Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Kwangok P. Nickel"'
Autor:
Aakarsha Rao, Milan S. Stosic, Chitrasen Mohanty, Dhruthi Suresh, Albert R. Wang, Denis L. Lee, Kwangok P. Nickel, Darshan S. Chandrashekar, Randall J. Kimple, Paul F. Lambert, Christina Kendziorski, Trine B. Rounge, Gopal Iyer
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Human papillomaviruses (HPV), most commonly HPV16, are associated with a subset of head and neck squamous cell carcinoma (HNSCC) tumors, primarily oropharyngeal carcinomas, with integration of viral genomes into host chromosomes associated with worse
Externí odkaz:
https://doaj.org/article/29af87b7f5044f5da49d0afc0c1ed131
Autor:
Grace C. Blitzer, Nicole M. Rogus‐Pulia, Cristina Paz, Kwangok P. Nickel, Vanessa L. Cannaday, Cynthia A. Kelm‐Nelson, Sailendharan Sudakaran, Richard J. Chappell, Tiffany Glazer, Randall J. Kimple
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 7, Iss 4, Pp 1018-1024 (2022)
Abstract Objective Radiation therapy (RT) for head and neck cancer (HNC) can result in severe xerostomia, or the subjective feeling of dry mouth. Characterizing xerostomia is critical to designing future clinical trials investigating how to improve H
Externí odkaz:
https://doaj.org/article/73206a9a0e8142a8901e7d44f33b9109
Autor:
Miranda B. Carper, Saumya Goel, Anna M. Zhang, Jeffrey S. Damrauer, Stephanie Cohen, Matthew P. Zimmerman, Gabrielle M. Gentile, Kshitij Parag-Sharma, Ryan M. Murphy, Kotaro Sato, Kwangok P. Nickel, Randall J. Kimple, Wendell G. Yarbrough, Antonio L. Amelio
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 29, Iss , Pp 100799- (2022)
Head and neck squamous cell carcinoma (HNSCC) is the 6th most common cancer worldwide and incidence rates are continuing to rise globally. Patients often present with locally advanced disease and a staggering 50% chance of relapse following treatment
Externí odkaz:
https://doaj.org/article/1f8dd06da4b643fbba1a9c0c8dad07c8
Autor:
Raghavan Chinnadurai, Paul D. Bates, Keith A. Kunugi, Kwangok P. Nickel, Larry A. DeWerd, Christian M. Capitini, Jacques Galipeau, Randall J. Kimple
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Mesenchymal stromal cells (MSCs) are being tested as a cell therapy in clinical trials for dozens of inflammatory disorders, with varying levels of efficacy reported. Suitable and robust preclinical animal models for testing the safety and efficacy o
Externí odkaz:
https://doaj.org/article/9f6a95f5cd4c45778cceb90c01c5c952
Autor:
Pippa F. Cosper, Lindsey Abel, Yong-Syu Lee, Cristina Paz, Saakshi Kaushik, Kwangok P. Nickel, Roxana Alexandridis, Jacob G. Scott, Justine Y. Bruce, Randall J. Kimple
Publikováno v:
Cancers, Vol 12, Iss 2, p 419 (2020)
Patient-derived model systems are important tools for studying novel anti-cancer therapies. Patient-derived xenografts (PDXs) have gained favor over the last 10 years as newer mouse strains have improved the success rate of establishing PDXs from pat
Externí odkaz:
https://doaj.org/article/dfb780cb1ba44743b15c32cddcb95c26
Autor:
Randall J. Kimple, Deric L. Wheeler, Justine Y. Bruce, Kwangok P. Nickel, Mari Iida, Rong Hu, Irene M. Ong, Emmanuel Sampene, Michael M. Fisher, Amal M. Javaid, Margot C. Miller, Prashanth J. Prabakaran, Adam D. Swick
Supplemental Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84fa67167bf6f1c3a46eb82f215b0f2c
https://doi.org/10.1158/1535-7163.22503076
https://doi.org/10.1158/1535-7163.22503076
Autor:
Randall J. Kimple, Shuang G. Zhao, Ticiana A. Leal, Kwangok P. Nickel, Colin A. Longhurst, Paul A. Clark, Lindsey Abel, Saakshi Kaushik, Justin H. Skiba, Ashley C. Kromke, Haley J. VanBeek, Jacob H. Elnaggar, Andrew M. Baschnagel
M6620, a selective ATP-competitive inhibitor of the ATM and RAD3-related (ATR) kinase, is currently under investigation with radiation in patients with non–small cell lung cancer (NSCLC) brain metastases. We evaluated the DNA damage response (DDR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1022828dcc5353716a90d96a2e4e7f69
https://doi.org/10.1158/1535-7163.c.6543216
https://doi.org/10.1158/1535-7163.c.6543216
Autor:
Randall J. Kimple, Shuang G. Zhao, Ticiana A. Leal, Kwangok P. Nickel, Colin A. Longhurst, Paul A. Clark, Lindsey Abel, Saakshi Kaushik, Justin H. Skiba, Ashley C. Kromke, Haley J. VanBeek, Jacob H. Elnaggar, Andrew M. Baschnagel
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef8d8e3df2d81fc342a831aff1366d3
https://doi.org/10.1158/1535-7163.22521897
https://doi.org/10.1158/1535-7163.22521897
Autor:
Andrew M. Baschnagel, Randall J. Kimple, Gopal Iyer, Kwangok P. Nickel, Darya Buehler, Colin A. Longhurst, Samantha T. Bradley, Saakshi Kaushik, Sean R. Brennan, Margot C. Miller, Justin H. Skiba, Michael M. Fisher, Gopika SenthilKumar
Supplementary Table 1. Short Tandem Repeat analysis of cell lines used in this study. Supplementary Table 2. Antibodies used in this study. Supplemental Table 3: Dose Enhancement factors at survival fraction of 0.1 (DEF0.1) and Pvalues for radiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68084ff4a9f045bf6ebd12aaefde4f47
https://doi.org/10.1158/1535-7163.22521793.v1
https://doi.org/10.1158/1535-7163.22521793.v1
Autor:
Dustin A. Deming, Melissa C. Skala, Randall J. Kimple, Michael F. Bassetti, Irene M. Ong, Michael A. Newton, Kristina A. Matkowskyj, Kayla K. Lemmon, Mark E. Burkard, Evie H. Carchman, Devon Miller, Christine M. Walsh, Linda Clipson, Demetra P. Korkos, Susan N. Payne, Rosabella T. Pitera, Rebecca A. DeStefanis, Philip B. Emmerich, Carley M. Sprackling, Alyssa K. DeZeeuw, Kwangok P. Nickel, Mohammad Rezaul Karim, Joe T. Sharick, Amani A. Gillette, Christopher P. Babiarz, Alexander E. Yueh, Peter F. Favreau, Cheri A. Pasch
Dot plots corresponding to population distribution curves and graphs of individual replicates for bar graphs in Figure 4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7330c7bce5376c4f183eb6067b2815ec
https://doi.org/10.1158/1078-0432.22469583
https://doi.org/10.1158/1078-0432.22469583