil Khera, Tasneem Kausar, Cody Ashby, Aarif Ahsan, Parvathi Sudha
Supplementary Data from Myeloma Genome Project Panel is a Comprehensive Targeted Genomics Panel for Molecular Profiling of Patients with Multiple Myeloma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03647cf73b69e26d86d7eecfe585586e
https://doi.org/10.1158/1078-0432.22488255.v1
https://doi.org/10.1158/1078-0432.22488255.v1
Autor:
Brian A. Walker, Anjan Thakurta, Karthik Ramasamy, Rafat Abonour, Sarah Gooding, Erin Flynt, Gareth J. Morgan, William E. Pierceall, Frits van Rhee, Kwee L. Yong, Naser Ansari-Pour, Mohammad I. Abu Zaid, Jonathan Williams, Magdalena Czader, Patrick Blaney, Outi Salminen, Evelyn Fitzsimons, Lin Wang, Chih-Chao Hsu, Mohammad H. Kazeroun, Akhil Khera, Tasneem Kausar, Cody Ashby, Aarif Ahsan, Parvathi Sudha
Purpose:We designed a comprehensive multiple myeloma targeted sequencing panel to identify common genomic abnormalities in a single assay and validated it against known standards.Experimental Design:The panel comprised 228 genes/exons for mutations,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7572ae612990c4d5220e4e2f0633a9
https://doi.org/10.1158/1078-0432.c.6532674
https://doi.org/10.1158/1078-0432.c.6532674
Autor:
Kwee L. Yong, Sergio A. Quezada, Javier Herrero, Martin Pule, Manuel Rodriguez-Justo, Anthony Brooks, Dominic Patel, Oliver C. Cohen, Dunnya De-Silva, Huw Richards, Selina J. Chavda, Andrew J.S. Furness, Daria Galas-Filipowicz, Melody Chin, Lucia Conde, Jake Y. Henry, Ehsan Ghorani, Lydia Lee, Nouf Alrasheed
Purpose:Immune dysregulation is described in multiple myeloma. While preclinical models suggest a role for altered T-cell immunity in disease progression, the contribution of immune dysfunction to clinical outcomes remains unclear. We aimed to charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ae590a362cc2c1903d91f6a3589fbc
https://doi.org/10.1158/1078-0432.c.6528762.v1
https://doi.org/10.1158/1078-0432.c.6528762.v1
Autor:
Brian A. Walker, Anjan Thakurta, Karthik Ramasamy, Rafat Abonour, Sarah Gooding, Erin Flynt, Gareth J. Morgan, William E. Pierceall, Frits van Rhee, Kwee L. Yong, Naser Ansari-Pour, Mohammad I. Abu Zaid, Jonathan Williams, Magdalena Czader, Patrick Blaney, Outi Salminen, Evelyn Fitzsimons, Lin Wang, Chih-Chao Hsu, Mohammad H. Kazeroun, Akhil Khera, Tasneem Kausar, Cody Ashby, Aarif Ahsan, Parvathi Sudha
Supplementary Table from Myeloma Genome Project Panel is a Comprehensive Targeted Genomics Panel for Molecular Profiling of Patients with Multiple Myeloma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::009c17854dd0e78ee8d055cdc7ac5c73
https://doi.org/10.1158/1078-0432.22488219.v1
https://doi.org/10.1158/1078-0432.22488219.v1
Autor:
Kwee L. Yong, Sergio A. Quezada, Javier Herrero, Martin Pule, Manuel Rodriguez-Justo, Anthony Brooks, Dominic Patel, Oliver C. Cohen, Dunnya De-Silva, Huw Richards, Selina J. Chavda, Andrew J.S. Furness, Daria Galas-Filipowicz, Melody Chin, Lucia Conde, Jake Y. Henry, Ehsan Ghorani, Lydia Lee, Nouf Alrasheed
Supplementary tables and figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2847b1021ef16d14d91d85918f959571
https://doi.org/10.1158/1078-0432.22474356.v1
https://doi.org/10.1158/1078-0432.22474356.v1
Autor:
Brian A. Walker, Anjan Thakurta, Karthik Ramasamy, Rafat Abonour, Sarah Gooding, Erin Flynt, Gareth J. Morgan, William E. Pierceall, Frits van Rhee, Kwee L. Yong, Naser Ansari-Pour, Mohammad I. Abu Zaid, Jonathan Williams, Magdalena Czader, Patrick Blaney, Outi Salminen, Evelyn Fitzsimons, Lin Wang, Chih-Chao Hsu, Mohammad H. Kazeroun, Akhil Khera, Tasneem Kausar, Cody Ashby, Aarif Ahsan, Parvathi Sudha
Supplementary Figure from Myeloma Genome Project Panel is a Comprehensive Targeted Genomics Panel for Molecular Profiling of Patients with Multiple Myeloma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0634ab44b6f8d774d07e3778e893306c
https://doi.org/10.1158/1078-0432.22488240
https://doi.org/10.1158/1078-0432.22488240
Publikováno v:
The Lancet. 397:410-427
Multiple myeloma is the second most common haematological malignancy in high-income countries, and typically starts as asymptomatic precursor conditions-either monoclonal gammopathy of undetermined significance or smouldering multiple myeloma-in whic
Autor:
Parvathi Sudha, Aarif Ahsan, Cody Ashby, Tasneem Kausar, Akhil Khera, Mohammad H. Kazeroun, Chih-Chao Hsu, Lin Wang, Evelyn Fitzsimons, Outi Salminen, Patrick Blaney, Magdalena Czader, Jonathan Williams, Mohammad I. Abu Zaid, Naser Ansari-Pour, Kwee L. Yong, Frits van Rhee, William E. Pierceall, Gareth J. Morgan, Erin Flynt, Sarah Gooding, Rafat Abonour, Karthik Ramasamy, Anjan Thakurta, Brian A. Walker
Publikováno v:
Clin Cancer Res
Purpose: We designed a comprehensive multiple myeloma targeted sequencing panel to identify common genomic abnormalities in a single assay and validated it against known standards. Experimental Design: The panel comprised 228 genes/exons for mutation