Zobrazeno 1 - 10
of 486
pro vyhledávání: '"Kwang-Seok Ahn"'
Autor:
Suneel Kumar, Stephen O. Mathew, Ravindra Prasad Aharwal, Hardeep Singh Tulli, Chakrabhavi Dhananjaya Mohan, Gautam Sethi, Kwang-Seok Ahn, Kassidy Webber, Sardul Singh Sandhu, Anupam Bishayee
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 160 (2023)
Cancer represents the second most deadly disease and one of the most important public health concerns worldwide. Surgery, chemotherapy, radiation therapy, and immune therapy are the major types of treatment strategies that have been implemented in ca
Externí odkaz:
https://doaj.org/article/9a36679832be4735aff744f0e9f34c6a
Autor:
Sepideh Mirzaei, Kiavash Hushmandi, Amirhossein Zabolian, Hossein Saleki, Seyed Mohammad Reza Torabi, Adnan Ranjbar, SeyedHesam SeyedSaleh, Seyed Omid Sharifzadeh, Haroon Khan, Milad Ashrafizadeh, Ali Zarrabi, Kwang-seok Ahn
Publikováno v:
Molecules, Vol 26, Iss 8, p 2382 (2021)
The failure of chemotherapy is a major challenge nowadays, and in order to ensure effective treatment of cancer patients, it is of great importance to reveal the molecular pathways and mechanisms involved in chemoresistance. Cisplatin (CP) is a plati
Externí odkaz:
https://doaj.org/article/803f7e80382f440c9a724b42d4c24021
Autor:
Hara Lim, Jinbong Park, Hye-Lin Kim, JongWook Kang, Mi-Young Jeong, Dong-Hyun Youn, Yunu Jung, Yong-Il Kim, Hyun-Ju Kim, Kwang-Seok Ahn, Su-Jin Kim, Seong-Kyu Choe, Seung-Heon Hong, Jae-Young Um
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Chrysophanic acid (CA) is a member of the anthraquinone family abundant in rhubarb, a widely used herb for obesity treatment in Traditional Korean Medicine. Though several studies have indicated numerous features of CA, no study has yet reported the
Externí odkaz:
https://doaj.org/article/14dc38aeec644bcba697aab9e17bbce0
Autor:
Na Young Kim, Dukanya Dukanya, Gautam Sethi, Swamy S Girimanchanaika, Jirui Yang, Omantheswara Nagaraja, Ananda Swamynayaka, Divakar Vishwanath, Keerthikumara Venkantesha, Shreeja Basappa, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Mahendra Madegowda, Alexey Sukhorukov, Vijay Pandey, Peter E. Lobie, Basappa Basappa, Kwang Seok Ahn
Publikováno v:
Translational Oncology, Vol 49, Iss , Pp 102101- (2024)
Small molecule-driven JNK activation has been found to induce apoptosis and paraptosis in cancer cells. Herein pharmacological effects of synthetic oxazine (4aS, 7aS)-3-((4-(4‑chloro-2-fluorophenyl)piperazin-1-yl)methyl)-4-phenyl-4, 4a, 5, 6, 7, 7a
Externí odkaz:
https://doaj.org/article/6719bc3a38394d8688d5d7884b2aea4a
Autor:
Woo Yong Park, Gahee Song, Ja Yeon Park, Kwang Seok Ahn, Hyun Jeong Kwak, Jinbong Park, Jun Hee Lee, Jae-Young Um
Publikováno v:
Cell Death and Disease, Vol 13, Iss 6, Pp 1-11 (2022)
Abstracts Benign prostate hyperplasia (BPH) is an age-related disease in men characterized by the growth of prostate cells and hyperproliferation of prostate tissue. This condition is closely related to chronic inflammation. In this study, we highlig
Externí odkaz:
https://doaj.org/article/d5ebaa6d72da4935bccc2d724578829f
Autor:
Jong Hyun Lee, Chakrabhavi Dhananjaya Mohan, Amudha Deivasigamani, Young Yun Jung, Shobith Rangappa, Salundi Basappa, Arunachalam Chinnathambi, Tahani Awad Alahmadi, Sulaiman Ali Alharbi, Manoj Garg, Zhi-Xiu Lin, Kanchugarakoppal S. Rangappa, Gautam Sethi, Kam Man Hui, Kwang Seok Ahn
Publikováno v:
Journal of Advanced Research, Vol 26, Iss , Pp 83-94 (2020)
Introduction: Epithelial-mesenchymal transition (EMT) is a process of transdifferentiation where epithelial cells attain mesenchymal phenotype to gain invasive properties and thus, can contribute to metastasis of tumor cells. Objectives: The antimeta
Externí odkaz:
https://doaj.org/article/b49452f32a3546068e13458d992b5aa4
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9848 (2022)
CXCR7 and CXCR4 are G protein-coupled receptors (GPCRs) that can be stimulated by CXCL12 in various human cancers. CXCR7/4–CXCL12 binding can initiate activation of multiple pathways including JAK/STAT and manganese superoxide dismutase (MnSOD) sig
Externí odkaz:
https://doaj.org/article/f053fed18faa4502ab64f314fd2388af
Autor:
Suresha N. Deveshegowda, Prashant K. Metri, Rashmi Shivakumar, Ji-Rui Yang, Shobith Rangappa, Ananda Swamynayaka, Muthu K. Shanmugam, Omantheswara Nagaraja, Mahendra Madegowda, Priya Babu Shubha, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Vijay Pandey, Kwang Seok Ahn, Peter E. Lobie, Basappa Basappa
Publikováno v:
Molecules, Vol 27, Iss 9, p 2848 (2022)
A number of uracil amides cleave poly (ADP-ribose) polymerase and therefore novel thiouracil amide compounds were synthesized and screened for the loss of cell viability in a human-estrogen-receptor-positive breast cancer cell line. The synthesized c
Externí odkaz:
https://doaj.org/article/835b5bddc7f74e5c85ff91e48605dc4b
Autor:
Young Yun Jung, Jae-Young Um, Arunachalam Chinnathambi, Chandramohan Govindasamy, Gautam Sethi, Kwang Seok Ahn
Publikováno v:
Biology, Vol 11, Iss 3, p 366 (2022)
Leelamine (LEE) has recently attracted significant attention for its growth inhibitory effects against melanoma, breast cancer, and prostate cancer cells; however, its impact on hematological malignancies remains unclear. Here, we first investigate t
Externí odkaz:
https://doaj.org/article/ca4e2233d43b41989b26938951302c3d
Publikováno v:
Phytochemistry Letters. 52:92-103