Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Kwasigroch, Thomas E."'
Autor:
Millar, William A, Armstrong, Landon R, Becker, Robert M, Musick, Adam N, Ryan, David B, Kwasigroch, Thomas E
Publikováno v:
Advances in Medical Education & Practice; Nov2023, Vol. 14, p1279-1284, 6p
Publikováno v:
ETSU Faculty Works.
Forelimbs of Day 11 and Day 12 embryonic mice were excised and cultured for 3 d in the presence of either 0.25 μg (8×10-7 M), 0.5 μg(1.7×10-6 M), or 1.0 μg (3.3×10-6 M) of all-rans retinoic acid (RA) per milliliter of culture medium. Cultured l
Externí odkaz:
https://dc.etsu.edu/etsu-works/13411
Autor:
Kwasigroch, Thomas E., Skalko, R. G.
Publikováno v:
ETSU Faculty Works.
Caffeine and retinoic acid were examined for effects upon limb morphogenesis and upon creatine kinase (CK) as a measure of limb myogenesis. Caffeine at 200 mg/kg, i.p., on E11 produced a low level of forelimb (1.2%) and hindlimb (2.0%) defects. Retin
Externí odkaz:
https://dc.etsu.edu/etsu-works/13262
Publikováno v:
ETSU Faculty Works.
Brachypod (bpH/bpH), an autosomal mutation in mice, is characterized by a shortening of the long bones and paws, and a delay or absence of ossification in some of the distal limb elements. The present study represents a detailed description of the br
Externí odkaz:
https://dc.etsu.edu/etsu-works/13147
Autor:
Kwasigroch, Thomas E., Kochhar, D. M.
Publikováno v:
ETSU Faculty Works.
Maternal administration of a single dose of retinoic acid (vitamin A acid, 100 mg/kg) on either the 11 th, 11 1/2, 12th, 12 1/2, 13th or 13 1/2 day of gestation produced phocomelia or partial phocomelia in ICR/DUB fetuses. The results depended upon t
Externí odkaz:
https://dc.etsu.edu/etsu-works/13148
Publikováno v:
ETSU Faculty Works.
The toxic interaction of caffeine and phenytoin during pregnancy was investigated in mice of the ICR strain on E10 of gestation. Caffeine, over a range of dosages, showed limited embryotoxic activity. Phenytoin was also weakly teratogenic and dosages
Externí odkaz:
https://dc.etsu.edu/etsu-works/13036
Autor:
Kwasigroch, Thomas E., Skalko, R. G.
Publikováno v:
ETSU Faculty Works.
Pregnant mice were treated on gestation Day 11 (E11) with a single dose of either hydroxyurea (HU, 250 mg/kg) or 5-bromo-2′deoxyuridine (BrdU, 500 mg/kg), or with a combination of the two agents. The dams were either allowed to go to term, when the
Externí odkaz:
https://dc.etsu.edu/etsu-works/13012
Publikováno v:
ETSU Faculty Works.
Retinoic acid, suspended in cottonseed oil, was administered via gavage to pregnant mice (ICR strain) on day 11 (E 11) of gestation at doses of either 20, 40, or 80 mg/kg. Fetuses were examined for external malformations on day 17 (E 17). Retinoic ac
Externí odkaz:
https://dc.etsu.edu/etsu-works/12997
Autor:
Olive, Kenneth E., Kwasigroch, Thomas E., Wooten, Daniel J., Lybrand, Cynthia, Peeples, Catherine R.
Publikováno v:
ETSU Faculty Works.
Problem Providing medical students with resources to make effective career choices is challenging for medical schools as career options outnumber the formal clinical rotations students can experience during their undergraduate education. Approach In
Externí odkaz:
https://dc.etsu.edu/etsu-works/15285
Autor:
Kwasigroch, Thomas E., Bullen, Michael
Publikováno v:
ETSU Faculty Works.
Isotretinoin (13‐cis‐RA) is known to be teratogenic in humans and laboratory animals. The relatively low potency of 13‐cis‐RA in NRMI mice in comparison to the all‐trans isomer has been proposed to be due to minimal transfer across the plac
Externí odkaz:
https://dc.etsu.edu/etsu-works/12465