Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Kwangwoon Lee"'
Autor:
Zhipeng A Wang, Christopher J Millard, Chia-Liang Lin, Jennifer E Gurnett, Mingxuan Wu, Kwangwoon Lee, Louise Fairall, John WR Schwabe, Philip A Cole
Publikováno v:
eLife, Vol 9 (2020)
Histone acetylation regulates chromatin structure and gene expression and is removed by histone deacetylases (HDACs). HDACs are commonly found in various protein complexes to confer distinct cellular functions, but how the multi-subunit complexes inf
Externí odkaz:
https://doaj.org/article/1b9752d5c4ac41d38b02862542d44d42
Autor:
Davi R Ortega, Guoya Mo, Kwangwoon Lee, Hongjun Zhou, Jerome Baudry, Frederick W Dahlquist, Igor B Zhulin
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 11, p e1003337 (2013)
Bacterial chemotaxis is one of the best studied signal transduction pathways. CheW is a scaffold protein that mediates the association of the chemoreceptors and the CheA kinase in a ternary signaling complex. The effects of replacing conserved Arg62
Externí odkaz:
https://doaj.org/article/2b9368f8d60644a2bce96db8a77ed23d
Autor:
Zhipeng A. Wang, Jonathan W. Markert, Samuel D. Whedon, Maheeshi Yapa Abeywardana, Kwangwoon Lee, Hanjie Jiang, Carolay Suarez, Hening Lin, Lucas Farnung, Philip A. Cole
Publikováno v:
Journal of the American Chemical Society. 145:6811-6822
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9afb76a5dbbe5afefc9f402a45c111c0
https://doi.org/10.1021/jacs.2c13512
https://doi.org/10.1021/jacs.2c13512
Autor:
Zhipeng A. Wang, Samuel D. Whedon, Mingxuan Wu, Siyu Wang, Edward A. Brown, Ananya Anmangandla, Liam Regan, Kwangwoon Lee, Jianfeng Du, Jun Young Hong, Louise Fairall, Taylor Kay, Hening Lin, Yingming Zhao, John W. R. Schwabe, Philip A. Cole
Publikováno v:
Journal of the American Chemical Society. 144:3360-3364
We describe a new method to produce histone H2B by semisynthesis with an engineered sortase transpeptidase. N-Terminal tail site-specifically modified acetylated, lactylated, and β-hydroxybutyrylated histone H2Bs were incorporated into nucleosomes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b42f643da4cea27457c1d37bbc02ee
https://doi.org/10.1021/jacs.1c13555
https://doi.org/10.1021/jacs.1c13555
Autor:
Ranajeet Ghose, Kwangwoon Lee, Andrea Piserchio, Eric A. Kumar, Rinat R. Abzalimov, Kevin N. Dalby, Kimberly Long
Publikováno v:
Protein Sci
The calmodulin (CaM) activated α-kinase, eukaryotic elongation factor 2 kinase (eEF-2 K), plays a central role in regulating translational elongation by phosphorylating eukaryotic elongation factor 2 (eEF-2), thereby reducing its ability to associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352b6e8b070cf7720d8c691ec4e9a7c5
https://doi.org/10.1002/pro.4087
https://doi.org/10.1002/pro.4087
Publikováno v:
Current opinion in chemical biology. 70
Classical histone deacetylases (HDACs) are enzymes that can hydrolytically cleave acetyl-Lys in histones and other proteins and serve as established drug targets in some forms of cancer. Class I HDACs 1-3 typically exist in a range of multiprotein co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::735f3bb9456b01f2550da4613c1971d2
https://pubmed.ncbi.nlm.nih.gov/35803024
https://pubmed.ncbi.nlm.nih.gov/35803024
Publikováno v:
Biophysical Journal. 122:482a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edd56d34cb47ee351eb44a32b3508afc
https://doi.org/10.1016/j.bpj.2022.11.2579
https://doi.org/10.1016/j.bpj.2022.11.2579
Publikováno v:
Protein Sci
Eukaryotic elongation factor 2 kinase (eEF‐2K) regulates protein synthesis by phosphorylating eukaryotic elongation factor 2 (eEF‐2), thereby reducing its affinity for the ribosome and suppressing global translational elongation rates. eEF‐2K i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8aee75ced0e05eecac1864ac699aa91
https://doi.org/10.1002/pro.3753
https://doi.org/10.1002/pro.3753
Autor:
John W.R. Schwabe, Philip A. Cole, Zhipeng A. Wang, Louise Fairall, Kwangwoon Lee, Chia-Liang Lin, Jennifer E Gurnett, Mingxuan Wu, Christopher J. Millard
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Histone acetylation regulates chromatin structure and gene expression and is removed by histone deacetylases (HDACs). HDACs are commonly found in various protein complexes to confer distinct cellular functions, but how the multi-subunit complexes inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f371d32e4ea9d2cb683c47207c5131c8
https://elifesciences.org/articles/57663
https://elifesciences.org/articles/57663